Results 1 to 10 of about 333,781 (210)

Nitro-fatty acids: novel anti-inflammatory lipid mediators [PDF]

Brazilian Journal of Medical and Biological Research, 2013
Nitro-fatty acids are formed and detected in human plasma, cell membranes, and tissue, modulating metabolic as well as inflammatory signaling pathways.
H. Rubbo
doaj   +2 more sources

Docosahexaenoic Acid Increases the Pro-Resolving Brain Lipid Mediators of Inflammation in Rat Pups Prenatally Exposed to Alcohol [PDF]

Life
Fetal alcohol spectrum disorder (FASD/FAS) is a chronic inflammatory process of the fetal brain induced by alcohol and mediated by pro-inflammatory (PILM) and pro-resolving (PRLM) lipid mediators of inflammation.
Enrique M. Ostrea, Deepak Yadav, Charlie T. Cheng, Esther D. Kisseih, Krishna R. Maddipati, Ronald L. Thomas   +5 more
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Roles of lipid mediators in early pregnancy events [PDF]

Reproductive Medicine and Biology
Background Early pregnancy events, including embryo implantation, are critical for maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling pathways implicated in establishing early pregnancy, a comprehensive understanding ...
Shizu Aikawa, Yasushi Hirota
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Differential effect of an evolving amyloid and tau pathology on brain phospholipids and bioactive lipid mediators in rat models of Alzheimer-like pathology [PDF]

Journal of Neuroinflammation
Background Brain inflammation contributes significantly to the pathophysiology of Alzheimer’s disease, and it is manifested by glial cell activation, increased production of cytokines/chemokines, and a shift in lipid mediators from a pro-homeostatic to a
Sonia Do Carmo, Marie-Audrey I. Kautzmann, Surjyadipta Bhattacharjee, Bokkyoo Jun, Carolyn Steinberg, Joshua T. Emmerson, Janice C. Malcolm, Quentin Bonomo, Nicolas G. Bazan, A. Claudio Cuello   +9 more
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Subgingival Microbiome and Specialized Pro-Resolving Lipid Mediator Pathway Profiles Are Correlated in Periodontal Inflammation

Frontiers in Immunology, 2021
Failure of resolution pathways in periodontitis is reflected in levels of specialized pro-resolving lipid mediators (SPMs) and SPM pathway markers but their relationship with the subgingival microbiome is unclear.
Chun-Teh Lee, Ruoxing Li, Lisha Zhu, Gena D. Tribble, W. Jim Zheng, Brittney Ferguson, Krishna Rao Maddipati, Nikola Angelov, Thomas E. Van Dyke, Thomas E. Van Dyke   +9 more
doaj   +1 more source

Linoleate-Rich Safflower Oil Diet Increases Linoleate-Derived Bioactive Lipid Mediators in Plasma, and Brown and White Adipose Depots of Healthy Mice

Metabolites, 2022
Polyunsaturated fats are energy substrates and precursors to the biosynthesis of lipid mediators of cellular processes. Adipose tissue not only provides energy storage, but influences whole-body energy metabolism through endocrine functions.
Deena B. Snoke, Austin Angelotti, Kamil Borkowski, Rachel M. Cole, John W. Newman, Martha A. Belury   +5 more
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Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin interventionResearch in context

EBioMedicine, 2023
Summary: Background: Persons with HIV (PWH) have an increased risk of cardiovascular disease (CVD) compared to HIV-seronegative individuals (SN). Inflammation contributes to this risk but the role of lipid mediators, with central roles in inflammation ...
Jesmond Dalli, Douglas Kitch, Meagan P. O'Brien, Peter W. Hunt, Nicholas Funderburg, Daniela Moisi, Amita Gupta, Todd T. Brown, Phyllis C. Tien, Judith A. Aberg, Rupak Shivakoti   +10 more
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Current knowledge of the implication of lipid mediators in psoriasis

Frontiers in Immunology, 2022
The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions of the skin is its barrier function, mediated notably by the lipids of the stratum corneum, and
Mélissa Simard, Mélissa Simard, Sophie Morin, Sophie Morin, Zainab Ridha, Roxane Pouliot, Roxane Pouliot   +6 more
doaj   +1 more source

The roles of lipid mediators in type I hypersensitivity

Journal of Pharmacological Sciences, 2021
Type I hypersensitivity is an immediate immune reaction that involves IgE-mediated activation of mast cells. Activated mast cells release chemical mediators, such as histamine and lipid mediators, which cause allergic reactions.
Tatsuro Nakamura
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LimeMap: a comprehensive map of lipid mediator metabolic pathways

npj Systems Biology and Applications, 2021
Lipid mediators are major factors in multiple biological functions and are strongly associated with disease. Recent lipidomics approaches have made it possible to analyze multiple metabolites and the associations of individual lipid mediators.
Akinori Nishi, Katsuya Ohbuchi, Noriko Kaifuchi, Chika Shimobori, Hirotaka Kushida, Masahiro Yamamoto, Yoshihiro Kita, Suzumi M. Tokuoka, Ayako Yachie, Yukiko Matsuoka, Hiroaki Kitano   +10 more
doaj   +1 more source