Results 51 to 60 of about 80,148 (202)
Young-Onset Dementia with Lewy Bodies
Case Reports in Neurology, 2018 Young-onset (< 65 years) dementia is a challenging clinical problem. A 61-year-old man visited our clinic because of a 2-year history of mild cognitive impairment of the executive disorder type.
Yosuke Aiba +11 more
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Dementia with Lewy Bodies [PDF]
Neurologic Clinics, 2007 The advent of new immunostains have improved the ability to detect limbic and cortical Lewy bodies, and it is evident that dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia, after Alzheimer's disease (AD). Distinguishing DLB from AD has important implications for treatment, in terms of substances that may worsen ...
Tanis J, Ferman, Bradley F, Boeve
openaire +5 more sources
SAGE Open MedicineObjectives: Dementia with Lewy bodies is characterised by rapid fluctuations in attention, which are known as “cognitive fluctuations.” Despite the fact that cognitive fluctuations are considered to be a core dementia with Lewy bodies symptom, they are ...
Ellie Matterson +4 more
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Caspase-Cleaved TAR DNA-Binding Protein-43 in Parkinson’s Disease and Dementia with Lewy Bodies [PDF]
, 2010 Background: TAR DNA-binding protein-43 (TDP-43) proteinopathies are classified based upon the extent of modified TDP-43 and include a growing number of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), frontotemporal lobar ...
Kokoulina, Polina, Rohn, Troy T.
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cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]
, 2015 A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
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Synaptic phosphorylated a-synuclein in dementia with Lewy bodies [PDF]
, 2017 Dementia with Lewy bodies is characterized by the accumulation of Lewy bodies and Lewy neurites in the CNS, both of which are composed mainly of aggregated a-synuclein phosphorylated at Ser129.
Andilla, Jordi +22 more
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Kinematic analysis of handwriting movements in patients with Alzheimer's disease, mild cognitive impairment, depression and healthy subjects [PDF]
, 2003 A variety of studies have demonstrated that motor disorders, parkinsonism and extrapyramidal motor symptoms (EPMS) are common in patients with Alzheimer's disease (AD).
Burger, K. +5 more
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Dementia with Lewy Bodies [PDF]
Seminars in Neurology, 2014 Dementia with Lewy bodies (DLB) is the second most common diagnosis of dementia after Alzheimer disease (AD). The essential pathologic feature is the Lewy body, a neuronal inclusion containing α-synuclein, found in brainstem nuclei and the neocortex.
Mary Catherine, Mayo, Yvette, Bordelon
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Interleukin-1 polymorphisms associated with increased risk of gastric cancer [PDF]
, 2000 Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and ...
A Cox +42 more
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Frederic Lewy: how the two World Wars changed his life, work, and name
Arquivos de Neuro-PsiquiatriaIn 1912, Friedrich Lewy described the inclusion bodies present in Parkinson disease and in Lewy body dementia. Throughout his life, Lewy fought in two wars – on opposite sides.
Patrick Emanuell Mesquita Sousa-Santos +2 more
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