Results 91 to 100 of about 8,120 (205)

Functional characterization of LINC complex protein assemblies and their role in laminopathies

, 2013
LINC (Linker of nucleoskeleton and cytoskeleton) complexes connect the nucleoskeleton to the cytoskeleton by interactions among LINC complex proteins and their interactions to proteins in the nucleus and the cytosol.
Yang, Liu
core  

Discriminator‐Guided Inverse Folding for Multi‐Property Protein Design

Advanced Science, EarlyView.
Discriminator‐Guided Inverse Folding (DGIF) integrates multiple property predictors trained from single‐property datasets to guide protein sequence generation from a backbone structure. DGIF enables simultaneous improvement of thermostability and solubility without requiring multi‐property annotated datasets and generates designs that move toward the ...
Yuchuan Zheng, Chuyi Liu, Zhaoming Liu, Mao Su, Chenyu Tang, Xiang Zheng, Hao Zhang, Jingyuan Li   +7 more
wiley   +1 more source

Recapitulation of molecular regulators of nuclear motion during cell migration

Cell Adhesion & Migration, 2019
Cell migration is a highly orchestrated cellular event that involves physical interactions of diverse subcellular components. The nucleus as the largest and stiffest organelle in the cell not only maintains genetic functionality, but also actively ...
Alexandra Sneider, Jungwon Hah, Denis Wirtz, Dong-Hwee Kim   +3 more
doaj   +1 more source

Citizenship Concepts in LINC Classrooms

, 2005
In this study we surveyed teachers and program coordinators of Language Instruction for Newcomers to Canada (LINC) from Ontario, British Columbia, and Alberta to determine to what degree they believe they are incorporating citizenship concepts into the ...
Thomson, Ronald I., Derwing, Tracey M.
core   +1 more source

‘Giving Back to Our Community’: The Retention of the Aboriginal and Torres Strait Islander Disability Workforce in New South Wales, Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT The Aboriginal and Torres Strait Islander people of Australia require culturally responsive services. The Australian government has committed to establishing strategies to increase the size of the Aboriginal and Torres Strait Islander disability workforce; however, there is scant research on the factors influencing retention.
J. Gwynn, J. Gilroy, S. Peter, F. Talbot, K. Bulkeley, C. Alcorso, K. Gwynne, B. Rambaldini, A. Haines, M. Lincoln   +9 more
wiley   +1 more source

Sun1 deficiency leads to cerebellar ataxia in mice

Disease Models & Mechanisms, 2015
Migration and organization of the nucleus are essential for the proliferation and differentiation of cells, including neurons. However, the relationship between the positioning of the nucleus and cellular morphogenesis remains poorly understood ...
Jing-Ya Wang, I.-Shing Yu, Chien-Chi Huang, Chia-Yen Chen, Wan-Ping Wang, Shu-Wha Lin, Kuan-Teh Jeang, Ya-Hui Chi   +7 more
doaj   +1 more source

Recent advances in understanding the biological roles of the plant nuclear envelope

Nucleus, 2020
The functional organization of the plant nuclear envelope is gaining increasing attention through new connections made between nuclear envelope-associated proteins and important plant biological processes.
Norman Reid Groves, Alecia Biel, Morgan Moser, Tyler Mendes, Katelyn Amstutz, Iris Meier   +5 more
doaj   +1 more source

Development and Characterization of ZnO‐Filled and Maleic Anhydride‐Compatibilized PP/SEBS Blends for 3D‐Printing Filaments

Journal of Applied Polymer Science, EarlyView.
PP/SEBS/MA/ZnO filaments produced by bench‐top single‐screw extrusion show refined morphology, increased crystallinity, improved thermal robustness, and preliminary FFF printability, demonstrating a practical route for functional filament development. ABSTRACT Currently, single‐screw extrusion offers a versatile and accessible route to produce polymer ...
Chiara das Dores do Nascimento, Cesar Aguzzoli, Everton Granemann Souza, Ana Cristina Beitia Kraemer Moraes, Fabricio Celso, Patricia Oliveira Schmitt, Lincoln Audrew Cordeiro, Fernanda Langone, Marlon Bender Bueno Rodrigues, Luana Vaz Tholozan, Neftali Lenin Villarreal Carreno, André Luiz Missio, Amanda Dantas de Oliveira   +12 more
wiley   +1 more source

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

, 2017
Mechanical integration of the nucleus with the extracellular matrix (ECM) is established by linkage between the cytoskeleton and the nucleus. This integration is hypothesized to mediate sensing of ECM rigidity, but parsing the function of nucleus ...
Roux, Kyle J., Aggarwal, Varun, Shrestha, Shristi, Jones, Angela L., Kuchibhotla, Ram, Zhang, Qiao, Nickerson, Jeffrey A., Li, Yuan, Alam, Samer G., Lele, Tanmay P., Prasad, Nripesh, Levy, Shawn E., Kc, Birendra, Chamala, Srikar   +13 more
core   +1 more source

The LINC complex in blood vessels: from physiology to pathological implications in arterioles

© 2025 The Authors. The Journal of Physiology © 2025 The Physiological Society.The LINC (linker of nucleoskeleton and cytoskeleton) complex is a critical component of the cellular architecture that bridges the nucleoskeleton and cytoskeleton and mediates
Ferreira G., Santander A., Sobrevia Luarte, Luis Alberto, Cardozo R., Chavarria L., Chang W., Nicolson G.L., Gundersen G.   +7 more
core   +2 more sources