Results 131 to 140 of about 63,855 (231)

Linezolid-Induced Pure Red Cell Aplasia: A Case Report

, 2022
Xiao-Yan Yang, Lin Chen, Ji-Na Gu, Cheng-Jun Zeng, Dan-Mei Pan Infectious Diseases Department, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, 315010, People’s Republic of ChinaCorrespondence: Lin Chen, Infectious Diseases department,
Pan DM, Zeng CJ, Chen L, Gu JN, Yang XY
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A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih, Anguraj Moulishankar, Chee Yan Choo, Khang Wen Goh, Chrismawan Ardianto, Azam Che Idris, Long Chiau Ming   +6 more
wiley   +1 more source

Population Pharmacokinetic/Pharmacodynamic Study of Linezolid in Hospital-Acquired Pneumonia Patients with Renal Insufficiency [PDF]

Jin-hui Xu,1,* Xiang-long Chen,1,* Qian Zhang,1,* Zhiwei Zhuang,2 Yun-long Yuan,3 Lu-fen Duan,1 Lu Shi,1 Chenqi Zhu,1 Jing-Jing Li,1 Jian Lu,4 Yan-xia Yu,1 Lian Tang1,5 1Department of Pharmacy, The Affiliated Suzhou Hospital of Nanjing Medical University,
Duan L, Shi L, Li J, Tang L, Lu J, Chen X, Xu J, Zhang Q, Zhuang Z, Yuan Y, Zhu C, Yu Y   +11 more
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Phenotypic Investigation of Vancomycin, Teicoplanin and Linezolid Resistance Among Enterococcus spp. Isolated from Children Diarrhea

, 2019
Vancomycin-resistant Enterococci(VRE) were common among Enterococcus. faecalis and Enterococcus faecium. Teicoplanin resistance or sensitivity can determine the VRE phenotypes whether VanA (VanR/TecR) or VanB (VanR/TecS). Linezolid resistance among VRE
Mohammed Sh. Jebur, Anwar M. Lazm, Hussein W. S. Rabeea, Mohammed H. Al-Allak, Ali Saleem Abdulridha Aridhee, Noor S. K. Al-Khafaji, Hussein O. M. Al-Dahmoshi   +6 more
core   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

Hemodialysis International, Volume 30, Issue 4, Page 679-688, October 2026.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra, Jordan Fangue‐Nelon, Garima Singh   +2 more
wiley   +1 more source

The Effect of Linezolid Therapy Duration on The Occurrence of Toxic Optic Neuropathy

Aksona
Highlight: • The occurence of toxic optic neuropathy in this study was similar to the occurence of anemia. • Discontinuation of Linezolid therapy improves visual disturbance • Linezolid therapy duration to cause TON in this study varies ...
Quinamora Estevan Sutantyo, Lukisiari Agustini, Tutik Kusmiati, Ariani Permatasari   +3 more
doaj   +1 more source

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, Volume 37, Issue 5, Page 581-591, October 2026.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

Clinical update on linezolid in the treatment of Gram-positive bacterial infections

, 2012
Sally Ager, Kate GouldDepartment of Microbiology, Newcastle upon Tyne Hospitals Trust, Freeman Hospital, High Heaton, Newcastle upon Tyne, UKAbstract: Gram-positive pathogens are a significant cause of morbidity and mortality in both community and health
Ager S, Gould K
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High accumulation of linezolid and its major metabolite in the serum of patients with hepatic and renal dysfunction is significantly associated with thrombocytopenia and anemia

Microbiology Spectrum
This study aims to examine the serum levels of linezolid and its metabolites (PNU-142300 and PNU-142586) in patients with varying hepatic and renal function.
Junqiang Gou, Qian Li, Ning Fan, Chen Zhang, Haiwen Tang, Xiaofeng Wang, Dongfeng Yin   +6 more
doaj   +1 more source

Linezolid resistant Staphylococcus aureus [PDF]

, 2017
Linezolid is the only antibiotic available as an oral formulation for resistant staphylococcal infections. It is effective in skin & soft tissue infections, nosocomial pneumonias including VAP, infective endocarditis and MRSA meningitis.
Gandham, Pavani
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