Results 21 to 30 of about 796,122 (288)

The Alzheimer variant of Lewy body disease: A pathologically confirmed case-control study [PDF]

, 2005
The objective of the study was to identify clinical features that distinguish patients with dementia with Lewy bodies (DLB), who were classified as Alzheimer's disease ( AD) patients, from patients with AD.
Müller, U., Neumann, M., Kretzschmar, H., Perneczky, R., Kurz, A., Förstl, Hans, Mösch, D., Busch, R., Perneczky, R.;Mösch, D.;Neumann, M.;Kretzschmar, H.;Müller, U.;Busch, R.;Förstl, H.;Kurz, A., Perneczky, R;Mosch, D;Neumann, M;Kretzschmar, H;Müller, U;Busch, R;Förstl, H;Kurz, A   +9 more
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The Lewy body [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2001
James Parkinson noted: “A diseased state of the medulla spinalis, in that part which is contained in the canal, formed by the superior cervical vertebrae, and extending, as the disease proceeds, to the medulla oblongata . . .is the proximate cause.”1 In the late 19th century, because knowledge of the pathophysiology of the basal ganglia was imprecise,
openaire   +2 more sources

Tau protein, A beta 42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies [PDF]

, 2005
The intra vitam diagnosis of dementia with Lewy bodies (DLB) is still based on clinical grounds. So far no technical investigations have been available to support this diagnosis.
Cepek, L., Neumann, M., Ciesielczyk, Barbara, Cepek, Lukas, Neumann, Manuela, Trenkwalder, C., Kretzschmar, Hans A., Otto, M., Mollenhauer, B., Schulz-Schaeffer, W. J., Poser, Sigrid, Otto, Markus, Ciesielczyk, B., Steinacker, Petra, Steinacker, P., Wiltfang, J., Schulz-Schaeffer, Walter J., Poser, S., Bibl, Mirko, Mollenhauer, Brit, Trenkwalder, Claudia, Bibl, M., Wiltfang, Jens, Kretzschmar, H. A.   +23 more
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Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: Marker candidates for dementia with Lewy bodies [PDF]

, 2007
Background: The measurement of biomarkers in cerebrospinal fluid (CSF) has gained increasing acceptance in establishing the diagnosis of some neurodegenerative diseases.
Steinacker, Petra, Brechlin, Peter, Bahn, Erik, Bibl, Mirko, Locascio, Joseph J., Kretzschmar, Hans A., Mollenhauer, Brit, Trenkwalder, Claudia, Schlossmacher, Michael G., Poser, Sigrid, Otto, Markus, Wiltfang, Jens   +11 more
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Analytical performance and clinical utility of the INNOTEST (R) PHOSPHO-TAU(181P) assay for discrimination between Alzheimer's disease and dementia with Lewy bodies [PDF]

, 2006
Background: Total tau (T-tau) and beta-amyloid((1-42)) (A beta(1-42)) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia.
Bläser, Miriam, Blennow, Kaj,, Vanderstichele, Hugo, Bürger, Katharina, Karen De Vreese, Anari, Lessia, Olsson, Annika Ohrfelt, Miriam Bläser, OLSSON AO, BLASER M, Eugeen Vanmechelen, Harald Hampel, DiLuca, Monica, BURGER K, ANDREASEN N, Christian Sindic, Niels Andreasen, Vanmechelen, Eugeen, Frank Hulstaert, PARNETTI L, LANARI A, VANDERSTICHELE H, Andreasen, Niels, DILUCA M, Katharina Bürger, Pottel, Hans, Öhrfelt Olsson, Annika,, Lanari, Alessia, Parnetti, Lucilla, DE VREESE K, Sindic, Christian, Hulstaert, Frank, Buerger, Katharina, PADOVANI, Alessandro, Monica DiLuca, De Vreese, Karen, Kaj Blennow, Ivanoiu, Adrian, POTTEL H, Padovani, Allesandro, BLENNOW K, Lucilla Parnetti, Annika Ohrfelt Olsson, Hans Pottel, HAMPEL H, Alessia Lanari, Allesandro Padovani, Hampel, Harald, Hugo Vanderstichele, SINDIC C, IVANOIU A, VANMECHELEN E., Blennow, Kaj, HULSTAERT F, Adrian Ivanoiu, Blennow, K, Lanari, A, Parnetti, L, Hampel, H, De, Vreese K, Andreasen, N,, Sindic, C, Vanderstichele, H, Ivanoiu, A, Buerger, K   +64 more
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Gastrointestinal disorders in Parkinson’s disease and other Lewy body diseases

npj Parkinson's Disease, 2023
Parkinson’s disease (PD) is pathologically characterized by the abnormal accumulation of α-synuclein fibrils (Lewy bodies) in the substantia nigra and other brain regions, although the role of Lewy bodies remains elusive.
Masaaki Hirayama, Hiroshi Nishiwaki, Tomonari Hamaguchi, Kinji Ohno   +3 more
doaj   +1 more source

A new visual rating scale for Ioflupane imaging in Lewy body disease

NeuroImage: Clinical, 2018
Background: Dopaminergic loss on 123I-Ioflupane brain imaging is a recognised biomarker for dementia with Lewy bodies. It is usually assessed using a visual rating scale developed for Parkinson's disease, which may not be optimal for dementia with Lewy ...
Jim J. Lloyd, George Petrides, Paul C. Donaghy, Sean J. Colloby, Johannes Attems, John T. O'Brien, Gemma Roberts, Alan J. Thomas   +7 more
doaj   +1 more source

Dementia with Lewy bodies and Parkinson's disease [PDF]

, 2004
Lewy bodies (LB) in the central nervous system are associated with several different clinical syndromes including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Long term follow up of PD patients finds up to 78% eventually develop dementia,
McKeith, Ian G., Mosimann, Urs P.
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Lewy body constipation

Journal of the Anus, Rectum and Colon, 2019
We systematically reviewed literature regarding "Lewy body constipation", i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms. Epidemiology and pathology studies showed that LBD can start with constipation alone, mostly due to neuronal loss and appearance of Lewy bodies in the myenteric plexus. Because LBD significantly
Sakakibara, Ryuji, Doi, Hirokazu, Fukudo, Shin   +2 more
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Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

Molecular Neurodegeneration, 2009
Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas α-synuclein has been found to be the major component of the Lewy body, the mechanisms by which neurons
Perry George, Castellani Rudy J, Takeda Atsushi, Choi Raymond, Kondo Eisaku, Siedlak Sandra L, Chen Shu G, Wang Xinglong, Liu Haihua, Su Bo, Smith Mark A, Zhu Xiongwei, Lee Hyoung-gon   +12 more
doaj   +1 more source