Results 21 to 30 of about 174,447 (304)
Lipid coated liquid crystal droplets for the on-chip detection of antimicrobial peptides [PDF]
, 2019 We describe a novel biosensor based on phospholipid-coated nematic liquid crystal (LC) droplets and demonstrate the detection of Smp43, a model antimicrobial peptide (AMP) from the venom of North African scorpion Scorpio maurus palmatus.
Bao, Peng +9 more
core +1 more source
Cell, 2009 Lipid droplets (LDs) are universal cellular organelles that specialize in the storage of neutral lipids, such as sterol esters and triacylglycerols (see Essay by Farese and Walther, this issue). As such, they provide the main cellular reservoir for lipids of energy storage and membrane synthesis, and they protect cells from the lipotoxic effects of ...
Krahmer, N. +3 more
openaire +3 more sources
Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes.
Journal of Lipid Research, 1995 Immunocytochemistry was used to determine the intracellular location of perilipins in adipocytes and the occurrence of these proteins in tissues involved in triacylglycerol metabolism.
E.J. Blanchette-Mackie +8 more
doaj +1 more source
Microsomal Triglyceride Transfer Protein (MTP) Associates with Cytosolic Lipid Droplets in 3T3-L1 Adipocytes. [PDF]
PLoS ONE, 2015 Lipid droplets are intracellular energy storage organelles composed of a hydrophobic core of neutral lipid, surrounded by a monolayer of phospholipid and a diverse array of proteins.
Joseph D Love +7 more
doaj +1 more source
Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy. [PDF]
, 2008 The original publication is available at www.springerlink.comInternational audienceThe mechanisms underlying hepatitis C virus (HCV) morphogenesis remain elusive, but lipid droplets have recently been shown to be important organelles for virus production.
Blanchard, Emmanuelle +3 more
core +3 more sources
Lipid droplets and lipotoxicity during autophagy. [PDF]
, 2017 Lipid droplets (LDs) are neutral lipid storage organelles that provide a rapidly accessible source of fatty acids (FAs) for energy during periods of nutrient deprivation.
Nguyen, Truc, Olzmann, James
core +2 more sources
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]
, 2010 Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud +7 more
core +1 more source
Surface-associated lipid droplets: an intermediate site for lipid transport in human adipocytes?
Adipocyte, 2020 Adipose tissue plays a major role in regulating whole-body energy metabolism. While the biochemical processes regulating storage and release of excess energy are well known, the temporal organization of these events is much less defined.
Björn Morén +2 more
doaj +1 more source
Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
doaj +1 more source
Lipid droplets in stress protection: distinct mechanisms of lipid droplet microautophagy
Autophagy Reports, 2022 Lipid droplets (LDs) are organelles that function as sites for lipid storage. LDs have also been implicated in the cellular response to proteotoxic or lipotoxic stress as sites for sequestering dysfunctional or excess proteins or lipids, and targeting those cargos for degradation by LD microautophagy (microlipophagy, μLP).
Pin-Chao Liao, Liza A. Pon
openaire +3 more sources