Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
doaj +1 more source
Surface-associated lipid droplets: an intermediate site for lipid transport in human adipocytes?
Adipocyte, 2020 Adipose tissue plays a major role in regulating whole-body energy metabolism. While the biochemical processes regulating storage and release of excess energy are well known, the temporal organization of these events is much less defined.
Björn Morén +2 more
doaj +1 more source
Some Like It Fat: Comparative Ultrastructure of the Embryo in Two Demosponges of the Genus Mycale (Order Poecilosclerida) from Antarctica and the Caribbean [PDF]
, 2015 0000-0002-7993-1523© 2015 Riesgo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License [4.0], which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
A Clarke +83 more
core +2 more sources
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]
, 2010 Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud +7 more
core +1 more source
Lipid droplets in stress protection: distinct mechanisms of lipid droplet microautophagy
Autophagy Reports, 2022 Lipid droplets (LDs) are organelles that function as sites for lipid storage. LDs have also been implicated in the cellular response to proteotoxic or lipotoxic stress as sites for sequestering dysfunctional or excess proteins or lipids, and targeting those cargos for degradation by LD microautophagy (microlipophagy, μLP).
Pin-Chao Liao, Liza A. Pon
openaire +3 more sources
Role of endogenous lipid droplets in lipolysis in rat adipocytes.
Journal of Lipid Research, 1994 Sonication of rat fat cells caused an increase in lipolysis in the absence of lipolytic stimulants (basal lipolysis) and loss of epinephrine responsiveness.
H Okuda, C Morimoto, T Tsujita
doaj +1 more source
Morphological features of lipid droplet transition during porcine oocyte fertilisation and early embryonic development to blastocyst in vivo and in vitro [PDF]
, 2002 Lipid content in mammalian oocytes or embryos differs among species, with bovine and porcine oocytes and embryos showing large cytoplasmic droplets.
Ekwall, Hans +6 more
core +1 more source
Lipid droplets go nuclear [PDF]
Journal of Cell Biology, 2016 Lipid droplets (LDs) are sometimes found in the nucleus of some cells. In this issue, Ohsaki et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507122) show that the nuclear membrane, promyelocytic leukemia bodies, and the protein PML-II play a role in nuclear LD formation, suggesting functional relationships between these structures.
Farese, Robert, Walther, Tobias
openaire +3 more sources
Journal of Lipid Research, 1997 The adipose differentiation-related protein (ADRP) was first characterized as a mRNA induced early during adipocyte differentiation (Jiang, H. P., and G. Serrero. 1992. Proc. Natl. Acad. Sci. USA. 89:7856-7860).
D L Brasaemle +5 more
doaj +1 more source
Lipid droplet detection by the cavity perturbation method [PDF]
, 2011 There are currently no point-of-care diagnosis strategies available to indicate the presence of neoplasmic growth. This research aims to develop a novel diagnostic strategy based on detecting TAG accumulation in cells.
A I Al-Shamma'a +7 more
core +1 more source