Results 71 to 80 of about 1,416,231 (245)
Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]
, 2016 Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P. +10 more
core +1 more source
Expanding roles for lipid droplets [PDF]
Trends in Endocrinology & Metabolism, 2011 This work was supported by grants from the American Diabetes Association, NIH RO1-DK-082574, and the U.S. Department of Agriculture, Agricultural Research Service, under agreement No. 58-1950-7-70 to ASG. This work was also supported by grants from the NIH RO1-DK59935 and RO1 DK56598 to RAC.
Andrew S, Greenberg, Rosalind A, Coleman
openaire +2 more sources
Lipid droplets promote efficient mitophagy
Autophagy, 2022 Mitophagy neutralizes defective mitochondria via lysosomal elimination. Increased levels of mitophagy hallmark metabolic transitions and are induced by iron depletion, yet its metabolic basis has not been studied in-depth. How mitophagy integrates with different homeostatic mechanisms to support metabolic integrity is incompletely understood.
Maeve Long, Thomas G. McWilliams
openaire +3 more sources
The Vacuole Lipid Droplet Contact Site vCLIP
ContactLipid droplets frequently form contact sites with the membrane of the vacuole, the lysosome-like organelle in yeast. These vacuole lipid droplet (vCLIP) contact sites respond strongly to metabolic cues: while only a subset of lipid droplets is bound to ...
Duy Trong Vien Diep, Maria Bohnert
doaj +1 more source
STAR Protocols, 2021 Summary: Lipid droplets are endoplasmic reticulum-derived neutral lipid storage organelles that play critical roles in cellular lipid and energy homeostasis. Here, we present a protocol for the identification of high-confidence lipid droplet proteomes in
Clark W.H. Peterson +3 more
doaj +1 more source
Dissection of surface area-dependent lipolysis at a single organelle level
Cell ReportsSummary: Lipid droplets are dynamic organelles whose size and number signify their role in energy. However, owing to cellular heterogeneity and technological limitations, the relationship between the lipolytic ability and lipid droplet morphology is ...
Chengxin Ma +9 more
doaj +1 more source
Single-cell profiling reveals the origin of phenotypic variability in adipogenesis.
PLoS ONE, 2009 Phenotypic heterogeneity in a clonal cell population is a well-observed but poorly understood phenomenon. Here, a single-cell approach is employed to investigate non-mutative causes of phenotypic heterogeneity during the differentiation of 3T3-L1 cells ...
Thuc T Le, Ji-Xin Cheng
doaj +1 more source
Advanced ScienceSpinal cord injury is characterized by high incidence and high disability, and the specific targets and drugs have not yet been explored. Lipid droplet is a type of organelles that regulates lipid metabolism and oxidative stress.
Lu Chen +6 more
doaj +1 more source
Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases
Cell & Bioscience, 2022 The importance of neuroglia in maintaining normal brain function under physiological and pathological conditions has been supported by growing evidence in recent years.
Danying Yang +9 more
doaj +1 more source
Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors
, 2008 Intracellular transport is based on molecular motors that pull cargos along cytoskeletal filaments. One motor species always moves in one direction, e.g.
Klumpp, Stefan +2 more
core +2 more sources