Results 71 to 80 of about 21,470 (214)
Mechanotransduction via the LINC complex regulates DNA replication in myonuclei [PDF]
Journal of Cell Biology, 2018 Nuclear mechanotransduction has been implicated in the control of chromatin organization; however, its impact on functional contractile myofibers is unclear. We found that deleting components of the linker of nucleoskeleton and cytoskeleton (LINC) complex in Drosophila melanogaster larval muscles abolishes the controlled and synchronized DNA ...
Shuoshuo Wang +6 more
openaire +2 more sources
Maximum population transfer in a periodically driven two-level system [PDF]
, 2014 We study the dynamics of a two-level quantum system under the influence of sinusoidal driving in the intermediate frequency regime. Analyzing the Floquet quasienergy spectrum, we find combinations of the field parameters for which population transfer is ...
Arranz, F. J. +4 more
core +2 more sources
An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells
Advanced Functional Materials, EarlyView.Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio +8 more
wiley +1 more source
Temporal and tissue‐specific disruption of LINC complexes in vivo [PDF]
genesis, 2014 SummaryMigration and anchorage of nuclei within developing and adult tissues rely on Linkers of the Nucleoskeleton to the Cytoskeleton (LINC complexes). These macromolecular assemblies span the nuclear envelope and physically couple chromatin and nuclear lamina to cytoplasmic cytoskeletal networks.
David, Razafsky, Didier, Hodzic
openaire +2 more sources
Advanced Functional Materials, EarlyView.Dicarboxylate‐modified anionic hairy cellulose nanocrystals exhibit a high selectivity for dysprosium(III) over neodymium(III). This selectivity arises from disordered dicarboxylate cellulose “hairs” that enable cooperative ionic coordination, hydrogen bonding, and strain‐induced conformational shrinkage.
Roya Koshani +6 more
wiley +1 more source
mSphere, 2018 Kinetochore clustering, frequently observed in yeasts, plays a key role in genome organization and chromosome segregation. In the absence of the metaphase plate arrangement, kinetochore clustering in yeast species is believed to facilitate timely ...
Vikas Yadav, Kaustuv Sanyal
doaj +1 more source
Advanced Healthcare Materials, EarlyView.PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu +4 more
wiley +1 more source
Nesprin proteins: bridging nuclear envelope dynamics to muscular dysfunction
Cell Communication and SignalingThis review presents a comprehensive exploration of the pivotal role played by the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex, with a particular focus on Nesprin proteins, in cellular mechanics and the pathogenesis of muscular diseases ...
Zhou Zi-yi +4 more
doaj +1 more source
Advanced Materials, EarlyView.We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu +15 more
wiley +1 more source
Focal Spot, Fall/Winter 2010/2011 [PDF]
, 2011 https://digitalcommons.wustl.edu/focal_spot_archives/1115/thumbnail ...
core +1 more source