Results 11 to 20 of about 24,464,671 (254)

Lipocalin-2 and neutrophil activation in pancreatic cancer cachexia [PDF]

Frontiers in Immunology, 2023
BackgroundCancer cachexia is a multifactorial syndrome characterized by body weight loss and systemic inflammation. The characterization of the inflammatory response in patients with cachexia is still limited.
Min Deng, Merel R. Aberle, Annemarie A. J. H. M. van Bijnen, Gregory van der Kroft, Gregory van der Kroft, Kaatje Lenaerts, Ulf P. Neumann, Ulf P. Neumann, Georg Wiltberger, Frank G. Schaap, Frank G. Schaap, Steven W. M. Olde Damink, Steven W. M. Olde Damink, Sander S. Rensen   +13 more
doaj   +3 more sources

Lipocalin-2 is associated with FGF23 in WNT1 and PLS3 osteoporosis [PDF]

Frontiers in Endocrinology, 2022
BackgroundThe pathogenic mechanisms of early-onset osteoporosis caused by WNT1 and PLS3 mutations are incompletely understood and diagnostic biomarkers of these disorders are limited.
Petra Loid, Petra Loid, Petra Loid, Helena Hauta-alus, Helena Hauta-alus, Helena Hauta-alus, Helena Hauta-alus, Outi Mäkitie, Outi Mäkitie, Outi Mäkitie, Outi Mäkitie, Per Magnusson, Riikka E. Mäkitie, Riikka E. Mäkitie, Riikka E. Mäkitie   +14 more
doaj   +2 more sources

Lipocalin‐2—The myth of its expression and function [PDF]

Basic & Clinical Pharmacology & Toxicology, 2019
AbstractLipocalin‐2 is a functional biomarker for acute and chronic kidney diseases, heart failure and obesity‐related medical complications. It is rapidly induced in epithelial cells under stress conditions, but constitutively produced from pre‐adipocytes and mature adipocytes. Measuring the lipocalin‐2 levels represents an effective approach for risk
Dahui, Li, Wai, Yan Sun, Bowen, Fu, Aimin, Xu, Yu, Wang   +4 more
openaire   +3 more sources

Lipocalin-2 in Stroke

Neuro - Open Journal, 2015
Stroke is a leading cause of adult disability in the United States. However, limited number of molecularly targeted therapy exists for stroke. Recent studies have shown that Li-pocalin-2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and hemorrhagic strokes.
Chou, Wen-Hai, Wang, Guona, Kumar, Varun, Weng, Yi-Chinn   +3 more
openaire   +3 more sources

Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis [PDF]

Frontiers in Immunology, 2018
Lipocalin-2 is a constituent of the neutrophil secondary granules and is expressed de novo by macrophages and epithelium in response to inflammation. Lipocalin-2 acts in a bacteriostatic fashion by binding iron-loaded siderophores required for bacterial ...
Sara Louise Dahl, Joshua S. Woodworth, Christian Johann Lerche, Elisabeth Præstekjær Cramer, Pia Rude Nielsen, Claus Moser, Allan Randrup Thomsen, Niels Borregaard, Jack Bernard Cowland, Jack Bernard Cowland   +9 more
doaj   +2 more sources

Association of lipocalin-2 level, glycemic status and obesity in type 2 diabetes mellitus

BMC Research Notes, 2017
Background Management of type 2 diabetes mellitus aims to maintain a normal glycemic status, which if not, it may lead to acute and/or chronic diabetic complications.
Areej E. Elkhidir, Halima B. Eltaher, Abdelrahim O. Mohamed   +2 more
doaj   +2 more sources

Enhancers of cancer stem cells and epithelial–mesenchymal transition: Lin28, MUC1, and lipocalin-2 as a new prognostic axis in classical invasive lobular carcinoma of the breast

Polish Journal of Pathology
Breast carcinoma is one of the most common causes of cancer-related mortality among women worldwide. The primary objective of the present study was to eva­luate the expression of the epithelial-mesenchymal transition (EMT)-related markers Lin28, MUC1 ...
Mohamed Alabiad, Raja Aljafil, Amany Shalaby, Ahmed M. Yehia, Mohammed Alorini, Basma Hamed Ibrahim   +5 more
doaj   +2 more sources

Lipocalin-2, glucose metabolism and chronic low-grade systemic inflammation in Chinese people [PDF]

Cardiovascular Diabetology, 2012
Background Lipocalin-2 is a novel adipokine with connection to insulin resistance. In this study, we aimed to investigate the association of serum lipocalin-2 with glucose metabolism and other metabolic phenotype in a large-scale Chinese population ...
Huang Ying, Yang Zhen, Ye Zi, Li Qin, Wen Jie, Tao Xiaoming, Chen Lili, He Min, Wang Xuanchun, Lu Bin, Zhang Zhaoyun, Zhang Weiwei, Qu Shen, Hu Renming   +13 more
doaj   +2 more sources

Lipocalin‐2 as a prognostic biomarker and its association with systemic inflammation in small cell lung cancer

Thoracic Cancer
Background Systemic inflammation is believed to contribute to small cell lung cancer (SCLC) progression, but the underlying relationship remains unclear.
Se‐Il Go, Jung Wook Yang, Woo Je Lee, Eun Jeong Jeong, Sungwoo Park, Gyeong‐Won Lee   +5 more
doaj   +2 more sources

Neutrophil Gelatinase-associated Lipocalin Significantly Correlates with Ischemic Damage in Patients Undergoing Laparoscopic Partial Nephrectomy

Balkan Medical Journal, 2019
Background:Laparoscopic partial nephrectomy, which minimizes renal function loss due to its nephron sparing nature, has become a standard technique among many experienced centers worldwide for surgical treatment of localized kidney tumors.
Meltem Savran Karadeniz, Isbara Alp Enişte, Hayriye Şentürk Çiftçi, Sebahat Usta, Tzevat Tefik, Öner Şanlı, Kamil Pembeci, Kamil Mehmet Tuğrul   +7 more
doaj   +2 more sources