Results 51 to 60 of about 8,120 (205)
eLife, 2023 Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via regulation of cell-cell junctions.
Danielle B Buglak +16 more
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LINC complex alterations in DMD and EDMD/CMT fibroblasts [PDF]
European Journal of Cell Biology, 2012 Emery-Dreifuss muscular dystrophy (EDMD) is a late onset-disease characterized by skeletal muscle wasting and heart defects with associated risk of sudden death. The autosomal dominant form of the disease is caused by mutations in the LMNA gene encoding LaminA and C, the X-linked form results from mutations in the gene encoding the inner nuclear ...
Taranum, Surayya +8 more
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Birth of a Regulatory Long Non-coding RNA/Gene, linc-UR-UB
Frontiers in Genetics, 2021 The origin of genes has been a major topic of research for many years, albeit in some cases, it has been a difficult process to elucidate. Insightful is a recent publication that experimentally shows how one gene, linc-UR-UB was born.
Nicholas Delihas
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Cells, 2020 Vascular smooth muscle cells (VSMCs) are the predominant cell type in the blood vessel wall. Changes in VSMC actomyosin activity and morphology are prevalent in cardiovascular disease. The actin cytoskeleton actively defines cellular shape and the LInker
Lauren Porter +12 more
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Nucleus, 2019 The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along with specialized ...
Hardeep K. Gumber +6 more
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Role of KASH domain lengths in the regulation of LINC complexes [PDF]
Molecular Biology of the Cell, 2019 The linker of the nucleoskeleton and cytoskeleton (LINC) complex is formed by the conserved interactions between Sad-1 and UNC-84 (SUN) and Klarsicht, ANC-1, SYNE homology (KASH) domain proteins, providing a physical coupling between the nucleoskeleton and cytoskeleton that mediates the transfer of physical forces across the nuclear envelope.
Jahed, Zeinab +10 more
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LINC complex: The link between chromatin integrity and sperm motility
, 2022 The LINC complex (Linker of the Nucleoskeleton and Cytoskeleton) is a protein structure located in the nuclear membrane that connects the cytoskeleton with the nucleoskeleton.
Šanovec, Ondřej
core
Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD
Nature Communications, 2017 Long non-coding RNAs (lncRNAs) are important regulators of diverse biological processes. Here we report on functional identification and characterization of a novel long intergenic non-coding RNA with MyoD-regulated and skeletal muscle-restricted ...
Xiaohua Yu +15 more
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Mechanical Characterization of Glandular Acini Using a Micro-indentation Instrument
Bio-Protocol, 2020 The linker of nucleoskeleton and cytoskeleton (LINC) complex is responsible for tethering the nucleus to the cytoskeleton, providing a pathway for the cell’s nucleus to sense mechanical signals from the environment.
Christopher O'Bryan +3 more
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Chain reaction: LINC complexes and nuclear positioning [PDF]
F1000Research, 2019 Nuclear positioning plays an essential role in defining cell architecture and behaviour in both development and disease, and nuclear location frequently adjusts according to internal and external cues. For instance, during periods of migration in many cell types, the nucleus may be actively repositioned behind the microtubule-organising centre. Nuclear
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