Results 41 to 50 of about 72,473 (300)

Music Therapy Techniques for Memory Stabilization in Diverse Dementias [PDF]

, 2018
Music contains certain unmistakable healing properties pertaining specifically to the matured body and soul affected by various types of dementia. Music therapy aids in memory retention or the retarding of the loss of mental function as a result of ...
Shotts, Amanda
core   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Clinical biomarkers for Lewy body diseases

Cell & Bioscience, 2023
AbstractSynucleinopathies are a group of neurodegenerative disorders characterized by pathologic aggregates of neural and glial α-synuclein (α-syn) in the form of Lewy bodies (LBs), Lewy neurites, and cytoplasmic inclusions in both neurons and glia. Two major classes of synucleinopathies are LB disease and multiple system atrophy.
Mai M. Abdelmoaty, Eugene Lu, Rana Kadry, Emma G. Foster, Shaurav Bhattarai, R. Lee Mosley, Howard E. Gendelman   +6 more
openaire   +3 more sources

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Characteristics of facial expression recognition ability in patients with Lewy body disease

Environmental Health and Preventive Medicine, 2018
Background The facial expression of medical staff has been known to greatly affect the psychological state of patients, making them feel uneasy or conversely, cheering them up. By clarifying the characteristics of facial expression recognition ability in
Yuriko Kojima, Tomohiro Kumagai, Tomoo Hidaka, Takeyasu Kakamu, Shota Endo, Yayoi Mori, Tadashi Tsukamoto, Takashi Sakamoto, Miho Murata, Takehito Hayakawa, Tetsuhito Fukushima   +10 more
doaj   +1 more source

Structural connectivity networks in Alzheimer’s disease and Lewy body disease

Brain and Behavior, 2021
Objective We evaluated disruption of the white matter (WM) network related with Alzheimer's disease (AD) and Lewy body disease (LBD), which includes Parkinson's disease and dementia with Lewy bodies.
Kyoungwon Baik, Jin‐Ju Yang, Jin Ho Jung, Yang Hyun Lee, Seok Jong Chung, Han Soo Yoo, Young H. Sohn, Phil Hyu Lee, Jong‐Min Lee, Byoung Seok Ye   +9 more
doaj   +1 more source

Interleukin-1 polymorphisms associated with increased risk of gastric cancer [PDF]

, 2000
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and ...
A Cox, B Ruiz, CA Dinarello, Charles S. Rabkin, Chiu-Chin Yuan, Correa, P., CR Yu, D Basso, DM Parkin, E El-Omar, E El-Omar, EJ Kuipers, EM El-Omar, Emad M. El-Omar, F Pociot, George Lanyon, HC Jung, Howard A. Young, HW Chow, IL Beales, Jay H. Bream, Jesus Herrera, JL Wallace, Jolanta Lissowska, Joseph F. Fraumeni, Kenneth E. L. McColl, LA Noach, LE Hansson, M Carrington, Mary Carrington, Maureen Martin, MJ Blaser, MM Wolfe, NA Tountas, Nathaniel Rothman, P Sipponen, RM Royall, RW Stockbruegger, S Santtila, T Andus, VA Danis, Wong-Ho Chow, Y Yamaoka   +42 more
core   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Early manifestation of depressive‐like behavior in transgenic mice that express dementia with Lewy body‐linked mutant β‐synuclein

Neuropsychopharmacology Reports, 2018
Aim We previously generated transgenic (Tg) mice that expressed P123H β‐synuclein (βS), a dementia with Lewy body‐linked mutant βS. Notably, these mice recapitulated neurodegenerative features of Lewy body disease, reflected by motor dysfunction, greater
Masayo Fujita, Yoko Hagino, Yukio Takamatsu, Yuka Shimizu, Yoshiki Takamatsu, Kazutaka Ikeda, Makoto Hashimoto   +6 more
doaj   +1 more source

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

Molecular Neurodegeneration, 2009
Lewy bodies and Lewy neurites constitute the cardinal neuropathological features of both Parkinson's disease (PD) and Lewy body dementia (LBD). Whereas α-synuclein has been found to be the major component of the Lewy body, the mechanisms by which neurons
Perry George, Castellani Rudy J, Takeda Atsushi, Choi Raymond, Kondo Eisaku, Siedlak Sandra L, Chen Shu G, Wang Xinglong, Liu Haihua, Su Bo, Smith Mark A, Zhu Xiongwei, Lee Hyoung-gon   +12 more
doaj   +1 more source