Results 131 to 140 of about 291,117 (255)

Deep learning for dose-averaged linear energy transfer estimation in pencil-beam scanning and double scattering proton radiotherapy plans with uncertainty-aware external validation. [PDF]

Phys Imaging Radiat Oncol
Kieslich A, Singh Y, Palkowitsch M, Starke S, Hennings F, Troost EGC, Krause M, Bensberg J, Lühr A, Heinzelmann F, Bäumer C, Timmermann B, Depauw N, Shih HA, Löck S.   +14 more
europepmc   +1 more source

Interaction of curcumin with glioblastoma cells via high and low linear energy transfer radiation therapy inducing radiosensitization effects. [PDF]

J Radiat Res, 2022
Kim JY, Jung CW, Lee WS, Kim HJ, Jeong HJ, Park MJ, Jang WI, Kim EH.   +7 more
europepmc   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Dual-storage phosphor proton therapy dosimetry: Simultaneous quantification of dose and linear energy transfer. [PDF]

Med Phys, 2021
Setianegara J, Mazur TR, Yang D, Li HH.
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Reduced beam time and distal linear energy transfer with mini-ridge filters in pencil beam scanning proton therapy. [PDF]

Phys Imaging Radiat Oncol
O'Grady F, Stephenson L, Janson M, Rao AD, Chawla AK, Fan J, Wang P.   +6 more
europepmc   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

Unravelling the impact of linear energy transfer on micronuclei induction from proton and photon irradiation. [PDF]

Sci Rep
Heaven CJ, Warmenhoven JW, Chadwick AL, Santina E, Honeychurch J, Schmidt CK, Kirkby KJ, Merchant MJ, Henthorn NT.   +8 more
europepmc   +1 more source

Evaluation of radiophotoluminescent glass dosimeter response for therapeutic spot scanning proton beam: suggestion of linear energy transfer-based correction. [PDF]

J Appl Clin Med Phys, 2021
Nagata J, Yasui K, Omachi C, Toshiyuki T, Shimizu H, Aoyama T, Hayashi N.   +6 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source