Results 81 to 90 of about 40,812 (258)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Effects of R-Alpha Lipoic Acid on HbA1c, Lipids and Blood Pressure in Type-2 Diabetics: A Preliminary Study [PDF]

, 2009
R-alpha lipoic acid (R-ALA) supplementation improves blood glucose in diabetic animals, but there have been no long-term clinical trials in humans testing its use for glucose control (HbA1c).
Hoffman, Elisa, Lukaszuk, Judith, Prawitz, Aimee D., Schultz, Theresa M.   +3 more
core   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Effects of α-Lipoic Acid Supplementation on Growth Performance, Liver Histology, Antioxidant and Related Genes Expression of Hybrid Grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂)

Antioxidants
This study aimed to assess the impact of α-lipoic acid on the growth performance, antioxidant capacity and immunity in hybrid groupers (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus) fed with a high-lipid diet.
Weibin Huang, Tao Li, Wenshan Cai, Hengyang Song, Hao Liu, Beiping Tan, Shuang Zhang, Menglong Zhou, Yuanzhi Yang, Xiaohui Dong   +9 more
doaj   +1 more source

Evidence of a metabolic memory to early-life dietary restriction in male C57BL/6 mice [PDF]

, 2012
<p>Background: Dietary restriction (DR) extends lifespan and induces beneficial metabolic effects in many animals. What is far less clear is whether animals retain a metabolic memory to previous DR exposure, that is, can early-life DR preserve ...
A Ceriello, A Dubey, A Nakamura, A Taguchi, BJ Merry, BJ Merry, BP Yu, BS Hass, C Hambly, C Messier, C Selman, C Selman, CK Lee, CK Lee, DP Argentino, EP Weiss, F Capstick, H Maeda, J Cantley, J Jacobson, JD Mulligan, JF Clinthorne, JM Dhahbi, JM Dhahbi, JR Mitchell, JR Speakman, L Fontana, LK Heilbronn, LM Redman, MJ Forster, MJ Forster, R Weindruch, R Weindruch, RJ Colman, RM Anson, S Goto, S Hempenstall, S Keipert, S Park, S Rezzi, SK Barnes, SL Johnston, SS Jessani, SX Cao, TM Wallace, W Mair, X Li   +46 more
core   +1 more source

Mechanical stability in flexible perovskite solar cells: Interface engineering and device design

FlexMat, EarlyView.
Statistics of the improvement methods for f‐PSCs. Abstract Flexible perovskite solar cells (f‐PSCs) demonstrate significant potential for application in next‐generation wearable electronic devices and photovoltaic building integration due to their high power conversion efficiency and excellent power‐to‐weight ratio. However, the inherent brittleness of
Hong‐Yi Hou, Xin‐Yi Zeng, Jian‐Xin Tang, Yan‐Qing Li   +3 more
wiley   +1 more source

Alpha lipoic acid efficacy in burning mouth syndrome: a controlled clinical trial [PDF]

, 2015
Background: A double-blind placebo-controlled trial was conducted in order to evaluate the efficacy of alpha lipoic acid (ALA) and determine the statistical significance of the outcome variables.
Cerero Lapiedra, Rocío, Esparza Gómez, Germán Carlos, Llamas Martínez, Silvia, Moreno López, Luis Alberto, Palacios Sánchez, Begoña   +4 more
core   +2 more sources

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

THE COMBINATION OF α-LIPOIC ACID INTAKE WITH ECCENTRIC EXERCISE MODULATES ERYTHROPOIETIN RELEASE

Biology of Sport, 2014
The generation of reactive nitrogen/oxygen species (RN/OS) represents an important mechanism in erythropoietin (EPO) expression and skeletal muscle adaptation to physical and metabolic stress.
B. Morawin, D. Turowski, M. Naczk, I. Siatkowski, A. Zembron-Lacny   +4 more
doaj   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source