Results 11 to 20 of about 80,148 (202)
Acta Neuropathologica Communications, 2020 Neurons of the nucleus basalis of Meynert (nbM) are vulnerable to Lewy body formation and neuronal loss, which is thought to underlie cognitive dysfunction in Lewy body dementia (LBD).
Christopher Hatton +9 more
doaj +1 more source
Acta Neuropathologica, 2007 The presence of Lewy bodies (LB) in autonomic structures of the central and peripheral nervous system in Parkinson's disease (PD) is well known and could explain clinical signs of pure autonomic failure (PAF) or dysphagia, frequently associated with the disorder.
Kövari, Enikö +3 more
openaire +2 more sources
Lewy body disease or diseases with Lewy bodies?
npj Parkinson's Disease, 2022 The current nosological concept of α-synucleinopathies characterized by the presence of Lewy bodies (LBs) includes Parkinson’s disease (PD), Parkinson’s disease dementia (PDD), and dementia with Lewy bodies (DLB), for which the term “Lewy body disease ...
Kateřina Menšíková +15 more
doaj +1 more source
Progression of extrapyramidal signs in Alzheimer's disease. clinical and neuropathological correlates [PDF]
, 2015 Extrapyramidal signs (EPS) are frequent in Alzheimer's disease (AD) and core manifestation of related diseases, i.e., dementia with Lewy bodies and Parkinson's disease; furthermore, Lewy bodies and AD-type pathology occur in all three ...
Bruno, Giuseppe +4 more
core +1 more source
Reduced Purkinje cell number in essential tremor : a postmortem study [PDF]
, 2008 Background: Clinical and functional imaging evidence suggests that cerebellar dysfunction occurs in essential tremor (ET). In recent postmortem studies, we documented increased numbers of torpedoes (Purkinje cell axonal swellings) in ET patients without ...
Axelrad, Jordan E. +8 more
core +2 more sources
Dementia with Lewy bodies [PDF]
Psychiatry, 1999 Objective: The aim of this paper is to summarise recent clinical and research findings with regard to dementia with Lewy bodies (DLB). Method: A literature review (Medline) was carried out, as well as a review of reports of recent DLB symposia of international meetings and of other relevant papers and data known to the authors.
I, McKeith, J, O'Brien
openaire +12 more sources
Lewy Body Dementia Association\u27s Research Centers of Excellence Program: Inaugural Meeting Proceedings. [PDF]
, 2019 The first Lewy Body Dementia Association (LBDA) Research Centers of Excellence (RCOE) Investigator\u27s meeting was held on December 14, 2017, in New Orleans.
Amodeo, Katherine +44 more
core +3 more sources
Neuropathology and molecular diagnosis of Synucleinopathies
Molecular Neurodegeneration, 2021 Synucleinopathies are clinically and pathologically heterogeneous disorders characterized by pathologic aggregates of α-synuclein in neurons and glia, in the form of Lewy bodies, Lewy neurites, neuronal cytoplasmic inclusions, and glial cytoplasmic ...
Shunsuke Koga +4 more
doaj +1 more source
Gastrointestinal disorders in Parkinson’s disease and other Lewy body diseases
npj Parkinson's Disease, 2023 Parkinson’s disease (PD) is pathologically characterized by the abnormal accumulation of α-synuclein fibrils (Lewy bodies) in the substantia nigra and other brain regions, although the role of Lewy bodies remains elusive.
Masaaki Hirayama +3 more
doaj +1 more source
Phenoconversion from probable rapid eye movement sleep behavior disorder to mild cognitive impairment to dementia in a population-based sample [PDF]
, 2017 © 2017 The Authors Introduction Rapid eye movement sleep behavior disorder (RBD) is strongly associated with synucleinopathies. In 2012, we reported an increased risk of mild cognitive impairment (MCI) and Parkinson disease (PD) in cognitively normal ...
Boeve, Bradley F +11 more
core +2 more sources