Results 21 to 30 of about 24,464,671 (254)

The Role of Nitric Oxide, Lipocalin-2, and Proinflammatory Cytokines on Proteinuria and Insulin Resistance in Type 2 Diabetes Mellitus Subgroups [PDF]

International Journal of General Medicine
Chung Hyun Nahm,1 Moon Hee Lee,2 Noriyoshi Fujii,3 Tatsuyoshi Fujii,4 Jong Weon Choi1 1Department of Laboratory Medicine, College of Medicine, Inha University, Incheon, Republic of Korea; 2Department of Internal Medicine, College of Medicine, Inha ...
Nahm CH, Lee MH, Fujii N, Fujii T, Choi JW   +4 more
doaj   +1 more source

Expression of visfatin, lipocalin-2, adiponectin, and chemerin in breast cancer and their association with clinicopathological parameters. [PDF]

Arch Med Sci Atheroscler Dis
Introduction Breast cancer remains the most common malignancy in women worldwide, with prognosis influenced not only by tumor-intrinsic factors but also by the tumor microenvironment. Adipokines, including visfatin, lipocalin-2, adiponectin, and chemerin,
Tchabashvili L, Leivaditis V, Papadaki H, Kitsou KS, Zolota V, Argentou MI.   +5 more
europepmc   +2 more sources

Predictive and Prognostic Role of Lipocalin-2 Expression in Prostate Cancer and Its Association with Gleason Score

Prostate Cancer, 2021
Lipocalin-2 has an important role in tumor progression, invasion, and metastasis. However, its role in prostate cancer remains unclear. The objective of this study is to determine the expression level of lipocalin-2 in human prostate cancer tissues and ...
M. Hakan Ulusoy, Yalcin Cirak, Yasemen Adali   +2 more
doaj   +1 more source

Increased plasma lipocalin-2 levels correlate with disease severity and may be a marker of acute inflammatory response in patients with psoriasis

Dermatology Reports, 2022
Background: More than a skin disease, psoriasis is also considered a systemic disorder. Lipocalin- 2, an adipokine, may be a link between psoriasis and systemic inflammation.
Chuyen Thi Hong Nguyen, Oanh Phan Tram Nguyen   +1 more
doaj   +1 more source

Lipocalin 2 – mutation screen and serum levels in patients with anorexia nervosa or obesity and in lean individuals

Frontiers in Endocrinology, 2023
ContextThe bone-derived adipokine lipocalin-2 is relevant for body weight regulation by stimulating the leptin-melanocortin pathway.ObjectiveWe aimed to (i) detect variants in the lipocalin-2 gene (LCN2) which are relevant for body weight regulation and ...
Yiran Zheng, Yiran Zheng, Luisa Sophie Rajcsanyi, Luisa Sophie Rajcsanyi, Manuela Kowalczyk, Johanna Giuranna, Beate Herpertz-Dahlmann, Jochen Seitz, Martina de Zwaan, Wolfgang Herzog, Stefan Ehrlich, Stefan Ehrlich, Stephan Zipfel, Stephan Zipfel, Katrin Giel, Katrin Giel, Karin Egberts, Roland Burghardt, Manuel Föcker, Saad Al-Lahham, Johannes Hebebrand, Johannes Hebebrand, Dagmar Fuhrer, Dagmar Fuhrer, Susanne Tan, Denise Zwanziger, Triinu Peters, Triinu Peters, Anke Hinney, Anke Hinney   +29 more
doaj   +1 more source

Circulating lipocalin-2 and retinol-binding protein 4 are associated with intima-media thickness and subclinical atherosclerosis in patients with type 2 diabetes. [PDF]

PLoS ONE, 2013
The lipocalin family proteins, including lipocalin-2 and retinol-binding protein 4 (RBP4), are adipokines closely associated with obesity-related metabolic disorders.
Yang Xiao, Aimin Xu, Xiaoyan Hui, Pengcheng Zhou, Xing Li, Hui Zhong, Weili Tang, Gan Huang, Zhiguang Zhou   +8 more
doaj   +1 more source

Lipocalin‐2 mediates the rejection of neural transplants [PDF]

The FASEB Journal, 2021
Abstract Lipocalin‐2 (LCN2) has been implicated in promoting apoptosis and neuroinflammation in neurological disorders; however, its role in neural transplantation remains unknown. In this study, we cultured and differentiated Lund human mesencephalic (LUHMES) cells into human dopaminergic‐like neurons and found that LCN2 mRNA was ...
Yi‐Chinn Weng, Yu‐Ting Huang, I‐Chen Chiang, Pei‐Ju Tsai, Yu‐Wen Su, Wen‐Hai Chou   +5 more
openaire   +2 more sources

Hemorrhagic Fever with Renal Syndrome Patients Exhibit Increased Levels of Lipocalin-2, Endothelin-1 and NT-proBNP

Life, 2023
Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease caused by viruses of the Orthohantavirus genus. This syndrome is characterized by renal and cardiopulmonary implications detectable with different biomarkers. Here, we explored the
Lidija Cvetko Krajinović, Kristian Bodulić, Renata Laškaj, Branka Žibrat, Petra Svoboda Karić, Ivan-Christian Kurolt, Mihaela Kordun, Antea Topić, Rok Čivljak, Tomislava Skuhala, Alemka Markotić   +10 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

Hepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino, Salvatore Piano, Matteo Stenico, Marta Tonon, Alessandra Brocca, Valeria Calvino, Simone Incicco, Nicola Zeni, Roberta Gagliardi, Chiara Cosma, Martina Zaninotto, Patrizia Burra, Umberto Cillo, Daniela Basso, Paolo Angeli   +14 more
wiley   +1 more source