Results 111 to 120 of about 75,579 (341)

SERS‐AI‐LUA‐Driven Salivary Diagnosis of Head and Neck Cancer Using Graphene‐Assisted Plasmonic Nanocorals

Advanced Science, EarlyView.
The developed graphene‐assisted plasmonic nanocoral platform enables sensitive, label‐free surface‐enhanced Raman scattering analysis of salivary metabolites for head and neck cancer (HNC) detection. When combined with machine learning classification and nonnegative least squares‐based spectral deconvolution, this approach achieves 98% diagnostic ...
Hyo Jeong Seo, Boyou Heo, Jun‐Yeong Yang, Rowoon Park, Sung‐Gyu Park, Jiyoung Yeo, So Hee Park, Chan Kwon Jung, Min‐Young Lee, Jooin Bang, Jun‐Ook Park, Ho Sang Jung   +11 more
wiley   +1 more source

Lipogenesis in rabbit adipose tissue

Journal of Lipid Research, 1975
Previous reports that rabbit adipose tissue does not synthesize fatty acids at significant rates led us to study in detail the pathways of lipogenesis and glyceroneogenesis in this tissue. We found that rabbit adipose tissue has a low capacity for denovo fatty acid synthesis from glucose but a high capacity for synthesis from pyruvate and acetate.
openaire   +4 more sources

Advances in miRNA research: Unraveling the complexities of gene regulation

Animal Models and Experimental Medicine, EarlyView.
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley   +1 more source

FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1 [PDF]

, 2023
Sungyun Cho, Yujin Chun, Long He, Cuauhtemoc B. Ramirez, Kripa S. Ganesh, Kyungjo Jeong, Junho Song, Jin‐Gyu Cheong, Zhongchi Li, Jungmin Choi, Joo‐Hwan Kim, Nikos Koundouros, Fangyuan Ding, Noah Dephoure, Cholsoon Jang, John Blenis, Gina Lee   +16 more
openalex   +1 more source

Pharmacologic inhibition of lipogenesis for the treatment of NAFLD.

Journal of Hepatology, 2023
W. Esler, David E. Cohen
semanticscholar   +1 more source

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis

Nature Communications, 2019
Hepatic steatosis develops when lipid influx and production exceed the liver’s ability to utilize/export triglycerides. Obesity promotes steatosis and is characterized by leptin resistance. A role of leptin in hepatic lipid handling is highlighted by the
M. Hackl, C. Fürnsinn, C. Schuh, M. Krššák, F. Carli, Sara Guerra, A. Freudenthaler, S. Baumgartner-Parzer, T. Helbich, A. Luger, M. Zeyda, A. Gastaldelli, C. Buettner, T. Scherer   +13 more
semanticscholar   +1 more source

Innovative insights into the effects of a high‐sucrose diet on pancreatic health and the therapeutic role of empagliflozin in type 2 diabetes: An experimental study

Animal Models and Experimental Medicine, EarlyView.
Histologic assessment of pancreatic tissues using the H&E method (Scale bar = 100 μm. Images were captured at 400×). A high‐sucrose diet induced structural damage in pancreatic tissue, whereas empagliflozin treatment markedly improved these histological alterations.
Emad Gholami, Ali Fardin, Fazeleh Iranshahi, Alireza Malek, Ali Saravani, Faranaz Aghvami, Houman Parsaei, Habib Yaribeygi   +7 more
wiley   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, EarlyView.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Synergistic Effects of the Aerobic Training and Capsaicin on the Expression level of AMP-Activated Protein Kinase and Protein Kinase B Gene of Liver Tissue in Rat Fed a High-Fat Diet

Journal of Ardabil University of Medical Sciences, 2022
Background & objectives: Obesity and a high-fat diet (HFD) lead to metabolic disorders in the liver by affecting the signaling pathways of fat and glucose metabolism.
Ghasem Torabi Palat Kaleh, ABBAS Sadeghi, Ahmad Abdi   +2 more
doaj  

Multi‐Omics Insights Into the Role of Fructooligosaccharides Supplementation in Alleviating Salpingitis in Laying Hens

Animal Research and One Health, EarlyView.
Multi‐omics analysis revealed that FOS supplementation increased the abundance of Phascolarctobacterium, GCA‐900066575, Shuttleworthia, Olsenella, Eubacterium_hallii_group while decreasing Alistipes. It also influenced the metabolism of S‐lactoylglutathione, p‐cresol glucuronate, 2‐phenylethanol glucuronide, propionic acid, dulcitol, and inhibited the ...
Dan Song, Tao Duan, Rong Li, Xiaoqiu Wang, Fengdong Zhang, Jia Feng, Lin Qiao, Junlin Cheng, Lixian Chen, Aike Li, Yuna Min, Weiwei Wang   +11 more
wiley   +1 more source