Results 91 to 100 of about 41,061 (224)

Allium‐Derived Compounds Against Multidrug‐Resistant Bacteria: Antibacterial Activity and Synergistic Effects

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
This study evaluates four compounds derived from the genus Allium against 330 multidrug‐resistant bacteria. Propyl‐propane‐thiosulfonate (PTSO) exhibits the highest activity, particularly against Gram‐positive strains, while Gram‐negative bacteria are less affected.
Antonio Sorlózano‐Puerto, Yariel Figueroa‐Vega, Pablo Martín‐Valenzuela, José Manuel de la Torre‐Ramírez, Alberto Baños, José Gutiérrez‐Fernández   +5 more
wiley   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi, Ami G. Shah, Anderson, Arlt, Barr, Barthelemy, Beiderlinden, Bein, Bembea, Bhatt-Meht, Boucher, Brandi N. Thoma, Brown, Buck, Buscher, Chung, Dagan, Dagan, de Montmollin, De Rosa, DeGrado, Donadello, Donadello, Dzierba, Erstad, Esper, Eyler, Flordelis Lasierra, Glauber, Greenberg, Gélisse, Hadidi, Hertzog, Hraiech, Hynynen, Johnston, Kawada, Kim, Koster, Krueger, Lamarche, Latronico, Lemaitre, Levison, Malfertheiner, Mehta, Michelle Peahota, Moore, Mousavi, Mulla, Mulla, Muntean, Oliver, Paden, Park, Perkins, Peters, Pettignano, Phillips, Pieri, Potter, Preston, Protti, Ranucci, Riker, Roberts, Roos, Rosen, Ruiz, Rybak, Saini, Sanfilippo, Satyapriya, Schmith, Shekar, Shekar, Shekar, Shekar, Shekar, Sherwin, Sklar, Smith, Spriet, Staudacher, Strunk, Subramaniam, Szefner, Tellor, Trudzinski, Tulman, Turner, Veinstein, Vilay, Wagner, Walter K. Kraft, Welsch, Wen, Wildschut, Wu, Young   +99 more
core   +2 more sources

Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm

Journal of Global Antimicrobial Resistance, 2020
Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Susana Sanz, Carmen Olarte, Inga Eichhorn, Stefan Schwarz, Carmen Torres   +7 more
doaj   +1 more source

Successful Intra-peritoneal Antibiotic Therapy for Primary Abdominal Nocardiosis in an Immunocompetent Young Female Masquerading as Carcinoma Ovary [PDF]

, 2012
Nocardiosis is a common opportunistic infection in the immunocompromised and in patients with chronic debilitating diseases,e.g continuous ambulatory peritoneal dialysis (CAPD) patients.
Bafna, UD, Pallavi, VR, Patil, RN, Rathod, PS   +3 more
core  

Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017 [PDF]

, 2018
Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms.
Aghdassi, S., Alberg, T., Arendt, V., Arvaniti, K., Asensio, A., Berg, T. C., Berger-Carbonne, A., Borg, M. A., Bosnjak, Z., Budimir, A., Burns, K., Cairns, S., Cantero, M., Daniau, C., Debacker, M., Deptula, A., Dimina, E., Dobreva, E., Dragovac, G., Florentin, D., Gastmeier, P., Gibbons, C., Gudlaugsson, O., Hadjihannas, L., Hajdu, A., Hansen, S., Harrison, W., Hopkins, S., Hopmans, T., Hristova, R., Ivanov, I. N., Jindrak, V., Johnson, A., Karki, T., Kinross, P., Kontopidou, F., Korosec, A., Latour, K., Litvova, S., Lyytikainen, O., Markovic-Denic, L., Martin, P., McConaghy, M., Mitt, P., Monnet, D. L., Moro, M. L., Nedyalkov, M., Neves, I., Niculcea, A. S., Pacheco, P., Plachouras, D., Presterl, E., Quattrocolo, F., Reilly, J., Rydygier, L., Sartaj, M., Sarvikivi, E., Serban, R. I., Smid, E., Staniulyte, J., Stefkovicova, M., Strauss, R., Suetens, C., Vandael, E., Vilde, A., Weist, K., Zarb, P., Zingg, W., Zotti, C. M., Zupanc, T. L.   +69 more
core   +7 more sources

European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria [PDF]

, 2020
Background Antimicrobial resistance (AMR) compromises the treatment of patients with serious infections in intensive care units (ICUs), and intensive care physicians are increasingly facing patients with bacterial infections with limited or no adequate ...
De Waele, Jan, Friggeri, Arnaud, Garnacho-Montero, José, Gustin, Marie Paule, Jean, Astrid, Kohlenberg, Anke, Lepape, Alain, Monnet, Dominique L., Savey, Anne, Vanhems, Philippe   +9 more
core   +2 more sources

Effect of daptomycin and vancomycin on Staphylococcus epidermidis biofilms: An in vitro assessment using fluorescence in situ hybridization [PDF]

, 2019
Colonization of in-dwelling catheters by microbial biofilms is a major concern in patient health eventually leading to catheter-related blood stream infections.
Affeld, Klaus, Gabel, Grischa, Gebhardt, M., Goubergrits, Leonid, Kertzscher, Ulrich, Kikhney, Judith, Kursawe, Laura, Moter, Annette, Petrich, A., Schmidt, Julia, Sutrave, Smita, Wiessner, Alexandra   +11 more
core   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Linezolid‐mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition

Arthritis &Rheumatology, Volume 78, Issue 4, Page 914-927, April 2026.
Objective Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H. W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Influence of real-world characteristics on outcomes for patients with methicillin-resistant Staphylococcal skin and soft tissue infections:a multi-country medical chart review in Europe [PDF]

, 2014
BACKGROUND: Patient-related (demographic/disease) and treatment-related (drug/clinician/hospital) characteristics were evaluated as potential predictors of healthcare resource use and opportunities for early switch (ES) from intravenous (IV)-to-oral ...
A Gray, AD Tice, AL Chapman, BA Cunha, BA Lipsky, C Eckmann, C Eckmann, Caitlyn T Solem, Christian Eckmann, Cynthia Macahilig, D Nathwani, D Nathwani, DA Goff, Damien Simoneau, Dilip Nathwani, HS Sader, HT Hatoum, J Edelsberg, Jennifer M Stephens, Jim Z Li, KB Bamford, M Borner, M Desai, M Dryden, M Hensher, P Mladovsky, PC Matthews, RA Seaton, Richard Chambers, S Leekha, S Parodi, SC Lim, Seema Haider, Shelby Corman, TH Dellit, Wendy Lawson   +35 more
core   +4 more sources