Results 21 to 30 of about 43,190 (257)

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

open access: yesMolecular Neurodegeneration, 2009
Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas α-synuclein has been found to be the major component of the Lewy body, the mechanisms by which neurons
Perry George   +12 more
doaj   +1 more source

Dementia with Lewy Bodies [PDF]

open access: yesSeminars in Neurology, 2014
Dementia with Lewy bodies (DLB) is the second most common diagnosis of dementia after Alzheimer disease (AD). The essential pathologic feature is the Lewy body, a neuronal inclusion containing α-synuclein, found in brainstem nuclei and the neocortex.
Mary Catherine, Mayo, Yvette, Bordelon
openaire   +2 more sources

Dementia with Lewy bodies

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
Te lecture presents modern concept of the symptoms, diagnosis and treatment of dementia with Lewy bodies (DLB), which accounts for about 10% of cases of dementia. Te nosological status of DLB and the problem of ratio of DLB and Parkinson’s disease which,
O. S. Levin   +3 more
doaj   +1 more source

Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium

open access: yesFrontiers in Neurology, 2022
The Lewy Body Dementia Association (LBDA) held a virtual event, the LBDA Biofluid/Tissue Biomarker Symposium, on January 25, 2021, to present advances in biomarkers for Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLBs) and ...
Gregory D. Scott   +54 more
doaj   +1 more source

Effect of Andaliman (Zanthoxylum Acanthopodium DC) Extracts on The Histological Display of Lewy Body in The Brain of Rotenone Induced Wistar Rats

open access: yesInternational Journal of Islamic Education, Research and Multiculturalism
Dementia Lewy Body (DLB) is a form of dementia characterized by abnormal accumulation of α-synuclein protein in the brain, forming lewy bodies that damage the function of neurons and nervous system.
Lubna Afina   +4 more
doaj   +1 more source

Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology

open access: yesNature Communications, 2022
Parkinson’s disease and dementia with Lewy bodies are closely related neurodegenerative disorders, although the epigenetic similarities are not well known.
Lasse Pihlstrøm   +12 more
doaj   +1 more source

Lewy body disease and dementia with Lewy bodies

open access: yesProceedings of the Japan Academy, Series B, 2014
In 1976 we reported our first autopsied case with diffuse Lewy body disease (DLBD), the term of which we proposed in 1984. We also proposed the term "Lewy body disease" (LBD) in 1980. Subsequently, we classified LBD into three types according to the distribution pattern of Lewy bodies: a brain stem type, a transitional type and a diffuse type.
openaire   +3 more sources

More than a rumor spreads in Parkinson’s disease.

open access: yesFrontiers in Human Neuroscience, 2016
As Parkinson's disease progresses, a massive loss of dopaminergic neurons is accompanied by accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies and Lewy neurites.
Natalia Cecilia Prymaczok   +2 more
doaj   +1 more source

Inflammation in dementia with Lewy bodies

open access: yesNeurobiology of Disease, 2022
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of dementia, behind Alzheimer's disease (AD). The profile of inflammation in AD has been extensively researched in recent years, with evidence that chronic peripheral ...
Jay Amin   +11 more
doaj   +1 more source

Common age‐related neuropathologies and yearly variability in cognition

open access: yesAnnals of Clinical and Translational Neurology, 2019
Objective Cognitive variability is a potentially important source of heterogeneity in longitudinal cognitive profiles. We examined the extent to which common age‐related neuropathologies including Lewy bodies and Alzheimer’s disease (AD) contribute to ...
Lei Yu   +6 more
doaj   +1 more source

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