Results 111 to 120 of about 46,973 (295)

Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance

open access: yesLipids in Health and Disease, 2011
Obese subjects with impaired glucose tolerance (IGT) are more susceptible than healthy individuals to oxidative stress and cardiovascular disease.
McNeilly Andrea M   +7 more
doaj   +1 more source

The Effect of Alpha Lipoic Acid in Preventing Atherosclerosis Lesion on the Abdominal Aorta of Diabetes Mellitus Type 2 Rats [PDF]

open access: yes, 2017
Various studies have studied the clinical use of alpha-lipoic acid (ALA) for treating diabetic complications. The protective effect of  lipoic acid in  atherosclerosis induced by diabetes mellitus type 2 (DM type 2)  still needs further ...
ismawati, I. (Ismawati)   +1 more
core  

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy

open access: yesBasic and Clinical Neuroscience, 2012
Introduction : Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory.
Narges Karimi   +3 more
doaj   +2 more sources

Inhibition of Pseudomonas aeruginosa biofilm formation by 2,2’-bipyridyl, lipoic, kojic and picolinic acids [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2015
Objective(s):The inhibitory effects of iron chelators, and FeCl3 chelation on biofilm formation and swarming motility were investigated against an opportunistic human pathogen Pseudomonas aeruginosa.
Kübra Çevik, Seyhan Ulusoy
doaj  

Gene Editing and Transformation Strategies for Engineering Drought‐Tolerant Legumes

open access: yesLegume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Legumes play a vital role in agriculture, nutrition, and the economy, but their production faces significant threats. Among these, drought and its unpredictability will be the most damaging constraint in the coming decades. Enhancing drought tolerance is essential for resilient and sustainable legume cultivation, and genetic engineering ...
Andrea Fernandez‐Gutierrez   +2 more
wiley   +1 more source

Lipoic acid and diabetes II: Mode of action of lipoic acid

open access: yesJournal of Biosciences, 1985
Intraperitoneal administration of lipoic acid (10 mg/100 g) does not effect changes in serum insulin levels in normal and alloxan diabetic rats, while normalising increased serum pyruvate, and impaired liver pyruvic dehydrogenase characteristic of the diabetic state.
V. M. Gandhi   +3 more
openaire   +1 more source

The Marriage of Metal Nanoclusters With Reticular Frameworks: Synthetic Strategies and Biomedical Applications

open access: yesAggregate, Volume 7, Issue 2, February 2026.
The integration of metal nanoclusters (MNCs) with reticular frameworks (RFs) has recently emerged as a powerful strategy to create composite materials with enhanced and synergistic functionalities. This review provides an overview of the synthetic strategies developed for constructing MNCs/RFs composites and their recent advances in biomedical ...
Wenfeng Liu   +3 more
wiley   +1 more source

Endothelial dysfunction in type 2 diabetes: effect of antioxidants [PDF]

open access: yes, 2007
Individuals with insulin resistance and diabetes mellitus have increased cardiovascular morbidity and mortality, caused in part by vascular complications. Endothelial dysfunction has been implicated in the pathogenesis of vascular diabetic disease.
Louro, T   +4 more
core  

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