Results 131 to 140 of about 1,747,583 (341)

trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-α

, 2014
Chunyan Wu, Yaoyao Jia, Ji Hae Lee, Heejin Jun, Hae‐Seung Lee, Kwang-Yeon Hwang, Sung‐Joon Lee   +6 more
openalex   +1 more source

Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer

, 2022
Samman Mansoor, Gülru Kayık, Serdar Durdağı, Özge Şensoy   +3 more
openalex   +1 more source

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.

Proceedings of the National Academy of Sciences of the United States of America, 1998
M. Lambert, A. Barlow, B. Chromy, C. Edwards, R. Freed, M. Liosatos, Todd E. Morgan, I. Rozovsky, B. Trommer, K. Viola, P. Wals, Zhang Chi, C. Finch, G. Krafft, W. Klein   +14 more
semanticscholar   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Synthesis, Characterization and Antibacterial Activity of Mixed Ligand (HL) Complexes Mn(ll), Co(ll), Ni(ll), Zn(ll), Cd(ll) and Hg(ll) with Azide (N<sub>3</sub><sup style="margin-left:-6px;">-</sup>)

, 2015
Jassim S. Sultan, Sajed M. Lateaf, Dhuha K. Rashid   +2 more
openalex   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Bismuth as a Z‐Type Ligand: an Unsupported Pt−Bi Donor‐Acceptor Interaction and its Umpolung by Reaction with H₂ [PDF]

Johannes Schwarzmann, Toni Eskelinen, Sascha Reith, Jacqueline Ramler, Antti J. Karttunen, Jordi Poater, Crispin Lichtenberg   +6 more
openalex   +1 more source

Understanding Ligand‐Directed Heterogeneous Catalysis: When the Dynamically Changing Nature of the Ligand Layer Controls the Hydrogenation Selectivity

, 2021
Carsten Schröder, Marvin C. Schmidt, Philipp A. Haugg, Ann‐Katrin Baumann, Jan Smyczek, Swetlana Schauermann   +5 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source