Results 81 to 90 of about 2,219,397 (166)

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, Volume 37, Issue 5, Page 581-591, October 2026.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

Wide dissemination of linezolid-resistant Staphylococcus epidermidis in Greece is associated with a linezolid-dependent ST22 clone

, 2014
Objectives: Dependence on linezolid was recently described as significant growth acceleration of linezolidresistant Staphylococcus epidermidis (LRSE) isolates upon linezolid exposure.
Kimouli, M., Tsakris, A., Kousouli, E., Poulou, A., Ntokou, E., Hadjichristodoulou, C., Kristo, I., Carle, P., Kouskouni, E., Mamali, V., Vrioni, G., Dafopoulou, K., Papagiannakopoulou, P., Papanikolaou, P., Tsorlini, E., Themeli-Digalaki, K., Pournaras, S., Nepka, M., Stathoulopoulou, F., Stathopoulos, C., Zarkotou, O., Foudoulis, K., Karavasilis, V., Gennimata, V., Greek Study Group on Staphylococcal Linezolid Resistance, Kachrimanidou, M., Panopoulou, M., Stylianakis, A., Perivolioti, E.   +28 more
core   +1 more source

Optimising linezolid use for drug-resistant tuberculosis: pharmacokinetics, toxicity, and resistance [PDF]

, 2022
Background: Rifampicin-resistant tuberculosis (RR-TB) accounts for an expanding proportion of incident global TB cases and is a major barrier to global tuberculosis control. There is a need for more effective, safe, and well-tolerated drugs. Linezolid is
Wasserman, Sean Adam
core  

Occurrence of cfr-Positive Linezolid-Susceptible Staphylococcus aureus and Non-aureus Staphylococcal Isolates from Pig Farms

, 2023
The emergence and spread of cfr-mediated resistance to linezolid in staphylococci have become a serious global concern. The acquisition of cfr confers multidrug resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A ...
Soo-Jin Yang, Gi Yong Lee
core   +1 more source

Genomic characteristics of cfr and fexA carrying Staphylococcus aureus isolated from pig carcasses in Korea

Veterinary Research
The emergence of transferable linezolid resistance genes poses significant challenges to public health, as it does not only confer linezolid resistance but also reduces susceptibility to florfenicol, which is widely used in the veterinary field.
Eiseul Kim, Seung-Min Yang, Hyo-Sun Kwak, Bo-Youn Moon, Suk-Kyung Lim, Hae-Yeong Kim   +5 more
doaj   +1 more source

Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome [PDF]

, 2012
Linezolid is an oxazolidinone antibiotic in clinical use for the treatment of serious infections of resistant Gram-positive bacteria. It inhibits protein synthesis by binding to the peptidyl transferase center on the ribosome. Almost all known resistance
Katherine S. Long, Birte Vester, Long, Katherine S, Long, Katherine S., Vester, Birte   +4 more
core   +1 more source

Linezolid-resistant mucoid Staphylococcus haemolyticus from a tertiary-care centre in Delhi

New Microbes and New Infections, 2016
We report an unusual morphological mucoid variant of Staphylococcus haemolyticus associated with linezolid resistance from a patient with sepsis. Linezolid resistance and mucoid character together made this pathogen difficult to treat.
M. Matlani, T. Shende, V. Bhandari, R. Dawar, R. Sardana, R. Gaind   +5 more
doaj   +1 more source

Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations [PDF]

, 2011
Background Several mutations were present in the genome of Streptococcus pneumoniae linezolid-resistant strains but the role of several of these mutations had not been experimentally tested.
Jie Feng, Billal Dewan S, Danielle Légaré, Marc Ouellette, Philippe Leprohon, Légaré Danielle, Leprohon Philippe, Feng Jie, Ouellette Marc, Dewan S Billal   +9 more
core   +2 more sources

Construction of a linezolid-resistant strain of methicillin-susceptible Staphylococcus aureus and its multi-omics based mechanism study

Frontiers in Cellular and Infection Microbiology
BackgroundThe emergence of linezolid−resistant methicillin−susceptible Staphylococcus aureus (MSSA) is a growing clinical threat, but the underlying mechanisms are unclear.
Wei Zhang, Linhui Huang, Yanye Tu, Feng Wang, Hong Li, Yanzi Chang, Xudong Feng, Jie Zhou   +7 more
doaj   +1 more source

Epidemiology and genetic diversity of linezolid-resistant Enterococcus clinical isolates in Belgium from 2013 to 2021

Journal of Global Antimicrobial Resistance
Objectives: Linezolid-resistant opportunistic human pathogens Enterococcus faecalis and Enterococcus faecium are emerging health threats as limited therapeutic options remain.
Olivier Mortelé, Stefanie van Kleef–van Koeveringe, Sarah Vandamme, Hilde Jansens, Herman Goossens, Veerle Matheeussen   +5 more
doaj   +1 more source