Results 201 to 210 of about 40,812 (258)
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Electrochemical Determination of Lipoic Acid
Journal of Analytical Chemistry, 2004Procedures for determining lipoic acid by voltammetry and coulometric titration with electrogenerated halogens using the biamperometric indication of the titration end-point were developed. Possible mechanisms of lipoic acid oxidation with electrogenerated halogens are discussed.
Ziyatdinova G. +2 more
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Lipoic acid biosynthesis defects
Journal of Inherited Metabolic Disease, 2014AbstractLipoate is a covalently bound cofactor essential for five redox reactions in humans: in four 2‐oxoacid dehydrogenases and the glycine cleavage system (GCS). Two enzymes are from the energy metabolism, α‐ketoglutarate dehydrogenase and pyruvate dehydrogenase; and three are from the amino acid metabolism, branched‐chain ketoacid dehydrogenase, 2 ...
Johannes A, Mayr +4 more
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Multifunctional Lipoic Acid Conjugates
Current Medicinal Chemistry, 2009Several hundreds of studies published the last decade have reported that alpha-lipoic acid (LA) possess the potential to intervene in various therapeutically interesting pathways. However, it should be noted that LA reportedly exerts most of its effects at high micromolar concentrations; that amides of LA exhibit higher biological activity than the ...
Koufaki, Maria, Detsi, A., Kiziridi, C.
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Journal of Agricultural and Food Chemistry, 1994
Lipoic acid was found to be present at low levels in wheat germ (ca. 0.1 ppm) but was not detected in flour or semolina. The reduced form of lipoic acid provided the reducing equivalents for thioredoxin in the reduction of proteins of wheat endosperm (albumins, globulins, gliadins, and glutenins).
Vianey-Liaud, N. +4 more
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Lipoic acid was found to be present at low levels in wheat germ (ca. 0.1 ppm) but was not detected in flour or semolina. The reduced form of lipoic acid provided the reducing equivalents for thioredoxin in the reduction of proteins of wheat endosperm (albumins, globulins, gliadins, and glutenins).
Vianey-Liaud, N. +4 more
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The Biosynthesis of Lipoic Acid in the Rat
1980Lipoic acid is widely distributed among microorganisms, plants and animals (1–4). The concentration of this co- factor in animal tissues is quite low (5). It is mainly found in a form bound covalently to the α-ketoacid dehydrogenase multienzyme complexes. Nutritional experiments with higher animals have failed to demonstrate a growth response to lipoic
S. Dupre +4 more
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Alpha lipoic acid intoxicatıon: An adult
The American Journal of Emergency Medicine, 2018Alpha lipoic acid (ALA) is a potent antioxidant used to treat a variety of disorders. Although ALA is considered a very safe supplement and intoxication is very rare, acute high-dose ingestions can cause mortality. In this report, we discuss a very rare case of ALA intoxication to increase awareness of this issue.A 22-year-old female was referred to ...
ÖZTURAN, İBRAHİM ULAŞ +2 more
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Biosynthesis of biotin and lipoic acid
2001The genetics and mechanistic enzymology of biotin biosynthesis have been the subject of much investigation in the last decade, owing to the interest for biotin production by fermentation, on the one hand, and for the design of inhibitors with potential herbicidal properties, on the other hand.
A, Marquet, B T, Bui, D, Florentin
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2008
Discovery molecular structure A Trail of Research on Lipoic Acid, L.J. Reed Lipoic Acid Biosynthesis, N.M. Nesbitt, R.M. Cicchillo, K.H. Lee, T.L. Grove, and S.J. Booker The Search for Potent alpha-lipoic Acid Derivatives: Chemical and Pharmacological Aspects, M. Ben Yakir, Y. Katzhendler, and S.
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Discovery molecular structure A Trail of Research on Lipoic Acid, L.J. Reed Lipoic Acid Biosynthesis, N.M. Nesbitt, R.M. Cicchillo, K.H. Lee, T.L. Grove, and S.J. Booker The Search for Potent alpha-lipoic Acid Derivatives: Chemical and Pharmacological Aspects, M. Ben Yakir, Y. Katzhendler, and S.
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2015
Lipoic acid, which is defined as a miralce antioxidan, is used by many departments. Eventhough clinical using data are very limited , it is used in treatment of diabetic neuropathy, physical therapy and rehabilitation clinic, dermatology clinic, geriatric clinics. It has usage area for cosmetic purposes.
TETİKÇOK, Ramazan +5 more
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Lipoic acid, which is defined as a miralce antioxidan, is used by many departments. Eventhough clinical using data are very limited , it is used in treatment of diabetic neuropathy, physical therapy and rehabilitation clinic, dermatology clinic, geriatric clinics. It has usage area for cosmetic purposes.
TETİKÇOK, Ramazan +5 more
openaire +1 more source
Arbor Clinical Nutrition Updates, 2006
In a nutshellALA is a powerful antioxidant, both water and lipid soluble, that can also regenerate other antioxidants.A range of ‘antioxidant’ and other clinical indications (such as chelating toxic metals) have been tested in small, open trials and/or animal studies.
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In a nutshellALA is a powerful antioxidant, both water and lipid soluble, that can also regenerate other antioxidants.A range of ‘antioxidant’ and other clinical indications (such as chelating toxic metals) have been tested in small, open trials and/or animal studies.
openaire +1 more source