Results 1 to 10 of about 80,148 (202)
Lancet, The, 2015 The broad importance of dementia is undisputed, with Alzheimer's disease justifiably getting the most attention. However, dementia with Lewy bodies and Parkinson's disease dementia, now called Lewy body dementias, are the second most common type of degenerative dementia in patients older than 65 years.
Zuzana Walker +2 more
exaly +6 more sources
More than a rumor spreads in Parkinson’s disease. [PDF]
Frontiers in Human Neuroscience, 2016 As Parkinson's disease progresses, a massive loss of dopaminergic neurons is accompanied by accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies and Lewy neurites.
Natalia Cecilia Prymaczok +2 more
doaj +4 more sources
Clinics in Geriatric Medicine, 2018 While Alzheimer’s disease is the most common and widely known cause of dementia, it is not the only cause. Dementia with Lewy Bodies (DLB), in fact, may be the second most common cause of progressive dementia but it is certainly less well ...
Ansello, Edward F.
core +4 more sources
Journal of the Anus, Rectum and Colon, 2019 We systematically reviewed literature regarding "Lewy body constipation", i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms.
Ryuji Sakakibara +2 more
doaj +4 more sources
Proceedings of the National Academy of Sciences, 2006 Lewy bodies (LB) in the substantia nigra are a cardinal pathological feature of Parkinson's disease, but they occur in a number of neurodegenerative diseases and can be widespread in the nervous system. The characteristics, locations, and composition of LB are reviewed, with particular attention to α-synuclein (α-SYN), which appears to be the major ...
+5 more sources
Sex differences in clinical cognitive impairment with Lewy bodies: a Chinese multicenter study
Biology of Sex Differences, 2022 Highlights There are significant sex differences in Chinese population with cognitive impairment in Lewy body disease. Women were more common in dementia with Lewy bodies and mild cognitive impairment with Lewy bodies cases, had more frequent and severe ...
Jinghuan Gan +15 more
doaj +1 more source
I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review [PDF]
Journal of Movement Disorders, 2015 Lewy body-related disorders are characterized by the presence of Lewy bodies and Lewy neurites, which have abnormal aggregations of α-synuclein in the nigral and extranigral areas, including in the heart.
Eun Joo Chung, Sang Jin Kim
doaj +1 more source
Assessment of genetic risk for improved clinical-neuropathological correlations
Acta Neuropathologica Communications, 2020 In the clinical diagnosis of dementia with Lewy bodies, distinction from Alzheimer’s disease is suboptimal and complicated by shared genetic risk factors and frequent co-pathology.
Barbara E. Spencer +3 more
doaj +1 more source
Programme Grants for Applied Research, 2021 Background: Lewy body dementia, comprising both dementia with Lewy bodies and Parkinson’s disease dementia, is the second commonest cause of neurodegenerative dementia.
John T O’Brien +17 more
doaj +1 more source
Interaction between coxsackievirus B3 infection and α-synuclein in models of Parkinson's disease.
PLoS Pathogens, 2021 Parkinson's disease (PD) is one of the most common neurodegenerative diseases. PD is pathologically characterized by the death of midbrain dopaminergic neurons and the accumulation of intracellular protein inclusions called Lewy bodies or Lewy neurites ...
Soo Jin Park, Uram Jin, Sang Myun Park
doaj +2 more sources