Results 91 to 100 of about 2,219,397 (166)

Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro

Infection and Drug Resistance
Tala Han,1 Ting Jia,1 Junrui Wang1,2 1Department of Laboratory Medicine, Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China; 2Inner Mongolia Key Laboratory of Clinical Pathogenic Microorganism, The ...
Han T, Jia T, Wang J
doaj  

Emergence of linezolid resistant Staphylococcus aureus in Bastar tribal region, India [PDF]

Journal of Microbiology and Infectious Diseases, 2012
Methicillin resistant Staphylococcus aureus(MRSA) is a well-known threat to the healthcaresystems for its increasing global prevalence, intrinsicability of resistance to ß-lactam and cephalosporin,and for acquiring resistance to multipleclasses of other ...
Mohammad Fareed Khan, Arvind Neral, Vikas Chandra Yadav, Farah Aziz Khan, Sarfaraz Ahmed   +4 more
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A cfr-positive clinical staphylococcal isolate from India with multiple mechanisms of linezolid-resistance [PDF]

, 2014
Background & objectives: Linezolid, a member of the oxazolidinone class of antibiotics, has been an effective therapeutic option to treat severe infections caused by multidrug resistant Gram positive bacteria.
Kumar, V. G. S., Shubha Gopal, Rajan, V.
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Differences in oxazolidinone resistance mechanisms and small colony variants emergence of Staphylococcus aureus induced in an in vitro resistance development model

Emerging Microbes and Infections
Invasive Staphylococcus aureus infections are associated with a high burden of disease, case fatality rate and healthcare costs. Oxazolidinones such as linezolid and tedizolid are considered potential treatment choices for conditions involving ...
Moritz Staudacher, Julian Frederic Hotz, Richard Kriz, Katharina Schefberger, Lisa Schneider, Kathrin Spettel, Peter Starzengruber, Jürgen Benjamin Hagemann, Amelie Leutzendorff, Heinz Burgmann, Heimo Lagler   +10 more
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Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy

Linezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid
Sierra, Josep M., Martin, Rogelio, Tubau, Fe, Gasch, Oriol, Camoez, Mariana, Domínguez Luzón, Ma. Ángeles (María Ángeles), Pujol Rojo, Miquel   +6 more
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Epidemiological characteristics and genetic structure of linezolid-resistant Enterococcus faecalis

, 2018
Meijuan Chen,1 Hongying Pan,1 Yaling Lou,2 Zhe Wu,3 Jiajie Zhang,1 Yicheng Huang,1 Wei Yu,1,3,* Yunqing Qiu3,* 1Department of Infectious Diseases, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou,
Pan H, Qiu Y, Wu Z, Huang Y, Zhang J, Chen M, Lou Y, Yu W   +7 more
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cfr and optrA gene based characterization of linezolid resistant Staphylococcus haemolyticus in a tertiary care hospital in western Uttar Pradesh, India [PDF]

Journal of Krishna Institute of Medical Sciences University
Background: Staphylococcus haemolyticus is a clinically significant Coagulase Negative Staphylococci (CoNS) accountable for various infections and is often multi-drug resistant along with resistance to linezolid.
Km. Sangita, Geeta Gupta, Anita Pandey, Ankita Gupta   +3 more
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Antimicrobial agents against vancomycin-resistant enterocci (Linezolid)

, 2002
Linezolid（LZD）は米国ファルマシア・アップジョン社で合成されたoxazolidinone 骨格を有する薬剤であり，30 年ぶりに新しい分類に属する抗菌薬として開発されている。LZD は50 S サブユニットのドメインV に特異的に結合することにより，50 S リボゾーム，30 S リボゾーム，m.RNA およびf.Met.t.RNA からなる開始複合体の形成を阻害する。その結果，既存の抗菌薬と異なり，蛋白合成の開始を抑制することにより抗菌力を発揮する。LZD は，メチシリン耐性黄色ブドウ球菌（
壼原, 克紀, 河野, 茂
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Linezolid resistant Staphylococcus aureus [PDF]

, 2017
Linezolid is the only antibiotic available as an oral formulation for resistant staphylococcal infections. It is effective in skin & soft tissue infections, nosocomial pneumonias including VAP, infective endocarditis and MRSA meningitis.
Gandham, Pavani
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Proteomic and Transcriptomic Analysis of Linezolid Resistance in Streptococcus pneumoniae

, 2016
Linezolid is an oxazolidinone antibiotic that inhibits the initiation of translation. Although resistance to linezolid is an uncommon event, it has been reported in clinical isolates.
Jie Feng (8115), Andréanne Lupien (2163211), Eric Winstall (36419), Danielle Légaré (2163208), Marc Ouellette (51263), Dewan S. Billal (2163214), Philippe Leprohon (133682), Gina Racine (834509)   +7 more
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