Results 121 to 130 of about 40,812 (258)

Evolution of Thiosemicarbazones: From First‐ to Second‐Generation Metal Chelators and Their Reactive Oxygen Species‐Mediated Effects in Melanoma

ChemistryOpen, Volume 15, Issue 6, June 2026.
Thiosemicarbazones (TSC) have demonstrated promise as new chemotherapeutic agents against melanoma in both in vitro and In vivo studies. TSC are powerful metal coordinating agents, coordinating transition metal ions such as zinc, copper and iron in multiple oxidation states. It is this metal coordination that imparts the anticancer activity.
Rohina Alim, Scott D. Andrew, Christopher J. Parkinson   +2 more
wiley   +1 more source

The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy

Basic and Clinical Neuroscience, 2012
Introduction : Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory.
Narges Karimi, Mitra Kamran, Mehrdad Roghani, Tourandokht Baluchnejadmojarad   +3 more
doaj   +2 more sources

Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals

Aging Cell, Volume 25, Issue 6, June 2026.
Supplement users have lower epigenetic biological age than non‐users. Several supplements or supplement classes are associated with some benefit on epigenetic age in either cross‐sectional or longitudinal analyses. ABSTRACT In this cross‐sectional cohort we analyzed data from 4260 “health enthusiasts” who purchased at least one saliva‐based DNA ...
Kamil Pabis, Weilan Wang, Kumar Selvarajoo, Yelena V. Budovskaya, Vincenzo Sorrentino, Jan Gruber, Brian K. Kennedy   +6 more
wiley   +1 more source

Clinical Diabetic Peripheral Neuropathy: Can It Be Reversed? Arguments for and Against From a NEUROdiab Debate

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Diabetic peripheral neuropathy (DPN) is a prevalent and disabling complication of diabetes, yet whether established clinical DPN is reversible remains debated. At the 35th Annual Meeting of NEUROdiab, a formal debate examined arguments ‘for’ and ‘against’ the proposition that clinical DPN can be reversed.
Gordon Sloan, Shazli Azmi, Stephanie Eid, Maryam Ferdousi, Johan Røikjer, Zoltan Kender, Luca D'Onofrio, Eleni Karlafti, Brian Callaghan, Bruce A. Perkins   +9 more
wiley   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Bioinspired Microphase‐Engineered Binders for Silicon Anodes

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Inspired by the tough exoskeleton of Phloeodes diabolicus, a bio‐based binder featuring LRA–click chemistry and hierarchical crosslinking forms well‐defined microphase‐separated structures that enable robust silicon anodes. This system promotes the formation of a LiF–rich, ultrathin SEI (∼17 nm) with high modulus and ionic conductivity, ensuring long ...
Lirong Tang, Lan Zhao, Zhiyi Cao, Fengcai Lin, Biao Huang, Haijun Li, Lingling Qian, Yingshan Shi, Yaohang Weng, Xuan Yang, Hanyang Liu, Beili Lu, Jianhua Lv, Xinda You, Jiayu Tao, Zhenwei Wu   +15 more
wiley   +1 more source

On ultraviolet light and the origin of ribosomes [PDF]

Function of UV light in evolution of contemporary ...
Sagan, C., Shapshak, P.
core   +1 more source

Current experience in testing mitochondrial nutrients in disorders featuring oxidative stress and mitochondrial dysfunction: rational design of chemoprevention trials [PDF]

, 2014
An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, mitochondrial cofactors termed “mitochondrial nutrients” (MN), such as α-lipoic acid (ALA), Coenzyme Q10 (CoQ10), and l-carnitine ...
Castello, Giuseppe, Cordero Morales, Mario David, d'Ischia, Marco, Gadaleta, Maria Nicola, Pagano, Giovanni, Talamanca, Annita Aiello   +5 more
core  

Note for Male Smokers: The Healthy Eating Index Associated With the Risk of Subclinical Myocardial Injury

Clinical Cardiology, Volume 49, Issue 5, May 2026.
Flow chart of the study population. ABSTRACT Objectives To investigate the associations of the healthy eating index (HEI) and subclinical myocardial injury (SCMI) in different smoking statuses (current smokers, former smokers, and never smokers) based on the National Health and Nutrition Examination Survey (NHANES) III.
Zhi‐jin Li, Bin‐gui Li
wiley   +1 more source