Results 31 to 40 of about 4,885 (120)
Journal of Biological Chemistry, 1991 The role of Tyr264 in nucleotide binding and hydrolysis catalyzed by the RecA protein of Escherichia coli was investigated by constructing Gly, Ser, and Phe substitution mutations using oligonucleotide-directed mutagenesis. The corresponding mutant recA genes neither restored resistance to killing by ultraviolet irradiation nor increased homologous ...
N E, Freitag, K, McEntee
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Animal Research and One Health, EarlyView.vvrr1, a small RNA, post‐transcriptionally represses the transcriptional regulator LeuO, which directly inhibits the VarS/VarA two‐component system. This triggers a Csr cascade that relieves LuxO repression, ultimately modulating exopolysaccharide production to control biofilm formation and virulence in Vibrio alginolyticus.
Theerakamol Pengsakul +6 more
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Plant Biotechnology Journal, EarlyView.ABSTRACT The single crossover occurring via homologous recombination is a common phenomenon existing among microbes like Escherichia coli, Bacillus subtilis, Vibrio natriegens, Gluconobacter oxydans and most cyanobacteria species, threatening the stability of engineered strains and challenging iterative genetic engineering. Among them, we take the fast‐
Shubin Li +5 more
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Disrupted Gut Viral‐Bacterial Ecology of Patients With Liver Cirrhosis
Liver International, Volume 46, Issue 9, September 2026.ABSTRACT Background The gut microbiota contributes to liver cirrhosis (LC), yet the gut virome and its cross‐kingdom ecology with bacteria are less well defined. Methods To characterize LC‐associated virome alterations and assess their clinical relevance, we reanalyzed publicly available faecal metagenomes from patients with LC and healthy controls ...
Huanhuan Chang +11 more
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Molecular Microbiology, Volume 125, Issue 6, Page 506-545, June 2026.Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang +12 more
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The Plant Journal, Volume 126, Issue 5, June 2026.Significance Statement Life on Earth depends on photosynthetic CO2 fixation via the Calvin–Benson–Bassham cycle to form organic carbon. This process evolved first in cyanobacteria and was later conveyed to eukaryotes, giving rise to plastids in algae and plants. To cope with low atmospheric CO2 concentrations that developed over the course of evolution,
Erik Zimmer +3 more
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Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design
Advanced Science, Volume 13, Issue 14, 9 March 2026.Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao +4 more
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Small Structures, Volume 7, Issue 3, March 2026.This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan +8 more
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Nucleic Acids Research, 1988 The DNA sequences in the operator sites of the arginine regulon and of the SOS regulon have been subject to a statistical analysis. A quantitative correlation is found between the statistics of sequence choice and the activity at individual operator sites in both systems, as expected from theoretical considerations [Berg & von Hippel, J.Mol.Biol. (1987)
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The ZmFKF1b‐ZmDi19‐5 Regulatory Module Coordinates Drought Tolerance and Flowering Time in Maize
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1044-1060, March 2026.ABSTRACT Drought is a major environmental stress that inhibits plant growth and reduces crop yields. The Di19 gene family is known to play a pivotal role in mediating plant responses to drought. However, the mechanisms by which Di19 proteins integrate drought response with developmental processes, particularly flowering time, remain largely unknown in ...
Haixia Zeng +16 more
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