Results 31 to 40 of about 333,930 (355)

Eosinophil Recruitment and Activation: The Role of Lipid Mediators

open access: yesFrontiers in Pharmacology, 2013
Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving eosinophil selective accumulation in sites of allergic inflammation are well established and ...
Tatiana eLuna-Gomes   +2 more
doaj   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201

open access: yesJournal of Inflammation Research, 2022
Christian Kretzer,1 Paul M Jordan,1 Rossella Bilancia,2 Antonietta Rossi,2 Tuğçe Gür Maz,3 Erden Banoglu,3 Ulrich S Schubert,4,5 Oliver Werz1,5 1Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University
Kretzer C   +7 more
doaj  

Macrophage autophagy in atherosclerosis [PDF]

open access: yes, 2013
Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R.   +5 more
core   +2 more sources

Host Lipid Mediators in Leprosy: The Hypothesized Contributions to Pathogenesis

open access: yesFrontiers in Immunology, 2018
The spectrum of clinical forms observed in leprosy and its pathogenesis are dictated by the host’s immune response against Mycobacterium leprae, the etiological agent of leprosy.
Carlos A. M. Silva, John T. Belisle
doaj   +1 more source

Ratio of pro-resolving and pro-inflammatory lipid mediator precursors as potential markers for aggressive periodontitis. [PDF]

open access: yesPLoS ONE, 2013
Aggressive periodontitis (AgP) is a rapidly progressing type of periodontal disease in otherwise healthy individuals which causes destruction of the supporting tissues of the teeth.
Hager R Zein Elabdeen   +5 more
doaj   +1 more source

Ultrafine particles affect the balance of endogenous pro- and anti-inflammatory lipid mediators in the lung: in-vitro and in-vivo studies

open access: yesParticle and Fibre Toxicology, 2012
Background Exposure to ultrafine particles exerts diverse harmful effects including aggravation of pulmonary diseases like asthma. Recently we demonstrated in a mouse model for allergic airway inflammation that particle-derived oxidative stress plays a ...
Beck-Speier Ingrid   +4 more
doaj   +1 more source

Associations between Plasma Lipid Mediators and Chronic Daily Headache Outcomes in Patients Randomized to a Low Linoleic Acid Diet with or without Added Omega-3 Fatty Acids

open access: yesMetabolites, 2023
A previous report showed that 12-week lowering of dietary omega-6 linoleic acid (LA) coupled with increased omega-3 polyunsaturated fatty acid (PUFA) intake (H3-L6 diet) reduced headache frequency and improved quality of life in patients with chronic ...
Qing Shen   +9 more
doaj   +1 more source

Proresolving lipid mediators enhance PMN-mediated bacterial clearance [PDF]

open access: yesProceedings of the National Academy of Sciences, 2020
Host responses to bacterial infection are protective, yet without timely resolution they can lead to uncontrolled infection, with systemic engagement and multiple organ failure. In PNAS, Sekheri et al. (1) report the property of specific lipid mediators to counteract the delay tactics of bacterial DNA released from proliferating or dying bacteria as ...
Lucy V. Norling, Mauro Perretti
openaire   +2 more sources

Eicosapentaenoic Acid Influences the Lipid Profile of an In Vitro Psoriatic Skin Model Produced with T Cells

open access: yesBiomolecules, 2023
Psoriasis is a skin disease characterized by epidermal hyperplasia and an inappropriate activation of the adaptive immunity. A dysregulation of the skin’s lipid mediators is reported in the disease with a predominance of the inflammatory cascade derived ...
Sophie Morin   +5 more
doaj   +1 more source

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