Results 111 to 120 of about 41,061 (224)

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu, Shuqing Ma, Fen Xu, Xiangmin Han, Ming Li, Yuanqi Zhu, Sufei Pan, Sujun Hou, Chunqing Ma, Fawen Deng, Shifu Wang, the SPARSS net Working Group, Ningning Ge, Fen Su, Renzhe Li, Fengyan Pei, Chunhua Han, Chengjie Guo, Mingju Hao, Bin Ji, Yan Sun, Xiulei Xue, Mingyan Sun, Yilei Li, Hongyun Cao, Hong He, Fang Wang, Zheng Zhou, Xiaoling Zan, Weiping Zhou, Xuejiao Leng, Chunzhong Dong, Xu Zheng, Shiying Sun, Wei Li, Yongjuan Ma, Jin Li, Xiao‐ying Li, Hongyan Bi, Jinjing Tian, Zhiyong Zhang, Ruifang Yang, Yulong Dai, Xuerong Sun, He Yi, Bo Yu, Fengzhi Bian, Qin Yi, Haiying Chen, Qingling Liu, Guixia Li, Jinfang Guo, Hongning Zhang, Huili Hou, Tao Chen, Zhiwei Liu, Ping Wu, Jiajia Feng, Li‐e Zhang, Junjie Dai, Jie Chen   +60 more
wiley   +1 more source

Characterization of linezolid- and methicillin-resistant coagulase-negative staphylococci in a tertiary hospital in China

BMC Infectious Diseases
Background Recently, linezolid-resistant staphylococci have become an emerging problem worldwide. Understanding the mechanisms of resistance, molecular epidemiology and transmission of linezolid-resistant CoNS in hospitals is very important.
Cailin Liu, Jing Yu, Chunguang Chen, Xiaogai Li, Yafei Ye, Yani Dong, Xinxin Ying, Haijun Li, Wanhai Wang   +8 more
doaj   +1 more source

N-TERMINAL PROCESSING OF RIBOSOMAL PROTEIN L27 IN STAPHYLOCOCCUS AUREUS [PDF]

, 2012
The bacterial ribosome is essential to cell growth yet little is known about how its proteins attain their mature structures. Recent studies indicate that certain Staphlyococcus aureus bacteriophage protein sequences contain specific sites that may be ...
Caufield, J. Harry
core   +1 more source

A new oxazolidinone antimicrobial [PDF]

, 2014
Purpose. The mechanism of action, pharmacokinetics, pharmacodynamics, and clinical efficacy and safety of an investigational second-generation oxazolidinone are reviewed. Summary. Tedizolid is a protein synthesis inhibitor in clinical development for the
Childs, Lindsay M,, Kisgen, Jamie J., Mansour, Hanine, Unger, Nathan R.   +3 more
core   +1 more source

Genomic Insights Into a Hospital‐Acquired High‐Risk Vancomycin‐Resistant Enterococcus faecium Outbreak in Guangdong, China

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
We characterized a dominant ST80 clone responsible for a vancomycin‐resistant Enterococcus faecium outbreak in Chinese hospitals, revealing its close genetic ties to global lineages. A novel PCR method was developed for targeted surveillance of this high‐risk strain. ABSTRACT A comprehensive molecular epidemiological study was conducted on a vancomycin‐
Yang Guo, Chuyue Zhuo, Tianxin Zhang, Kuihai Wu, Zhengqi Shi, Yan Zhu, Jiayuan Huang, Chao Zhuo, Nan Qi   +8 more
wiley   +1 more source

Antimicrobial susceptibility patterns of Linezolid-resistant coagulase-negative staphylococci in Pakistan

Khyber Medical University Journal
OBJECTIVE: To determine the antimicrobial resistance pattern in Linezolid-resistant coagulase negative staphylococcus (CoNS) isolates in Pakistan. METHODS: This cross-sectional study was conducted from February and July 2022, at a private laboratory in
Arooj Sattar, Namra Mahmood, Zahra Riaz, Iram Yousaf, Rubeena Hafeez, Sakina Jamil   +5 more
doaj   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Evaluating Dog Bite‐Induced Facial Trauma: A Study From a Single Tertiary Care Center

OTO Open, Volume 10, Issue 2, April-June 2026.
Abstract Objective Analyze demographic and clinical factors for patients presenting with dog bites to the face, head, or neck. Study Design Retrospective cohort. Setting Single tertiary care, level 1 trauma center. Methods A retrospective chart review identified patients presenting for facial dog bite injuries from 2012 to 2023.
Andrew J. Rothka, Marly Aziz, Katelyn P. K. Nguyen, F. Jeffrey Lorenz, Heather K. Schopper, Jessyka G. Lighthall   +5 more
wiley   +1 more source

Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]

, 2013
Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill, A Koul, AE Grzegorzewicz, Alfonso Mendoza-Losana, Anil Kumar Tyagi, C Dye, C Varela, Carlos Alemparte, Carolina González, Chrystala Constantinidou, CK Stover, David Barros, David J. Dow, DJ Payne, Douglas J. Minick, Elena Jiménez, Esther Pérez-Herrán, Fátima Ortega-Muro, Gurdyal S. Besra, Iñigo Angulo-Barturen, JA Maddry, Joaquín Rullás, Johnson Afari, Jorge Esquivias, K Andries, K Pethe, K Tahlan, LL Ballell, Lluís Ballell, M Berry, M Biava, M Murray, M Protopopova, Mark J. Pallen, María José Rebollo-López, María Martínez-Hoyos, María Teresa Fraile-Gabaldón, Modesto J. Remuiñán, Mónica Cacho, Nalini Mehta, Nicholas Cammack, Nicholas J. Loman, R Singh, SA Stanley, ST Cole, V La Rosa, V Makarov, Verónica Sousa, Vickey L. Spivey   +48 more
core   +3 more sources

DILIConsult: A Multi‐Agent Large Language Model Framework for Evaluating Drug‐Induced Liver Injury in ICU Settings

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 4, April 2026.
ABSTRACT Background Large language models (LLMs) can support clinical decision‐making by parsing databases and extracting relevant information. However, evaluating drug‐induced liver injury (DILI) often requires processing lengthy clinical histories alongside reference materials like LiverTox, which can exceed context lengths of conventional LLMs ...
Alfred Zheng Ting Ho, Jeren Zheng Feng Law, Aiwen Wang, Daniel Yan Zheng Lim, Jasmine Chiat Ling Ong   +4 more
wiley   +1 more source