Results 21 to 30 of about 4,885 (120)

Activated RecA protein may induce expression of a gene that is not controlled by the LexA repressor and whose function is required for mutagenesis and repair of UV-irradiated bacteriophage lambda [PDF]

Journal of Bacteriology, 1987
The activated form of the RecA protein (RecA) is known to be involved in the reactivation and mutagenesis of UV-irradiated bacteriophage lambda and in the expression of the SOS response in Escherichia coli K-12. The expression of the SOS response requires cleavage of the LexA repressor by RecA and the subsequent expression of LexA-controlled genes. The
P, Calsou, A, Villaverde, M, Defais
openaire   +2 more sources

UmuDAb: An Error-Prone Polymerase Accessory Homolog Whose N-Terminal Domain Is Required for Repression of DNA Damage Inducible Gene Expression in Acinetobacter baylyi.

PLoS ONE, 2016
In many bacteria, the DNA damage response induces genes (SOS genes) that were repressed by LexA. LexA represses transcription by binding to SOS promoters via a helix-turn-helix motif in its N-terminal domain (NTD).
Travis A Witkowski, Alison N Grice, DeAnna B Stinnett, Whitney K Wells, Megan A Peterson, Janelle M Hare   +5 more
doaj   +1 more source

Bacteriophage 434 Hex Protein Prevents RecA-Mediated Repressor Autocleavage

Viruses, 2013
In a λimm434 lysogen, two proteins are expressed from the integrated prophage. Both are encoded by the same mRNA whose transcription initiates at the PRM promoter. One protein is the 434 repressor, needed for the establishment and maintenance of
Paul Shkilnyj, Michael P. Colon, Gerald B. Koudelka   +2 more
doaj   +1 more source

Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons

Mobile DNA, 2011
Background Integrons are found in hundreds of environmental bacterial species, but are mainly known as the agents responsible for the capture and spread of antibiotic-resistance determinants between Gram-negative pathogens.
Cambray Guillaume, Sanchez-Alberola Neus, Campoy Susana, Guerin Émilie, Da Re Sandra, González-Zorn Bruno, Ploy Marie-Cécile, Barbé Jordi, Mazel Didier, Erill Ivan   +9 more
doaj   +1 more source

Transcriptional analysis of the recA gene of Streptococcus thermophilus

Microbial Cell Factories, 2006
Background RecA is a highly conserved prokaryotic protein that not only plays several important roles connected to DNA metabolism but also affects the cell response to various stress conditions.
Cordone Angelina, Baccigalupi Loredana, Giliberti Gabriele, Ricca Ezio, De Felice Maurilio   +4 more
doaj   +1 more source

Gene expression noise in a complex artificial toxin expression system.

PLoS ONE, 2020
Gene expression is an intrinsically stochastic process. Fluctuations in transcription and translation lead to cell-to-cell variations in mRNA and protein levels affecting cellular function and cell fate. Here, using fluorescence time-lapse microscopy, we
Alexandra Goetz, Andreas Mader, Benedikt von Bronk, Anna S Weiss, Madeleine Opitz   +4 more
doaj   +1 more source

RecA protein-promoted cleavage of LexA repressor in the presence of ADP and structural analogues of inorganic phosphate, the fluoride complexes of aluminum and beryllium

Journal of Biological Chemistry, 1989
Complexes formed from A13+ or Be2+ and fluoride inhibit the single-stranded DNA-dependent ATPase activity of RecA protein. In contrast, poly(dT)-RecA-ADP complexes, which are inactive for cleavage of LexA protein, become fully active in the presence of AlF4- or BeF3- ions.
P L, Moreau, M F, Carlier
openaire   +2 more sources

Stochastic analysis of the SOS response in Escherichia coli.

PLoS ONE, 2009
BackgroundDNA damage in Escherichia coli evokes a response mechanism called the SOS response. The genetic circuit of this mechanism includes the genes recA and lexA, which regulate each other via a mixed feedback loop involving transcriptional regulation
Yishai Shimoni, Shoshy Altuvia, Hanah Margalit, Ofer Biham   +3 more
doaj   +1 more source

MCRS2 represses the transactivation activities of Nrf1

BMC Cell Biology, 2009
Background Nrf1 [p45 nuclear factor-erythroid 2 (p45 NF-E2)-related factor 1], a member of the CNC-bZIP (CNC basic region leucine zipper) family, is known to be a transcriptional activator by dimerization with distinct partners, such as Maf, FosB, c-Jun,
Wu Shan-Fu, Lin Yu-Jen, Yang Chi-Chiang, Lin Young-Sun, Wu Jia-Long, Lin Ying-Ting, Huang Chien-Fu   +6 more
doaj   +1 more source

Genome Wide Mapping of Peptidases in Rhodnius prolixus: Identification of Protease Gene Duplications, Horizontally Transferred Proteases and Analysis of Peptidase A1 Structures, with Considerations on Their Role in the Evolution of Hematophagy in Triatominae

Frontiers in Physiology, 2017
Triatominae is a subfamily of the order Hemiptera whose species are able to feed in the vertebrate blood (i.e., hematophagy). This feeding behavior presents a great physiological challenge to insects, especially in Hemipteran species with a digestion ...
Bianca S. Henriques, Bruno Gomes, Samara G. da Costa, Caroline da Silva Moraes, Rafael D. Mesquita, Rafael D. Mesquita, Viv M. Dillon, Eloi de Souza Garcia, Eloi de Souza Garcia, Patricia Azambuja, Patricia Azambuja, Roderick J. Dillon, Fernando A. Genta, Fernando A. Genta   +13 more
doaj   +1 more source