Results 51 to 60 of about 35,244 (209)

Lipocalin 2 as a clinical significance in rheumatoid arthritis

Central European Journal of Immunology, 2017
<b>Aim of the study</b>: In this study, serum lipokalin 2 (LCN-2) levels and its clinical and radiological significance in patients with rheumatoid arthritis was evaluated.<br /> <b>Material and methods</b>: The study enrolled 37 patients with RA and 34 healthy controls.
Arif Gulkesen, Gurkan Akgol, Ahmet K. Poyraz, Suleyman Aydin, Affan Denk, Tulay Yildirim, Arzu Kaya   +6 more
openaire   +3 more sources

Identification and validation of fecal complement component 3 and fibronectin as potential biomarkers for monitoring disease activity in ulcerative colitis based on a mouse model

Animal Models and Experimental Medicine, EarlyView.
This study demonstrated elevated levels of fecal component 3 (C3) and fibronectin (FN) in an ulcerative colitis (UC) mouse model. Importantly, fecal C3 exhibited a stronger correlation with disease activity than the clinically used fecal calprotectin (FC).
Yangyun Guo, Ziheng Yan, Jingyu Ye, Ruifu Yang, Yajun Song, Hui Yue, Yong Zhao   +6 more
wiley   +1 more source

Salivary lipocalin family proteins from Panstrongylus chinai, a vector of Chagas disease

Data in Brief, 2017
The dataset in this report is related to the research article with the title: “Salivary gland transcripts of the kissing bug, Panstrongylus chinai, a vector of Chagas disease” (Kato et al., 2017) [1].
Hirotomo Kato, Ryan C. Jochim, Eduardo A. Gomez, Shunsuke Tsunekawa, Jesus G. Valenzuela, Yoshihisa Hashiguchi   +5 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis

Data in Brief, 2017
The data presented in this brief report support the research article “Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis” [1, doi: 10.1016/j.bbadis.2017.04.006]. We tested whether the absence of Lipocalin-
Anastasia Asimakopoulou, Erawan Borkham-Kamphorst, Eddy Van de Leur, Ralf Weiskirchen   +3 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Lipocalin-2 expression and function in pancreatic diseases

Pancreatology, 2020
Lipocalin-2 (LCN2) is a secreted molecule, expressed in various cell types, that is involved in the progression of numerous diseases and disorders. The biological functions and expression levels of LCN2 in diseases including pancreatic cancer, pancreatitis (acute and chronic), and diabetes mellitus, suggest the potential role of LCN2 as a biomarker and/
Kristyn Gumpper, Andrew William Dangel, Valentina Pita-Grisanti, Somashekar G. Krishna, Luis F. Lara, Thomas Mace, Georgios I. Papachristou, Darwin L. Conwell, Phil A. Hart, Zobeida Cruz-Monserrate   +9 more
openaire   +3 more sources

Lipocalin-2 Is an Autocrine Mediator of Reactive Astrocytosis [PDF]

The Journal of Neuroscience, 2009
Astrocytes, the most abundant glial cell type in the brain, provide metabolic and trophic support to neurons and modulate synaptic activity. In response to a brain injury, astrocytes proliferate and become hypertrophic with an increased expression of intermediate filament proteins.
Shinrye, Lee, Jae-Yong, Park, Won-Ha, Lee, Ho, Kim, Hae-Chul, Park, Kiyoshi, Mori, Kyoungho, Suk   +6 more
openaire   +2 more sources

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Lipocalin-2 and iron trafficking in the tumor microenvironment

Pharmacological Research, 2017
Iron is an essential element for virtually all organisms. It facilitates cell proliferation and growth but also contributes to major hallmarks of cancer such as tumor initiation, growth, and metastasis. Often, iron handling of tumor cells is disturbed, with altered iron acquisition, efflux, and storage. Targeting perturbed iron metabolic pathways might
Michaela, Jung, Christina, Mertens, Rebekka, Bauer, Claudia, Rehwald, Bernhard, Brüne   +4 more
openaire   +2 more sources