Results 31 to 40 of about 35,244 (209)

Lipocalin‐2—The myth of its expression and function [PDF]

Basic & Clinical Pharmacology & Toxicology, 2019
AbstractLipocalin‐2 is a functional biomarker for acute and chronic kidney diseases, heart failure and obesity‐related medical complications. It is rapidly induced in epithelial cells under stress conditions, but constitutively produced from pre‐adipocytes and mature adipocytes. Measuring the lipocalin‐2 levels represents an effective approach for risk
Dahui, Li, Wai, Yan Sun, Bowen, Fu, Aimin, Xu, Yu, Wang   +4 more
openaire   +2 more sources

Adipokines resistin and lipokalin-2 and its role in the pathogenesis of polycystic ovary syndrome and metabolic syndrome [PDF]

Medičnì Perspektivi, 2013
Adipose tissues hormones resistin and lipocalin -2 play an important role in the regulation of lipid and carbohydrate metabolism, inflammation and immune disorders, fertility and reproductive mechanisms.
Voronenko N.Yu.
doaj   +3 more sources

Lipocalin 2 links inflammation and ankylosis in the clinical overlap of inflammatory bowel disease (IBD) and ankylosing spondylitis (AS)

Arthritis Research & Therapy, 2020
Background Little is known about the mechanisms underlying the clinical overlap between gut inflammation and joint ankylosis, as exemplified by the concurrence of inflammatory bowel diseases (IBD) and ankylosing spondylitis (AS).
Aifeng Lin, Robert D. Inman, Catherine J. Streutker, Zhenbo Zhang, Kenneth P. H. Pritzker, Hing Wo Tsui, Florence W. L. Tsui   +6 more
doaj   +1 more source

Lipocalin 2 is protective against E. coli pneumonia

Respiratory Research, 2010
Background Lipocalin 2 is a bacteriostatic protein that binds the siderophore enterobactin, an iron-chelating molecule produced by Escherichia coli (E. coli) that is required for bacterial growth. Infection of the lungs by E.
Høiby Niels, Moser Claus, Porse Bo T, Ralfkiaer Elisabeth, Santoni-Rugiu Eric, Wu Hong, Borregaard Niels, Cowland Jack B   +7 more
doaj   +1 more source

Association between FGF19, FGF21 and lipocalin-2, and diabetes progression in PCOS

Endocrine Connections, 2021
Women with polycystic ovary syndrome (PCOS) have an increased risk of developing type 2 diabetes. FGF19, FGF21 and lipocalin-2 have emerged as important markers of metabolic risk.
Feifei Cheng, Noel Yat Hey Ng, Claudia Ha Ting Tam, Yuying Zhang, Cadmon King Poo Lim, Guozhi Jiang, Alex Chi Wai Ng, Tiffany Tse Ling Yau, Lai Ping Cheung, Aimin Xu, Juliana C N Chan, Ronald C W Ma   +11 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The association between the preoperative serum levels of lipocalin-2 and matrix metalloproteinase-9 (MMP-9) and prognosis of breast cancer

BMC Cancer, 2012
Background Although a number of experimental studies have suggested the role of lipocalin-2 (LCN2) and matrix metalloproteinase-9 (MMP-9) in breast cancer progression, limited numbers of epidemiological studies have examined the relationship between the ...
Sung Hyuna, Choi Ji-Yeob, Lee Sang-Ah, Lee Kyoung-Mu, Han Sohee, Jeon Sujee, Song Minkyo, Lee Yunhee, Park Sue K, Yoo Keun-Young, Noh Dong-Young, Ahn Sei-Hyun, Kang Daehee   +12 more
doaj   +1 more source

The Potential Role of Chemerin, Lipocalin 2, and Apelin in the Diagnosis and Pathophysiology of Gestational Diabetes Mellitus

Journal of Diabetes Research, 2021
The exact role of adipokines in the pathogenesis of gestational diabetes mellitus (GDM) still remains not fully clear, and multiple studies have analyzed their potential contribution to the pathophysiology of this pregnancy complication.
Radzisław Mierzyński, Elżbieta Poniedziałek-Czajkowska, Dominik Dłuski, Maciej Kamiński, Agnieszka Mierzyńska, Bożena Leszczyńska-Gorzelak   +5 more
doaj   +1 more source

Association of lipocalin-2 level, glycemic status and obesity in type 2 diabetes mellitus

BMC Research Notes, 2017
Background Management of type 2 diabetes mellitus aims to maintain a normal glycemic status, which if not, it may lead to acute and/or chronic diabetic complications.
Areej E. Elkhidir, Halima B. Eltaher, Abdelrahim O. Mohamed   +2 more
doaj   +1 more source

Lipocalin-2, glucose metabolism and chronic low-grade systemic inflammation in Chinese people

Cardiovascular Diabetology, 2012
Background Lipocalin-2 is a novel adipokine with connection to insulin resistance. In this study, we aimed to investigate the association of serum lipocalin-2 with glucose metabolism and other metabolic phenotype in a large-scale Chinese population ...
Huang Ying, Yang Zhen, Ye Zi, Li Qin, Wen Jie, Tao Xiaoming, Chen Lili, He Min, Wang Xuanchun, Lu Bin, Zhang Zhaoyun, Zhang Weiwei, Qu Shen, Hu Renming   +13 more
doaj   +1 more source