Results 11 to 20 of about 139,767 (297)
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores. [PDF]
The PAT family of lipid droplet proteins includes 5 members in mammals: perilipin, adipose differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3-12, and OXPAT.
Bickel, Perry E +2 more
core +3 more sources
Summary: Here, we present a protocol to construct artificial lipid droplets to study the binding affinity of lipid droplet-associated proteins. We provide procedures to construct adiposomes and prepare recombinant lipid droplet-associated proteins.
Zelun Zhi +5 more
doaj +1 more source
Rotavirus-Induced Lipid Droplet Biogenesis Is Critical for Virus Replication
A variety of pathogens, including viruses, bacteria and parasites, target cellular lipid droplets for their replication. Rotaviruses (RVs) infect the villous epithelium of the small intestine and are a major cause of acute gastroenteritis in infants and ...
Jeanette M. Criglar +3 more
doaj +1 more source
Lipid Droplet Biogenesis [PDF]
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo, converting cells to emulsions with LDs constituting the dispersed oil phase in the aqueous cytoplasm. Here we review our current view of LD biogenesis.
Tobias C, Walther +2 more
openaire +2 more sources
Intermittent fasting is one of the most common clinical treatments for the obesity, a main risk factor of the metabolic syndrome which can lead to a variety of diseases.
Hongqiang Li +8 more
doaj +1 more source
Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells [PDF]
Besnoitia besnoiti, an apicomplexan parasite of cattle being considered as emergent in Europe, replicates fast in host endothelial cells during acute infection and is in considerable need for energy, lipids and other building blocks for offspring ...
Silva, Liliana M. R. +8 more
core +2 more sources
The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly.
Lipid droplets are essential cellular organelles for storage of fatty acids and triglycerides. The hepatitis C virus (HCV) translocates several of its proteins onto their surface and uses them for production of infectious progeny.
Gabrielle Vieyres +4 more
doaj +1 more source
LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets. [PDF]
Lipid storage droplet protein 5 (LSDP5) is a lipid droplet-associated protein of the PAT (perilipin, adipophilin, and TIP47) family that is expressed in the liver in a peroxisome proliferator-activated receptor alpha (PPARα)-dependent manner; however ...
Hang Li +9 more
doaj +1 more source
PAT family proteins pervade lipid droplet cores
The PAT family proteins, named after perilipin, adipophilin, and the tail-interacting protein of 47 kDa (TIP47), are implicated in intracellular lipid metabolism. They associate with lipid droplets, but how is completely unclear.
Horst Robenek +2 more
doaj +1 more source
Self-assembly of Tween 80 micelles as nanocargos for oregano and trans-cinnamaldehyde plant-derived compounds [PDF]
The self-assembly of Tween 80 (T80) micelles loaded with plant-based oregano essential oil (OR) and trans-cinnamaldehyde (TCA) was studied. The effect of different factors, including the surfactant to oil ratio, the presence of sodium chloride, thermal ...
Claeys, Myriam +4 more
core +1 more source

