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Lipid-Laden Macrophages in Pulmonary Diseases [PDF]
CellsPulmonary surfactants play a crucial role in managing lung lipid metabolism, and dysregulation of this process is evident in various lung diseases. Alternations in lipid metabolism lead to pulmonary surfactant damage, resulting in hyperlipidemia in ...
Yin Zhu +3 more
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Lipid-Laden Macrophages and Inflammation in Atherosclerosis and Cancer: An Integrative View [PDF]
Frontiers in Cardiovascular Medicine, 2022 Atherosclerotic arterial plaques and malignant solid tumors contain macrophages, which participate in anaerobic metabolism, acidosis, and inflammatory processes inherent in the development of either disease.
Miriam Lee-Rueckert +3 more
doaj +7 more sources
Lipid laden macrophages and electronic cigarettes in healthy adults [PDF]
EBioMedicine, 2020 Background: An outbreak of E-cigarette or Vaping Product Use-Associated Lung Injury (EVALI) with significant morbidity and mortality was reported in 2019.
Peter G. Shields +10 more
doaj +5 more sources
Etiology of lipid-laden macrophages in the lung [PDF]
International Immunopharmacology, 2023 Uniquely positioned as sentinel cells constantly exposed to the environment, pulmonary macrophages are vital for the maintenance of the lung lining. These cells are responsible for the clearance of xenobiotics, pathogen detection and clearance, and homeostatic functions such as surfactant recycling.
Andrew J. Gow
exaly +4 more sources
Purple perilla extracts allay ER stress in lipid-laden macrophages. [PDF]
PLoS ONE, 2014 There is a growing body of evidence that excess lipids, hypoxic stress and other inflammatory signals can stimulate endoplasmic reticulum (ER) stress in metabolic diseases.
Sin-Hye Park +4 more
doaj +6 more sources
Lipid‐Laden Macrophage Index as a Diagnostic Tool for Pediatric Aspiration: A Systematic Review
OTO Open, 2023 Objective Lipid‐laden macrophage index (LLMI) has been proposed as a marker for aspiration on bronchoalveolar lavage. It has also been studied as a marker for gastroesophageal reflux and other pulmonary diseases.
Claire M. Lawlor, Sukgi S. Choi
doaj +4 more sources
The Unique Phenotype of Lipid-Laden Macrophages. [PDF]
Int J Mol Sci, 2021 Macrophages are key multi-talented cells of the innate immune system and are equipped with receptors involved in damage and pathogen recognition with connected immune response guiding signaling systems. In addition, macrophages have various systems that are involved in the uptake of extracellular and intracellular cargo.
van Eijk M, Aerts JMFG.
europepmc +6 more sources
Lipid Laden Macrophages in Respiratory Disease. [PDF]
J Neurogastroenterol Motil, 2017 Letter to the ...
Sadofsky LR +3 more
europepmc +5 more sources
Extracellular vesicles from ovarian cancer cells induce senescent lipid-laden macrophages to facilitate omental metastasis [PDF]
Journal of NanobiotechnologyBackground Ovarian cancer exhibits striking metastatic tropism for the omentum, where lipid-laden macrophages are key mediators that fuel disease progression.
Guoqing Li +13 more
doaj +2 more sources
Lipid-Laden Macrophages cross the Border to Cancer [PDF]
Immunometabolism, 2020 Abstract Within atherosclerotic plaques, macrophages can take up cholesterol and thereby become lipid-laden cells. For long it has been thought that these foamy macrophages are the main contributors to chronic inflammatory responses in plaques.
Jan Van den Bossche
exaly +2 more sources