Results 21 to 30 of about 87,561 (363)

Ferroptosis: Mechanism and connections with cutaneous diseases

Frontiers in Cell and Developmental Biology, 2023
Ferroptosis is a recognized novel form of programmed cell death pathway, featuring abnormalities in iron metabolism, SystemXc−/glutathione axis, and lipid peroxidation regulation.
Lihao Liu, Ni Lian, Liqing Shi, Zhimin Hao, Kun Chen   +4 more
doaj   +1 more source

The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

Cell Reports, 2021
Summary: T regulatory (Treg) cells are crucial to maintain immune tolerance and repress antitumor immunity, but the mechanisms governing their cellular redox homeostasis remain elusive.
Chengxian Xu, Shaogang Sun, Travis Johnson, Rong Qi, Siyuan Zhang, Jie Zhang, Kai Yang   +6 more
doaj   +1 more source

Lipid Peroxidation

, 2021
Lipid peroxidation (LPO) is initiated by the attack of free radicals (eg OH ·, O2- and H2O2) on cellular or organelle membranes phospholipids or polyunsaturated fatty acids (PUFA), and with the formation of various types of aldehydes, ketones, alkanes, carboxylic acids and polymerization products. It is an autoxidation process that results.
Onur, Yaman, Suzan, Adnan, Ayhanci,
openaire   +3 more sources

A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent.

Journal of Lipid Research, 1989
A method is described for measuring lipid peroxides by means of the color reagent of a commercially available test kit for cholesterol estimation. In principle, this assay makes use of the oxidative capacity of lipid peroxides to convert iodide to iodine,
M el-Saadani, H Esterbauer, M el-Sayed, M Goher, A Y Nassar, G Jürgens   +5 more
doaj   +1 more source

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review

Frontiers in Physiology, 2019
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD) characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and biochemically different from known types of cell death. Ferroptosis plays a vital
Pengxu Lei, Tao Bai, Yuling Sun
doaj   +1 more source

The single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene influences endothelial cell function : Interaction with selenium and fatty acids [PDF]

, 2013
© 2013 The Authors. Molecular Nutrition & Food Research published by Wiley-VCH Verlag GmbH & Co.
Akbaraly, Bellinger, Bermano, Bermano, Björnstedt, Brigelius-Flohé, Brigelius-Flohé, Drummen, Gautrey, Gong, Gu, Hayden, Hesketh, Kretz-Remy, Libby, Lubos, Mata, Mayer, Miller, Mozaffarian, Méplan, Phillips, Polonikov, Rayman, Sneddon, Sneddon, Sneddon, Sutherland, Thies, To, Udler, Villette   +31 more
core   +8 more sources

Oral supplementation with organically modified clinoptilolite during prepartum period influences the redox status of peripheral blood and colostrum of primiparous dairy cows

Italian Journal of Animal Science, 2022
Redox imbalance in peripartum period influences health of dairy cows and their foetus and, through the colostrum, health of new-born calves. Oxidative stress in cattle can be suppressed by dietary supplementation with natural minerals, and we ...
Ivana Drvenica, Milica Stojić, Natalija Fratrić, Marijana Kovačić, Jelica Grujić-Milanović, Branislav Vejnović, Dragana Marković, Dragan Gvozdić, Vesna Ilić   +8 more
doaj   +1 more source

A Modified d-ROMs Method for Determination of Lipid Peroxidation [PDF]

Journal of Stress Physiology & Biochemistry, 2022
The need for simple and low costing and less time consuming methods for the determination of lipid peroxides and oxidative stress is urgent because oxidative stress is still unable to become a routine laboratory biomarker due to the sophisticated ...
Muammar A Y Nassar, Saleh H Sharif, Khalda M A Hammad   +2 more
doaj  

Ferroptosis-associated gene SLC7A11 is upregulated in NSCLC and correlated with patient’s poor prognosis: An integrated bioinformatics analysis

Pteridines, 2021
Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, which was involved in the progression of malignant tumors including non-small cell lung cancer (NSCLC).
Huang He, Liu Juan, Wu Haiyan, Liu Fang, Zhou Xiaoxi   +4 more
doaj   +1 more source

Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]

, 2016
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo, Palmery, Maura, Peluso, Ilaria   +2 more
core   +2 more sources