Results 31 to 40 of about 1,416,231 (245)
LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets. [PDF]
PLoS ONE, 2012 Lipid storage droplet protein 5 (LSDP5) is a lipid droplet-associated protein of the PAT (perilipin, adipophilin, and TIP47) family that is expressed in the liver in a peroxisome proliferator-activated receptor alpha (PPARα)-dependent manner; however ...
Hang Li +9 more
doaj +1 more source
PAT family proteins pervade lipid droplet cores
Journal of Lipid Research, 2005 The PAT family proteins, named after perilipin, adipophilin, and the tail-interacting protein of 47 kDa (TIP47), are implicated in intracellular lipid metabolism. They associate with lipid droplets, but how is completely unclear.
Horst Robenek +2 more
doaj +1 more source
Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
doaj +1 more source
The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly.
PLoS Pathogens, 2020 Lipid droplets are essential cellular organelles for storage of fatty acids and triglycerides. The hepatitis C virus (HCV) translocates several of its proteins onto their surface and uses them for production of infectious progeny.
Gabrielle Vieyres +4 more
doaj +1 more source
Functions of Stress-Induced Lipid Droplets in the Nervous System
Frontiers in Cell and Developmental Biology, 2022 Lipid droplets are highly dynamic intracellular organelles that store neutral lipids such as cholesteryl esters and triacylglycerols. They have recently emerged as key stress response components in many different cell types. Lipid droplets in the nervous
Eva Islimye +2 more
doaj +1 more source
Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness. [PDF]
, 2020 Antibody-mediated immune responses rely on antigen recognition by the B cell antigen receptor (BCR) and the proper engagement of its intracellular signal effector proteins.
Becker, S. +10 more
core +2 more sources
Cell, 2009 Lipid droplets (LDs) are universal cellular organelles that specialize in the storage of neutral lipids, such as sterol esters and triacylglycerols (see Essay by Farese and Walther, this issue). As such, they provide the main cellular reservoir for lipids of energy storage and membrane synthesis, and they protect cells from the lipotoxic effects of ...
Krahmer, N. +3 more
openaire +3 more sources
Interfacial Reactions of Ozone with Surfactant Protein B in a Model Lung Surfactant System [PDF]
, 2010 Oxidative stresses from irritants such as hydrogen peroxide and ozone (O_3) can cause dysfunction of the pulmonary surfactant (PS) layer in the human lung, resulting in chronic diseases of the respiratory tract.
Beauchamp, J. L. +9 more
core +2 more sources
bioRxiv, 2019 Microglia become progressively activated and seemingly dysfunctional with age, and genetic studies have linked these cells to the pathogenesis of a growing number of neurodegenerative diseases.
J. Marschallinger +17 more
semanticscholar +1 more source
A Novel Photosensitizer for Lipid Droplet–Location Photodynamic Therapy
Frontiers in Chemistry, 2021 Lipid droplets (LDs), an extremely important cellular organelle, are responsible for the storage of neutral lipids in multiple biological processes, which could be a potential target site for photodynamic therapy (PDT) of cancer.
Xiang Xia +9 more
doaj +1 more source