Results 11 to 20 of about 1,446,619 (399)
Lipid Droplets in Cancer. [PDF]
Reviews of Physiology, Biochemistry and Pharmacology, 2020 Lipid droplets have a unique structure among organelles consisting of a dense hydrophobic core of neutral lipids surrounded by a single layer of phospholipids decorated with various proteins. Often labeled merely as passive fat storage repositories, they
T. Petan
semanticscholar +3 more sources
Lipid Droplets in Disease [PDF]
Cells, 2019 Lipid droplets (LDs) are a crucial part of lipid storage; thus, they are important players in a variety of diseases that are affected by lipid imbalances such as obesity, fatty liver disease, type 2 diabetes, Alzheimer’s disease, cardiovascular ...
Paul Dalhaimer
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Lipid Droplets in Neurodegenerative Disorders [PDF]
Frontiers in Neuroscience, 2020 Knowledge of lipid droplets (LDs) has evolved from simple depots of lipid storage to dynamic and functionally active organelles involved in a variety of cellular functions.
Brandon C Farmer +3 more
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Trends in Cell Biology, 2021 All living organisms can make lipid droplets (LDs), intracellular oil-in-water droplets, surrounded by a phospholipid and protein monolayer. LDs are at the nexus of cellular lipid metabolism and function in diverse biological processes. During the past decade, multidisciplinary approaches have shed light on LD assembly steps from the endoplasmic ...
Thiam, Abdou Rachid, Ikonen, Elina
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Lipid droplet biogenesis [PDF]
Current Opinion in Cell Biology, 2014 Lipid droplets (LDs) are found in most cells, where they play central roles in energy and membrane lipid metabolism. The de novo biogenesis of LDs is a fascinating, yet poorly understood process involving the formation of a monolayer bound organelle from a bilayer membrane.
Florian, Wilfling +3 more
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Lipid droplet metabolism [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2013 With the realization that lipid droplets are not merely inert fat storage organelles, but highly dynamic and actively involved in cellular lipid homeostasis, there has been an increased interest in lipid droplet biology. Recent studies have begun to unravel the roles that lipid dropletss play in cellular physiology and provide insights into the ...
Victor K, Khor +2 more
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Interplay between lipid droplets and alpha-synuclein: implication in Parkinson's disease pathogenesis. [PDF]
Front Mol NeurosciIdi W, Sheta R, Oueslati A.
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The ménage à trois of autophagy, lipid droplets and liver disease
Autophagy, 2021 Autophagic pathways cross with lipid homeostasis and thus provide energy and essential building blocks that are indispensable for liver functions. Energy deficiencies are compensated by breaking down lipid droplets (LDs), intracellular organelles that ...
Yasmina Filali-Mouncef +7 more
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Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance Lipid droplets (LDs) are ubiquitous organelles that play important roles in cellular energy homeostasis, tightly regulating the accumulation and release of lipids. In macrophages, lipids accumulate in LDs during inflammation.
Xanthe A M H van Dierendonck +10 more
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The Plant Cell, 2022 Abstract Membrane contact sites (MCSs) are interorganellar connections that allow for the direct exchange of molecules, such as lipids or Ca2+ between organelles, but can also serve to tether organelles at specific locations within cells.
Hannah Elisa Krawczyk +14 more
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