Results 61 to 70 of about 2,219,397 (166)

Clinical outcomes of empirical topical nifuratel or nitrofurantoin in Streptococcus pyogenes vulvovaginitis: A retrospective study

International Journal of Gynecology &Obstetrics, EarlyView.
Marek Stefan, Kristyna Krogh, Jaroslava Zikova, Marta Novackova, Marcela Krutova   +4 more
wiley   +1 more source

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, Volume 53, Issue 11, Page 1042-1050, November 2026.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Clinical guideline highlights for the hospitalist: Updates on the treatment of drug‐susceptible and drug‐resistant tuberculosis

Journal of Hospital Medicine, EarlyView.
Allison Stickles, Anna Poston‐Blahnik, Elizabeth Schlaudecker, Moises Huaman   +3 more
wiley   +1 more source

Beyond the Monolayer: Leveraging 3D Culture Systems to Decode Mechanisms of Drug Resistance and Therapeutic Vulnerabilities in Colorectal Cancer

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Two‐dimensional (2D) monolayer cultures remain the workhorse of colorectal cancer (CRC) research and high‐throughput screening (HTS), yet they poorly recapitulate tissue architecture, extracellular matrix (ECM) cues, metabolic gradients, and multicellular heterogeneity that govern drug response in vivo. Over the past decade, three‐dimensional (
Sarah J. Harmych, Bhuminder Singh
wiley   +1 more source

Synergy of Linezolid with Several Antimicrobial Agents against Linezolid-Methicillin-Resistant Staphylococcal Strains

, 2020
Linezolid is a synthetic oxazolydinone active against multi-resistant Gram-positive cocci that inhibits proteins synthesis by interacting with the 50S ribosomal subunit.
Esther Culebras, María-José Valderrama, María Alfaro, Icíar Rodríguez-Avial, Elvira Baos, Carmen Rodríguez-Avial   +5 more
core   +1 more source

Utility of Metagenomic Next‐Generation Sequencing in Identifying Anaerobic Pathogens in a Pediatric Brain Abscess Secondary to Sinusitis: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In this pediatric brain abscess case, metagenomic next‐generation sequencing (mNGS) identified an anaerobic bacterium that remained undetected using conventional culture methods, thus providing clinically relevant information for antimicrobial management. This indicates that mNGS may be a useful adjunct for optimizing treatment strategies.
Risa Nagase, Kunihiro Oba, Mari Asakura, Masashi Ogasawara, Masahiro Noda, Yusuke Yamada, Asayo Furukawa, Naoki Kojima, Masanori Hashino, Kazuhiro Horiba   +9 more
wiley   +1 more source

Detection of poxtA- and optrA-carrying E. faecium isolates in air samples of a Spanish swine farm

Journal of Global Antimicrobial Resistance, 2020
Objective: Two linezolid-resistant Enterococcus faecium isolates, C10004 and C10009, were recovered from air samples of a Spanish swine farm and comprehensively characterized.
Laura Ruiz-Ripa, Andrea T. Feßler, Dennis Hanke, Susana Sanz, Carmen Olarte, Inga Eichhorn, Stefan Schwarz, Carmen Torres   +7 more
doaj   +1 more source

Genetic Diversity and Epidemiological Overlap of Staphylococcus aureus at the Animal–Food–Environment–Human Interface Within a One Health Framework

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Integrating farm‐to‐fork and clinical surveillance, this study reveals distinct SCCmec distributions alongside shared spa types across human, animal, and food interfaces. The results of genetic diversity and epidemiological overlap underscore the critical need for coordinated One Health surveillance to monitor multi‐sectoral Staphylococcus aureus ...
Pinar Sagiroglu, Dursun Alp Gundog, Candan Gungor, Kursat Koskeroglu, Mustafa Altay Atalay, Adalet Dishan, Yeliz Ucar, Aytac Akcay, Huseyin Burak Disli, Harun Hizlisoy, Mukaddes Barel, Tekin Kececi, Nurhan Ertas Onmaz   +12 more
wiley   +1 more source

Update on linezolid resistance in staphylococci

, 2012
National audienceLinezolid is the only oxazolidinone antibiotic approved for clinical use. It inhibits bacterial protein synthesis by an original mechanism blocking the initiation phase, at a very early stage.
Bourgeois-Nicolaos, N., Desroches, M., Doucet-Populaire, F., Rouard, C.   +3 more
core   +1 more source

Nasopharyngeal Carriage Rate, Risk Factors, and Co‐Resistance Patterns of Methicillin‐Resistant Staphylococcus aureus in Ethiopia: Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This systematic review and meta‐analysis show that nasopharyngeal carriage of methicillin‐resistant Staphylococcus aureus remains an important public health concern in Ethiopia. High resistance to commonly used antibiotics and significant associations with prior hospitalization and antibiotic use highlight the need for strengthened antimicrobial ...
Simachew Getaneh Endalamew, Sofiya Ayalew Kebede, Solomon Keflie Assefa, Adem Tsegaw Zegeye, Belayneh Jejaw Abate, Dejen kahsay Asgedom, Eliyas Addisu Taye, Endalew Minwuye Andargie, Eyob Akalewold Alemu, Halima Ayalew Kebede, Alebachew Tilahun Wassie, Andnet Yirga Assefa, Yihenew Getahun Ambaw, Helen Brhan Alemaw   +13 more
wiley   +1 more source