Results 11 to 20 of about 51,491 (100)
NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA [PDF]
Lipids in Health and DiseaseBackground Metabolic dysfunction associated steatotic liver disease (MASLD), closely linked to excessive lipogenesis, induces chronic liver disease. MASLD often cause other metabolic diseases, such as cardiovascular disease, diabetes and obesity. However,
Zhouqi Wang +6 more
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Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis
Nature Communications, 2018 Insulin promotes lipogenesis but, on the other hand, insulin resistance is associated with increased lipogenesis in the liver. Here the authors show that Snail1 is upregulated by insulin and inhibits lipogenesis by repressing Fasn expression but insulin ...
Yan Liu +6 more
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Molecules, 2018 Conflicting results for morusin activity during adipogenic differentiation are reported in 3T3-L1 adipocytes and cancer cells. To elucidate the influence of morusin on fat metabolism, their anti-obesity effects and molecular mechanism were investigated ...
Mi Rim Lee +10 more
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Modulation of Lipogenesis and Glucose Consumption in HepG2 Cells and C2C12 Myotubes by Sophoricoside
Molecules, 2013 Sophoricoside, an isoflavone glycoside isolated from Sophora japonica (Leguminosae), has been widely reported as an immunomodulator. In this study, the effects of sophoricoside on lipogenesis and glucose consumption in HepG2 cells and C2C12 myotubes were
Chongming Wu +7 more
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Journal of Hepatocellular Carcinoma, 2021 Qian Liu,1 Xifeng Dong2 1Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300020, People’s Republic of China; 2Department of Hematology, Tianjin Medical University General Hospital, Tianjin 300020, People’s ...
Liu Q, Dong X
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Frontiers in Endocrinology, 2019 Exacerbated expansion of adipose tissue seen in diet-induced obesity leads to endocrine dysfunction and disturbance in adipokine secretion, with such abnormal profile positively associated with type 2 diabetes and other mild chronic inflammatory ...
Bruna K. S. Hirata +7 more
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The Role of Peptide Hormones in Insect Lipid Metabolism
Frontiers in Physiology, 2020 Lipids are the primary storage molecules and an essential source of energy in insects during reproduction, prolonged periods of flight, starvation, and diapause.
Umut Toprak
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Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock
Frontiers in Pharmacology, 2020 The circadian clock plays a key role in our daily physiology and metabolism. Alcohol consumption disrupts the circadian rhythm of metabolic genes in the liver; however, the potential contribution of circadian clock modulation to alcoholic liver disease ...
Youli Yao +8 more
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Fructose and Non-Alcoholic Steatohepatitis
Frontiers in Pharmacology, 2021 Background: The excessive consumption of free sugars is mainly responsible for the high prevalence of obesity and metabolic syndrome in industrialized countries.
Elke Roeb, Ralf Weiskirchen
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Journal of Lipid Research, 2022 In mothers who are nursing their infants, increased clearance of plasma metabolites into the mammary gland may reduce ectopic lipid in the liver.
Maria A. Ramos-Roman +5 more
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