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Chemical proteomics: a powerful tool for exploring protein lipidation [PDF]
, 2013 The study of post-translational modifications such as protein lipidation is a non-trivial challenge of the post-genomic era. In recent years the field of chemical proteomics has greatly advanced our ability to identify and quantify protein lipidation. In
Tate, EW, Serwa, RA, Storck, EM
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Biochemical and Structural Characterization of the Atg8/LC3 Lipidation Pathway [PDF]
, 2020 Atg8 and its eukaryotic orthologues LC3 and GARBARAP family proteins (referred here to Atg8 family proteins) play crucial roles in autophagy through their covalent ligation to lipids, typically phosphatidylethanolamine (PE), in a process known as ...
Zheng, Yumei
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Cell biology of protein–lipid conjugation
Cell Structure and Function, 2023 Protein–lipid conjugation is a widespread modification involved in many biological processes. Various lipids, including fatty acids, isoprenoids, sterols, glycosylphosphatidylinositol, sphingolipids, and phospholipids, are covalently linked with proteins.
Jun-ichi Sakamaki, Noboru Mizushima
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Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy
, 2021 Selective autophagy of damaged mitochondria, protein aggregates, and other cargoes is essential for health. Cargo initiates phagophore biogenesis, which entails the conjugation of LC3 to phosphatidylethanolamine.
Jensen, Liv E +6 more
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Molecules, 2019 N-Alkylation and N-acylation of the prostaglandin-F2α allosteric modulator l-PDC31 were performed to install various alkyl, PEG and isoprenoid groups onto the l-enantiomer of the peptide.
Julien Poupart +3 more
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Frontiers in Immunology, 2021 Phagocytosis is a receptor-mediated process used by cells to engulf a wide variety of particulates, including microorganisms and apoptotic cells. Many of the proteins involved in this highly orchestrated process are post-translationally modified with ...
Charneal L. Dixon +7 more
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International Journal of Molecular Sciences, 2013 Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices and machines derived from engineering, physics, materials science, chemistry and biology. These devices have found applications in biomedical sciences, such as targeted drug delivery, bio-imaging, sensing and diagnosis of pathologies at early stages.
S. Mashaghi (Samaneh) +3 more
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Global profiling of protein lipidation using chemical proteomic technologies [PDF]
, 2015 Protein lipidation is unique amongst post-translational modifications (PTMs) in enabling direct interaction with cell membranes, and is found in every form of life.
Storck, Elisabeth M. +7 more
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Lipids and lipid metabolism in the eye [PDF]
Journal of Lipid Research, 2009 The vertebrate eye is a complex sensory organ consisting of multiple, distinct tissues, each having its own unique biochemical composition, structure, and physiological function. Key among these are the retina, lens, and cornea, working in concert to bring photons of light into the eye, focus them correctly on the retina, and convert their energy into ...
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, 2003 From chapter introduction: Students entering the field of fish nutrition might be forgiven for forming two impressions. First, is the impression that because publications on lipids often dominate research journals and conference proceedings on fish nutrition, lipids are the most important nutrients for fish. They are not.
Sargent, John R +2 more
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