Results 11 to 20 of about 98,017 (217)

Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes.

Journal of Lipid Research, 1995
Immunocytochemistry was used to determine the intracellular location of perilipins in adipocytes and the occurrence of these proteins in tissues involved in triacylglycerol metabolism.
E.J. Blanchette-Mackie, N.K. Dwyer, T. Barber, R.A. Coxey, T. Takeda, C.M. Rondinone, J.L. Theodorakis, A.S. Greenberg, C. Londos   +8 more
doaj   +1 more source

Microsomal Triglyceride Transfer Protein (MTP) Associates with Cytosolic Lipid Droplets in 3T3-L1 Adipocytes. [PDF]

PLoS ONE, 2015
Lipid droplets are intracellular energy storage organelles composed of a hydrophobic core of neutral lipid, surrounded by a monolayer of phospholipid and a diverse array of proteins.
Joseph D Love, Takashi Suzuki, Delia B Robinson, Carla M Harris, Joyce E Johnson, Peter J Mohler, W Gray Jerome, Larry L Swift   +7 more
doaj   +1 more source

Surface-associated lipid droplets: an intermediate site for lipid transport in human adipocytes?

Adipocyte, 2020
Adipose tissue plays a major role in regulating whole-body energy metabolism. While the biochemical processes regulating storage and release of excess energy are well known, the temporal organization of these events is much less defined.
Björn Morén, Claes Fryklund, Karin Stenkula   +2 more
doaj   +1 more source

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects[S]

Journal of Lipid Research, 2010
Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin, Soazig Le Lay, Anita Eberl, Harald C. Köfeler, Ida Chiara Guerrera, Christophe Klein, Xavier Le Liepvre, Françoise Lasnier, Olivier Bourron, Jean-François Gautier, Pascal Ferré, Eric Hajduch, Isabelle Dugail   +12 more
doaj   +1 more source

Role of endogenous lipid droplets in lipolysis in rat adipocytes.

Journal of Lipid Research, 1994
Sonication of rat fat cells caused an increase in lipolysis in the absence of lipolytic stimulants (basal lipolysis) and loss of epinephrine responsiveness.
H Okuda, C Morimoto, T Tsujita
doaj   +1 more source

15(S)-Lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: evidence of lipid droplet metabolism

Journal of Lipid Research, 2009
15(S)-lipoxygenase-1 (15-LO-1) was present in the whole-cell homogenate of an acute human monocytic leukemia cell line (THP-1). Additionally, 15-LO-1 was detected on neutral lipid droplets isolated from THP-1 foam cells.
Ginny L. Weibel, Michelle R. Joshi, Cong Wei, Sandra R. Bates, Ian A. Blair, George H. Rothblat   +5 more
doaj   +1 more source

Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein

Journal of Lipid Research, 1997
The adipose differentiation-related protein (ADRP) was first characterized as a mRNA induced early during adipocyte differentiation (Jiang, H. P., and G. Serrero. 1992. Proc. Natl. Acad. Sci. USA. 89:7856-7860).
D L Brasaemle, T Barber, N E Wolins, G Serrero, E J Blanchette-Mackie, C Londos   +5 more
doaj   +1 more source

An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish

eLife, 2021
Lipid droplets are lipid storage organelles found in nearly all cell types from adipocytes to cancer cells. Although increasingly implicated in disease, current methods to study lipid droplets in vertebrate models rely on static imaging or the use of ...
Dianne Lumaquin, Eleanor Johns, Emily Montal, Joshua M Weiss, David Ola, Abderhman Abuhashem, Richard M White   +6 more
doaj   +1 more source

Lipid droplets as ubiquitous fat storage organelles in C. elegans

BMC Cell Biology, 2010
Background Lipid droplets are a class of eukaryotic cell organelles for storage of neutral fat such as triacylglycerol (TAG) and cholesterol ester (CE).
Guo Fengli, Trimble Rhonda, Zhang Shaobing O, Mak Ho   +3 more
doaj   +1 more source

Label-free third harmonic generation imaging and quantification of lipid droplets in live filamentous fungi

Scientific Reports, 2022
We report the utilization of Third-Harmonic Generation microscopy for label-free live cell imaging of lipid droplets in the hypha of filamentous fungus Phycomyces blakesleeanus.
Tanja Pajić, Nataša V. Todorović, Miroslav Živić, Stanko N. Nikolić, Mihailo D. Rabasović, Andrew H. A. Clayton, Aleksandar J. Krmpot   +6 more
doaj   +1 more source