Results 11 to 20 of about 1,963,371 (292)

Hypoxia and lipid signaling [PDF]

open access: yesBiological Chemistry, 2006
Sufficient oxygen supply is crucial for the development and physiology of mammalian cells and tissues. When simple diffusion of oxygen becomes inadequate to provide the necessary flow of substrate, evolution has provided cells with tools to detect and ...
Josef Pfeilschifter   +3 more
core   +4 more sources

Lipid signaling in plants

open access: yes, 2010
This book highlights the current status of plant lipid signaling. Written by leading researchers in the field, the chapters include detailed information on the measurement, regulation and function of phospholipases, lipid kinases, lipid phosphatases ...
Munnik, T.
core   +4 more sources

Lipid rafts and insulin signaling

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 2002
Lipid rafts are domains within the plasma membrane that are enriched in cholesterol and lipids with saturated acyl chains. Specific proteins, including many signaling proteins, segregate into lipid rafts, and this process is important for certain signal ...
Perry E. Bickel
core   +3 more sources

A proteomic analysis of lipid raft and GPI anchored proteins in Caenorhabditis elegans [PDF]

open access: yes, 2010
Glycosylphosphatidylinositol (GPI) anchored proteins are a unique group of membrane proteins found on the surface and certain intracellular compartments of eukaryotic cells.
Rao, Wei
core   +6 more sources

Functional characterisation of the lipid raft protein stomatin [PDF]

open access: yes, 2005
The function of the integral membrane protein stomatin is as yet poorly understood. Stomatin is deficient from the erythrocyte membrane of patients suffering with Overhydrated Hereditary Stomatocytosis (OHSt).
Wilkinson, Dorothy Kate
core   +7 more sources

Lipid signalling in disease [PDF]

open access: yesNature Reviews Molecular Cell Biology, 2008
Signalling lipids such as eicosanoids, phosphoinositides, sphingolipids and fatty acids control important cellular processes, including cell proliferation, apoptosis, metabolism and migration. Extracellular signals from cytokines, growth factors and nutrients control the activity of a key set of lipid-modifying enzymes: phospholipases, prostaglandin ...
Wymann, M. P., Schneiter, R.
openaire   +5 more sources

Lipid signaling in plants [PDF]

open access: yesFrontiers in Plant Science, 2013
Membrane lipids provide both the structural basis for cell membranes and a rich source of cellular mediators that regulate many aspects of plant development and environmental interactions. Over recent years, lipids as hormones and signaling messengers have gained increasing attention in the plant biology community.
Wang, Xuemin, Chapman, Kent Dean
openaire   +3 more sources

Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding

open access: yesCells, 2021
SH3 domains constitute an important class of protein modules involved in a variety of cellular functions. They participate in protein-protein interactions via their canonical ligand binding interfaces composed of several evolutionarily conserved aromatic
Orsolya Tőke   +6 more
doaj   +1 more source

Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells

open access: yesJournal of Lipid Research, 2014
Cellular membranes are composed of numerous kinds of glycerophospholipids with different combinations of polar heads at the sn-3 position and acyl moieties at the sn-1 and sn-2 positions, respectively.
Daisuke Hishikawa   +3 more
doaj   +1 more source

Plasmalogens and Photooxidative Stress Signaling in Myxobacteria, and How it Unmasked CarF/TMEM189 as the Δ1′-Desaturase PEDS1 for Human Plasmalogen Biosynthesis

open access: yesFrontiers in Cell and Developmental Biology, 2022
Plasmalogens are glycerophospholipids with a hallmark sn-1 vinyl ether bond that endows them with unique physical-chemical properties. They have proposed biological roles in membrane organization, fluidity, signaling, and antioxidative functions, and ...
S. Padmanabhan   +8 more
doaj   +1 more source

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