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Lipid Mediators in Acne [PDF]

Mediators of Inflammation, 2010
Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones. The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm the presence of ...
Monica Ottaviani, Emanuela Camera, Mauro Picardo   +2 more
doaj   +3 more sources

Lipid Mediators in Inflammation [PDF]

Microbiology Spectrum, 2016
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core   +5 more sources

Docosahexaenoic Acid Increases the Pro-Resolving Brain Lipid Mediators of Inflammation in Rat Pups Prenatally Exposed to Alcohol [PDF]

Life
Fetal alcohol spectrum disorder (FASD/FAS) is a chronic inflammatory process of the fetal brain induced by alcohol and mediated by pro-inflammatory (PILM) and pro-resolving (PRLM) lipid mediators of inflammation.
Enrique M. Ostrea, Deepak Yadav, Charlie T. Cheng, Esther D. Kisseih, Krishna R. Maddipati, Ronald L. Thomas   +5 more
doaj   +2 more sources

Lipid mediators in diabetic nephropathy [PDF]

Fibrogenesis & Tissue Repair, 2014
The implications of lipid lowering drugs in the treatment of diabetic nephropathy have been considered. At the same time, the clinical efficacy of lipid lowering drugs has resulted in improvement in the cardiovascular functions of chronic kidney disease (
Daisuke Koya, Keizo Kanasaki, Sen Shi, Swayam Srivastava   +3 more
core   +4 more sources

Roles of lipid mediators in early pregnancy events [PDF]

Reproductive Medicine and Biology
Background Early pregnancy events, including embryo implantation, are critical for maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling pathways implicated in establishing early pregnancy, a comprehensive understanding ...
Shizu Aikawa, Yasushi Hirota
doaj   +2 more sources

Differential effect of an evolving amyloid and tau pathology on brain phospholipids and bioactive lipid mediators in rat models of Alzheimer-like pathology [PDF]

Journal of Neuroinflammation
Background Brain inflammation contributes significantly to the pathophysiology of Alzheimer’s disease, and it is manifested by glial cell activation, increased production of cytokines/chemokines, and a shift in lipid mediators from a pro-homeostatic to a
Sonia Do Carmo, Marie-Audrey I. Kautzmann, Surjyadipta Bhattacharjee, Bokkyoo Jun, Carolyn Steinberg, Joshua T. Emmerson, Janice C. Malcolm, Quentin Bonomo, Nicolas G. Bazan, A. Claudio Cuello   +9 more
doaj   +2 more sources

Subgingival Microbiome and Specialized Pro-Resolving Lipid Mediator Pathway Profiles Are Correlated in Periodontal Inflammation

Frontiers in Immunology, 2021
Failure of resolution pathways in periodontitis is reflected in levels of specialized pro-resolving lipid mediators (SPMs) and SPM pathway markers but their relationship with the subgingival microbiome is unclear.
Chun-Teh Lee, Ruoxing Li, Lisha Zhu, Gena D. Tribble, W. Jim Zheng, Brittney Ferguson, Krishna Rao Maddipati, Nikola Angelov, Thomas E. Van Dyke, Thomas E. Van Dyke   +9 more
doaj   +1 more source

Linoleate-Rich Safflower Oil Diet Increases Linoleate-Derived Bioactive Lipid Mediators in Plasma, and Brown and White Adipose Depots of Healthy Mice

Metabolites, 2022
Polyunsaturated fats are energy substrates and precursors to the biosynthesis of lipid mediators of cellular processes. Adipose tissue not only provides energy storage, but influences whole-body energy metabolism through endocrine functions.
Deena B. Snoke, Austin Angelotti, Kamil Borkowski, Rachel M. Cole, John W. Newman, Martha A. Belury   +5 more
doaj   +1 more source

Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin interventionResearch in context

EBioMedicine, 2023
Summary: Background: Persons with HIV (PWH) have an increased risk of cardiovascular disease (CVD) compared to HIV-seronegative individuals (SN). Inflammation contributes to this risk but the role of lipid mediators, with central roles in inflammation ...
Jesmond Dalli, Douglas Kitch, Meagan P. O'Brien, Peter W. Hunt, Nicholas Funderburg, Daniela Moisi, Amita Gupta, Todd T. Brown, Phyllis C. Tien, Judith A. Aberg, Rupak Shivakoti   +10 more
doaj   +1 more source

Lipid-Mediated Endocytosis [PDF]

Cold Spring Harbor Perspectives in Biology, 2011
Receptor-mediated endocytosis is used by a number of viruses and toxins to gain entry into cells. Some have evolved to use specific lipids in the plasma membrane as their receptors. They include bacterial toxins such as Shiga and Cholera toxin and viruses such as mouse polyoma virus and simian virus 40. Through multivalent binding to glycosphingolipids,
Ewers, Helge, Helenius, Ari
openaire   +3 more sources