Results 31 to 40 of about 1,859,933 (297)

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Thiessen, K., Parhofer, K. G., Fischer, S., Sauter, G. H., Jungst, D., Jungst, C.   +5 more
core   +1 more source

A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER[S]

Journal of Lipid Research, 2010
Dietary lipid absorption is dependent on chylomicron production whose rate-limiting step across the intestinal absorptive cell is the exit of chylomicrons from the endoplasmic reticulum (ER) in its ER-to-Golgi transport vesicle, the prechylomicron ...
Shahzad Siddiqi, Umair Saleem, Nada A. Abumrad, Nicholas O. Davidson, Judith Storch, Shadab A. Siddiqi, Charles M. Mansbach, II   +6 more
doaj   +1 more source

Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice. [PDF]

, 2013
Controlling intestinal lipid absorption is an important strategy for maintaining lipid homeostasis. Accumulation of lipids in the liver is a major risk factor for metabolic syndrome and nonalcoholic fatty liver disease.
Jeffrey S. Cohn (280674), Wong, Gerard, Tandy, S, Weir, Jacquelyn M, Peter J. Meikle (54253), Cohn, Jeffrey S,, Tandy, Sally,, Chung, RWS, Gaire, Raj,, Jacquelyn M. Weir (280671), Rye, Kerry-Anne,, Sally Tandy (280670), Cohn, JS, Sally Tandy, Kamili, Alvin,, Gerard Wong (280673), Meikle, Peter J, Tandy, Sally, Wong, Gerard,, Cohn, Jeffrey S, Kerry-Anne Rye, Alvin Kamili (280669), Gerard Wong, Peter J Meikle, Meikle, PJ, Jacquelyn M Weir, Gaire, Raj, Wong, G, Chung, Rosanna W S,, Chung, Rosanna W S, Kamili, A, Rosanna W S Chung, Kamili, Alvin, Weir, JM, Gaire, R, Alvin Kamili, Jeffrey S Cohn, Meikle, Peter J,, Rye, Kerry-Anne, Rye, KA, Rosanna W. S. Chung (280668), Weir, Jacquelyn M,, Raj Gaire, Raj Gaire (280672), Kerry-Anne Rye (280675), Weir Jacquelyn M., Gaire Raj, Wong Gerard, Kamili Alvin, Rye Kerry-Anne, Cohn Jeffrey S., Tandy Sally, Meikle Peter J., Chung Rosanna W. S.   +53 more
core   +1 more source

The Absorption of Phosphonium Cations and Dications into a Hydrated POPC Phospholipid Bilayer: a Computational Study [PDF]

, 2022
Molecular dynamics (MD) based on an empirical force field is applied to investigate the effect of phosphonium cations ([P 6,6,6,6 ] + ) and geminal dications ([DxC10] 2+ ) inserted at T = 300 K into the hydration layer separating planar POPC phospholipid
Antonio, Benedetto, Pietro, Ballone, Pallavi, Kumari, Visakh, Pillai, Dorothea, Gobbo, Pallavi Kumari, Dorothea Gobbo, Visakh Pillai, Antonio Benedetto, Pietro Ballone   +9 more
core   +2 more sources

Estimation of flattening coefficient for absorption and circular dichroism using simulation [PDF]

, 2009
The absorbance and circular dichroism (CD) of suspensions is lower than if the same amount of chromophore were uniformly distributed throughout the medium. Several mathematical treatments of this absorption flattening phenomenon have been presented using
Halling, Peter J.
core   +4 more sources

Intracellular movement of triacylglycerols in the intestine

Journal of Lipid Research, 1998
The intestine can vary its triacylglycerol output rate depending on differing physiological conditions. The rate-limiting step in the complex process from fatty acid and monoacylglycerol entry to triacylglycerol export is unknown but suggested to be the ...
Charles M. Mansbach, II, Peter Nevin
doaj   +1 more source

A new in vitro lipid digestion - in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations [PDF]

, 2016
Purpose: In vitro lipid digestion models are commonly used to screen lipid-based formulations (LBF), but in vitro-in vivo correlations are in some cases unsuccessful.
Crum, Matthew, Williams, Hywel David, Trevaskis, Natalie, Pouton, Colin William; id_orcid, Porter, Christopher John; id_orcid   +4 more
core   +1 more source

Clock is important for food and circadian regulation of macronutrient absorption in mice

Journal of Lipid Research, 2009
Clock genes respond to external stimuli and exhibit circadian rhythms. This study investigated the expression of clock genes in the small intestine and their contribution in the regulation of nutrient absorption by enterocytes.
Xiaoyue Pan, M. Mahmood Hussain
doaj   +1 more source

Mécanisme d’absorption intestinale des acides gras à longue chaîne : rôle émergent du CD36

Oléagineux, Corps gras, Lipides, 2012
Excessive lipid intake, associated with a qualitative imbalance, favors the development of obesity and associated diseases. From organs involved in the lipid homeostasis, the small intestine remains the most poorly known although it is responsible for ...
Tran Thi Thu Trang, Buttet Marjorie, Traynard Véronique, Besnard Philippe, Poirier Hélène, Niot Isabelle   +5 more
doaj   +1 more source

Sec24C is required for docking the prechylomicron transport vesicle with the Golgi

Journal of Lipid Research, 2010
The rate-limiting step in the transit of dietary fat across the intestinal absorptive cell is its exit from the endoplasmic reticulum (ER) in a specialized ER-to-Golgi transport vesicle, the prechylomicron transport vesicle (PCTV).
Shahzad Siddiqi, Shadab A. Siddiqi, Charles M. Mansbach, II   +2 more
doaj   +1 more source