Results 191 to 200 of about 40,812 (258)

Silymarin-alpha lipoic acid and metabolic dysfunction-associated steatotic liver disease: Insights and methodological considerations. [PDF]

World J Hepatol
Martínez-Sánchez FD, Martínez-Vázquez SE, Gutiérrez-Monterrubio R, Muñoz-Martínez S, Garcia-Juarez I.   +4 more
europepmc   +1 more source

Manifold hepatoprotective actions of α-lipoic acid on metabolic function through redox regulation, inflammatory modulation, and anti-apoptosis after chronic sleep-deprived injury. [PDF]

Front Nutr
Chang HM, Lin HC, Renn TY, Liu YC, Yen KJ, Liao CK, Tikhonova MA, Amstislavskaya TG, Singh SK, Chen LY.   +9 more
europepmc   +1 more source

Lipoic acid-kaempferol hydrogel loaded with Typhaneoside for sutureless wound closure, hemostasis, and healing of diabetic infected wounds. [PDF]

Mater Today Bio
Lu Q, Tang X, Huang K, Hu S, Tao B, Geng W, Lei Y, Guo A, Li K.   +8 more
europepmc   +1 more source

Effects of Preventive Exposure to High Doses of Alpha-Lipoic Acid (ALA) on Testicular and Sperm Alterations Caused by Scrotal Heat Shock in Mice. [PDF]

Biology (Basel)
Santos LC, Kersul MG, Machado WM, Cordeiro JMDA, Santos BR, Oliveira CL, Oliveira CS, Santana LR, Silva JF, Snoeck PPDN.   +9 more
europepmc   +1 more source

Alpha-lipoic acid reduces oxidative damage and ameliorates follicular abnormalities in vitrified cat ovarian tissue. [PDF]

Front Endocrinol (Lausanne)
Yin S, Li F, Pan Z, Bao H, Liu X.
europepmc   +1 more source

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Lipoic acid and lipoic acid analogs in cancer metabolism and chemotherapy

Expert Review of Clinical Pharmacology, 2014
The lipoic acid (lipoate) coenzyme is unique in all of mammalian metabolism. It is not only crucial to the function of some of the major enzymes feeding carbon into the tricarboxylic acid cycle, but also generates dynamic regulatory information about the metabolic status of the mitochondrial matrix, ultimately functioning to control these metabolic ...
Paul M Bingham, Zuzana Zachar
exaly   +3 more sources

Lipoic acid: A multifunctional antioxidant

BioFactors, 2003
Lipoic acid: a multifunctional ...
Bast, A., Haenen, G.R.M.M.
openaire   +4 more sources

The pharmacology of the antioxidant lipoic acid

General Pharmacology, 1997
1. Lipoic acid is an example of an existing drug whose therapeutic effect has been related to its antioxidant activity. 2. Antioxidant activity is a relative concept: it depends on the kind of oxidative stress and the kind of oxidizable substrate (e.g., DNA, lipid, protein). 3.
Guido R M M Haenen, Aalt Bast
exaly   +4 more sources

Lipoic acid metabolism in the rat

Archives of Biochemistry and Biophysics, 1976
Abstract dl-[1,6-14C]Lipoic acid was administered by intraperitoneal injection to rats at the level of 0.5 mg/100 g body weight. Approximately 56% of the radioactivity was recovered in the urine. When acidified and extracted with benzene, 92% of the radioactivity remained in the aqueous phase.
J T, Spence, D B, McCormick
openaire   +2 more sources

Alpha lipoic acid for dementia

Cochrane Database of Systematic Reviews, 2002
Oxidative processes have been implicated in the pathogenesis of neurodegenerative dementias including Alzheimer's disease. Protecting the central nervous system against these damaging mechanisms may be a useful therapeutic approach. Alpha lipoic acid (ALA) is an endogenous antioxidant that interrupts cellular oxidative processes in both its oxidized ...
Anthony Klugman, Justin Sauer, Naji Tabet, Robert Howard   +3 more
openaire   +2 more sources