Results 141 to 150 of about 2,527,105 (193)
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Alpha lipoic acid for dementia
Cochrane Database of Systematic Reviews, 2002Oxidative processes have been implicated in the pathogenesis of neurodegenerative dementias including Alzheimer's disease. Protecting the central nervous system against these damaging mechanisms may be a useful therapeutic approach. Alpha lipoic acid (ALA) is an endogenous antioxidant that interrupts cellular oxidative processes in both its oxidized ...
Anthony Klugman +3 more
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Lipoic acid biosynthesis defects
Journal of Inherited Metabolic Disease, 2014AbstractLipoate is a covalently bound cofactor essential for five redox reactions in humans: in four 2‐oxoacid dehydrogenases and the glycine cleavage system (GCS). Two enzymes are from the energy metabolism, α‐ketoglutarate dehydrogenase and pyruvate dehydrogenase; and three are from the amino acid metabolism, branched‐chain ketoacid dehydrogenase, 2 ...
Johannes A, Mayr +4 more
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2008
Discovery molecular structure A Trail of Research on Lipoic Acid, L.J. Reed Lipoic Acid Biosynthesis, N.M. Nesbitt, R.M. Cicchillo, K.H. Lee, T.L. Grove, and S.J. Booker The Search for Potent alpha-lipoic Acid Derivatives: Chemical and Pharmacological Aspects, M. Ben Yakir, Y. Katzhendler, and S.
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Discovery molecular structure A Trail of Research on Lipoic Acid, L.J. Reed Lipoic Acid Biosynthesis, N.M. Nesbitt, R.M. Cicchillo, K.H. Lee, T.L. Grove, and S.J. Booker The Search for Potent alpha-lipoic Acid Derivatives: Chemical and Pharmacological Aspects, M. Ben Yakir, Y. Katzhendler, and S.
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The Biosynthesis of Lipoic Acid in the Rat
1980Lipoic acid is widely distributed among microorganisms, plants and animals (1–4). The concentration of this co- factor in animal tissues is quite low (5). It is mainly found in a form bound covalently to the α-ketoacid dehydrogenase multienzyme complexes. Nutritional experiments with higher animals have failed to demonstrate a growth response to lipoic
S. Dupre +4 more
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Alpha lipoic acid intoxicatıon: An adult
The American Journal of Emergency Medicine, 2018Alpha lipoic acid (ALA) is a potent antioxidant used to treat a variety of disorders. Although ALA is considered a very safe supplement and intoxication is very rare, acute high-dose ingestions can cause mortality. In this report, we discuss a very rare case of ALA intoxication to increase awareness of this issue.A 22-year-old female was referred to ...
FEREK EMİR, DUYGU +2 more
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Biosynthesis of biotin and lipoic acid
2001The genetics and mechanistic enzymology of biotin biosynthesis have been the subject of much investigation in the last decade, owing to the interest for biotin production by fermentation, on the one hand, and for the design of inhibitors with potential herbicidal properties, on the other hand.
A, Marquet, B T, Bui, D, Florentin
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2015
Lipoic acid, which is defined as a miralce antioxidan, is used by many departments. Eventhough clinical using data are very limited , it is used in treatment of diabetic neuropathy, physical therapy and rehabilitation clinic, dermatology clinic, geriatric clinics. It has usage area for cosmetic purposes.
TETİKÇOK, Ramazan +5 more
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Lipoic acid, which is defined as a miralce antioxidan, is used by many departments. Eventhough clinical using data are very limited , it is used in treatment of diabetic neuropathy, physical therapy and rehabilitation clinic, dermatology clinic, geriatric clinics. It has usage area for cosmetic purposes.
TETİKÇOK, Ramazan +5 more
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Arbor Clinical Nutrition Updates, 2006
In a nutshellALA is a powerful antioxidant, both water and lipid soluble, that can also regenerate other antioxidants.A range of ‘antioxidant’ and other clinical indications (such as chelating toxic metals) have been tested in small, open trials and/or animal studies.
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In a nutshellALA is a powerful antioxidant, both water and lipid soluble, that can also regenerate other antioxidants.A range of ‘antioxidant’ and other clinical indications (such as chelating toxic metals) have been tested in small, open trials and/or animal studies.
openaire +1 more source