Results 21 to 30 of about 91,122 (346)

Diagnostic Criteria for Dementia with Lewy Bodies: Updates and Future Directions [PDF]

Journal of Movement Disorders, 2020
The aim of this article is to describe the 2017 revised consensus criteria for the clinical diagnosis of dementia with Lewy bodies (DLB) with future directions for the diagnostic criteria.
Masahito Yamada, Junji Komatsu, Keiko Nakamura, Kenji Sakai, Miharu Samuraki-Yokohama, Kenichi Nakajima, Mitsuhiro Yoshita   +6 more
doaj   +1 more source

Neuropathology and molecular diagnosis of Synucleinopathies

Molecular Neurodegeneration, 2021
Synucleinopathies are clinically and pathologically heterogeneous disorders characterized by pathologic aggregates of α-synuclein in neurons and glia, in the form of Lewy bodies, Lewy neurites, neuronal cytoplasmic inclusions, and glial cytoplasmic ...
Shunsuke Koga, Hiroaki Sekiya, Naveen Kondru, Owen A. Ross, Dennis W. Dickson   +4 more
doaj   +1 more source

Non-pharmacological interventions for Lewy body dementia: a systematic review [PDF]

, 2017
Lewy body dementia (consisting of dementia with Lewy bodies and Parkinson's disease dementia) is a common neurodegenerative disease characterised by visual hallucinations, fluctuating attention, motor disturbances, falls, and sensitivity to ...
Michael H. Connors, Lena Quinto, Ian G. McKeith, Henry Brodaty, Louise Allan, Claire Bamford, Alan Thomas, John‐Paul Taylor, John T. O’Brien   +8 more
openalex   +3 more sources

Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT

Programme Grants for Applied Research, 2021
Background: Lewy body dementia, comprising both dementia with Lewy bodies and Parkinson’s disease dementia, is the second commonest cause of neurodegenerative dementia.
John T O’Brien, John-Paul Taylor, Alan Thomas, Claire Bamford, Luke Vale, Sarah Hill, Louise Allan, Tracy Finch, Richard McNally, Louise Hayes, Ajenthan Surendranathan, Joseph Kane, Alexandros E Chrysos, Allison Bentley, Sally Barker, James Mason, David Burn, Ian McKeith   +17 more
doaj   +1 more source

Dementia with Lewy bodies [PDF]

Psychiatry, 1999
Objective: The aim of this paper is to summarise recent clinical and research findings with regard to dementia with Lewy bodies (DLB). Method: A literature review (Medline) was carried out, as well as a review of reports of recent DLB symposia of international meetings and of other relevant papers and data known to the authors.
I, McKeith, J, O'Brien
openaire   +12 more sources

Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis. [PDF]

, 2015
OBJECTIVE: The authors examined research on effects, costs, and patient and caregiver views of pharmacological management strategies for Lewy body dementia.
Cambridge, Victoria, Lafortune, Louise, Mak, Elijah, Mason, James, McKeith, Ian, Mioshi, Eneida, O'Brien, John T, Stinton, Chris, Taylor, John-Paul, Thomas, Alan   +9 more
core   +2 more sources

Alterations in peptide levels in Parkinson's disease and incidental Lewy body disease [PDF]

, 2007
The levels of the neuropeptides Met- and Leu-enkephalin (MET-ENK, LEU-ENK), substance P and neurotensin were measured by a combined high performance liquid chromatography/radioimmunoassay (HPLC/RIA) method in postmortem samples of basal ganglia from ...
Beyer, Cordian, Dang, Jon, Habib, Pardes, Hoffmann, Stefanie, Lammerding, Leoni, Slowik, Alexander, Zendedel, Adib   +6 more
core   +1 more source

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience [PDF]

, 2008
Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying ...
Al-Sarraj, Safa, Alafuzoff, Irina, Arzberger, Thomas, Bogdanovic, Nenad, Budka, Herbert, Capellari, Sabina, Ferrer, Isidro, Gelpi, Ellen, Kovacs, Gabor G., Kovari, Viktor, Kretzschmar, Hans, Nagy, Zoltan, Parchi, Piero, Seilhean, Danielle, Soininen, Hilkka, Troakes, Claire   +15 more
core   +1 more source

Complex I reductions in the nucleus basalis of Meynert in Lewy body dementia: the role of Lewy bodies

Acta Neuropathologica Communications, 2020
Neurons of the nucleus basalis of Meynert (nbM) are vulnerable to Lewy body formation and neuronal loss, which is thought to underlie cognitive dysfunction in Lewy body dementia (LBD).
Christopher Hatton, Amy Reeve, Nichola Zoe Lax, Alasdair Blain, Yi Shiau Ng, Omar El-Agnaf, Johannes Attems, John-Paul Taylor, Doug Turnbull, Daniel Erskine   +9 more
doaj   +1 more source

Lewy Body Disorders [PDF]

Neurologic Clinics, 2017
Dementia syndromes associated with Lewy bodies are subdivided into dementia with Lewy bodies (DLB), an underdiagnosed cause of dementia in the elderly, and Parkinson disease with dementia (PDD), cognitive impairment appearing in people diagnosed with Parkinson disease.
openaire   +2 more sources