Results 71 to 80 of about 2,527,105 (193)

Chlamydia trachomatis Serovar L2 Can Utilize Exogenous Lipoic Acid through the Action of the Lipoic Acid Ligase LplA1

, 2010
Lipoic acid is an essential protein bound cofactor that is vital for the functioning of several important enzymes involved in central metabolism. Genomes of all sequenced chlamydiae show the presence of two genes encoding lipoic acid ligases and one gene
Aishwarya V. Ramaswamy, Anthony T. Maurelli   +1 more
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Lipoic acid biosynthesis and lipoyl-protein assembly.

, 2014
In E. coli (green sequence), octanoate is transfered from ACP to the E2 subunit of pyruvate dehydrogenase (PDH) by LipB, followed by sulfuration to lipoic acid by LipA. In E.
Rogier Braakman (170571), Eric Smith (75971)   +1 more
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Inhibition of Pseudomonas aeruginosa biofilm formation by 2,2’-bipyridyl, lipoic, kojic and picolinic acids [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s):The inhibitory effects of iron chelators, and FeCl3 chelation on biofilm formation and swarming motility were investigated against an opportunistic human pathogen Pseudomonas aeruginosa.
Kübra Çevik, Seyhan Ulusoy
doaj  

Lipoic Acid Supplementation in the Ovariectomized Ewe [PDF]

, 2011
Inadequate concentrations of progesterone during gestation can result in impaired embryonic growth and losses. These losses may be attributed to an overactive mechanism of progesterone catabolism or improper luteal function, which results in low ...
Mottet, Rachel Susan
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Alpha-lipoic acid in liver metabolism and disease.

, 1998
R-alpha-Lipoic acid is found naturally occurring as a prosthetic group in alpha-keto acid dehydrogenase complexes of the mitochondria, and as such plays a fundamental role in metabolism.
L. Packer, B. H. Rihn, H. J. Tritschler, MARCOCCI, Lucia, J. K. Lodge, J. Bustamante   +5 more
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The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy

Basic and Clinical Neuroscience, 2012
Introduction : Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory.
Narges Karimi, Mitra Kamran, Mehrdad Roghani, Tourandokht Baluchnejadmojarad   +3 more
doaj   +2 more sources

Alpha-lipoic acid, an anti-obesity agent?

, 2004
Obesity shortens life expectancy and is a risk factor for hypertension and Type 2 diabetes. When added to the standard chow of Sprague-Dawley or Otsuka Long-Evans Tokushima Fatty rats, alpha-lipoic acid (0.5% weight/weight) reduced body weight and food ...
Doggrell, Sheila A
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α-lipoic acid suppresses neuronal excitability and attenuates colonic hypersensitivity to colorectal distention in diabetic rats

, 2017
Yan Sun,1,* Pan-Pan Yang,1,* Zhen-Yuan Song,2 Yu Feng,1 Duan-Min Hu,1 Ji Hu,1 Guang-Yin Xu,3 Hong-Hong Zhang1,3 1Department of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 2Department of ...
Hu DM, Yang PP, Zhang HH, Hu J, Song ZY, Feng Y, Xu GY, Sun Y   +7 more
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Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells.
3750, Kenzo, Uehira, Akiko, Kawabe, Masahito, Suiko, 3748, Kentaro, Nishimoto, Harishkumar, Madhyastha, 3749, Yoichi, Sakakibara, Kazuo, Nishiyama, Taiji, Suda, Masao, Yamasaki, Takeaki, Okamoto, 3751, 3742, 3743, 3744, 3745, 3746, 3747   +19 more
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Studies on the biosynthesis of lipoic acid

, 1984
A rapid, chemical method for the detection and quantitation of Iipoic acid has been developed. Lipoic acid produces a yellow color when reacted with PdCl₄⁻² in 1 N HCI.
Wolfe, Henry R.
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