Circadian regulators of intestinal lipid absorption [PDF]
Journal of Lipid Research, 2015 Among all the metabolites present in the plasma, lipids, mainly triacylglycerol and diacylglycerol, show extensive circadian rhythms. These lipids are transported in the plasma as part of lipoproteins.
M. Mahmood Hussain, Xiaoyue Pan
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Amentoflavone-Enriched Selaginella rossii Warb. Suppresses Body Weight and Hyperglycemia by Inhibiting Intestinal Lipid Absorption in Mice Fed a High-Fat Diet [PDF]
Life, 2022 Many Selaginellaceae species are used as traditional medicines in Asia. This study is the first to investigate the anti-obesity and anti-diabetic effects of Selaginella rossii (SR) in high-fat diet (HFD)–fed C57BL/6J mice.
Hwa Lee +9 more
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B. vulgatus ameliorates high-fat diet-induced obesity through modulating intestinal serotonin synthesis and lipid absorption in mice [PDF]
Gut MicrobesThe consumption of high-fat diets (HFD) and an imbalance in gut microbiome are linked to obesity. However, the intricate connection between them and the underlying mechanisms involved in lipid digestion and absorption remain largely unclear.
Xinxin Wen +10 more
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Fatty acid nitroalkenes regulate intestinal lipid absorption [PDF]
Journal of Lipid ResearchFatty acid nitroalkenes (NO2-FA) are tissue-protective and anti-inflammatory endogenous lipid mediators. A unique electrophilic character promotes reversible reactions with protein thiols, influencing key cellular functions. Given their generation during
Francisco J. Schopfer +6 more
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VEGF‐C is required for intestinal lymphatic vessel maintenance and lipid absorption
EMBO Molecular Medicine, 2015 Vascular endothelial growth factor C (VEGF‐C) binding to its tyrosine kinase receptor VEGFR‐3 drives lymphatic vessel growth during development and in pathological processes.
Harri Nurmi +5 more
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Intestinal lipid absorption and lipoprotein formation [PDF]
Current Opinion in Lipidology, 2014 To summarize the evidence for the presence of two lipid absorption pathways and their regulation.Lipid absorption involves hydrolysis of dietary fat in the lumen of the intestine, followed by the uptake of hydrolyzed products by enterocytes. Lipids are resynthesized in the endoplasmic reticulum and are either secreted with chylomicrons and HDLs or ...
Hussain MM.
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FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption [PDF]
Cell Metabolism, 2021 Anders Thorell +2 more
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Identification of novel inhibitors of dietary lipid absorption using zebrafish.
PLoS ONE, 2010 Pharmacological inhibition of dietary lipid absorption induces favorable changes in serum lipoprotein levels in patients that are at risk for cardiovascular disease and is considered an adjuvant or alternative treatment with HMG-CoA reductase inhibitors (
Justin D Clifton +9 more
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Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity [PDF]
Cell Metabolism, 2021 Ruth Gordillo +2 more
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Mechanical regulation of lipid and sugar absorption by Piezo1 in enterocytes
Acta Pharmaceutica Sinica BObesity is primarily caused by excessive intake as well as absorption of sugar and lipid. Postprandial surge in distention pressure and intestinal motility accelerates the absorption of nutrients. The response of intestinal epithelial cells to mechanical
Tian Tao +10 more
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