Results 1 to 10 of about 144,905 (388)

Gut microbiome is linked to functions of peripheral immune cells in transition cows during excessive lipolysis

Microbiome, 2023
Background Postpartum dairy cows experiencing excessive lipolysis are prone to severe immunosuppression. Despite the extensive understanding of the gut microbial regulation of host immunity and metabolism, its role during excessive lipolysis in cows is ...
Fengfei Gu, Senlin Zhu, Yifan Tang, Xiaohan Liu, Minghui Jia, Nilusha Malmuthuge, Teresa G. Valencak, Joseph W. McFadden, Jian-Xin Liu, Hui-Zeng Sun   +9 more
doaj   +2 more sources

The Molecular Brakes of Adipose Tissue Lipolysis

Frontiers in Physiology, 2022
Adaptation to changes in energy availability is pivotal for the survival of animals. Adipose tissue, the body’s largest reservoir of energy and a major source of metabolic fuel, exerts a buffering function for fluctuations in nutrient availability.
Yongguo Li, Zhen Li, Devi Anggraini Ngandiri, Mireia Llerins Perez, Alexander Wolf, Yuanyuan Wang   +5 more
doaj   +2 more sources

Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia

Cell Death and Disease, 2021
Cancer cachexia is a metabolic disorder characterized by skeletal muscle wasting and white adipose tissue browning. Specific functions of several hormones, growth factors, and cytokines derived from tumors can trigger cachexia.
Wenjun Hu, Hairong Xiong, Zeyuan Ru, Yan Zhao, Yali Zhou, Kairu Xie, Wen Xiao, Zhiyong Xiong, Cheng Wang, Changfei Yuan, Jian Shi, Quansheng Du, Xiaoping Zhang, Hongmei Yang   +13 more
doaj   +2 more sources

Dependence of rates of lipolysis, esterification, and free fatty acid release in isolated fat cells on age, cell size, and nutritional state

Journal of Lipid Research, 1973
Rates of lipolysis, esterification, and free fatty acid release were estimated in isolated epididymal fat cells prepared from rats fed either ad lib. or with a restricted caloric intake.
Michael F. Reardon, R. Brian Goldrick, Noel H. Fidge   +2 more
doaj   +2 more sources

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis. [PDF]

PLoS ONE, 2016
OBJECTIVES:Numerous genetic loci have been associated with measures of central fat accumulation, such as waist-to-hip ratio adjusted for body mass index (WHRadjBMI).
Rona J Strawbridge, Helmut Laumen, Anders Hamsten, Michaela Breier, Harald Grallert, Hans Hauner, Peter Arner, Ingrid Dahlman   +7 more
doaj   +7 more sources

Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice

Frontiers in Physiology, 2018
Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis.Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice. The effects of
Qun Du, Shuihong Zhang, Aiyun Li, Imran S. Mohammad, Baolin Liu, Yanwu Li   +5 more
doaj   +2 more sources

Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits

bioRxiv, 2022
To investigate roles for bone marrow adipocyte (BMAd) lipolysis in bone homeostasis, we created a BMAd-specific Cre mouse model in which we knocked out adipose triglyceride lipase (ATGL, Pnpla2).
Ziru Li, E. Bowers, Junxiong Zhu, Hui Yu, Julie Hardij, Devika P. Bagchi, H. Mori, Kenneth T. Lewis, Katrina Granger, Rebecca L. Schill, Steven M. Romanelli, Simin H. Abrishami, K. Hankenson, K. Singer, C. Rosen, O. MacDougald   +15 more
semanticscholar   +1 more source

Phospholipid Degradation Kinetics of Pork during Combined High-Pressure and Thermal Treatments [PDF]

Shipin Kexue, 2023
In order to explore the effect of combined high-pressure and thermal treatment on the lipolysis of phospholipids in pork, the phospholipid degradation kinetics of pork was studied in the 300 to 700 MPa pressure range and in the 20 to 60 ℃ temperature ...
YUN Zhoumiao, HUANG Yechuan, PENG Chunlei, ZHAO Jing, ZHANG Keyuan
doaj   +1 more source

β3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis

JCI Insight, 2021
β3-Adrenergic receptors (β3-ARs) are the predominant regulators of rodent brown adipose tissue (BAT) thermogenesis. However, in humans, the physiological relevance of BAT and β3-AR remains controversial.
C. Cero, H. Lea, K. Zhu, F. Shamsi, Y. Tseng, A. Cypess   +5 more
semanticscholar   +1 more source

Brain insulin signaling suppresses lipolysis in the absence of peripheral insulin receptors and requires the MAPK pathway

Molecular Metabolism, 2023
Objectives: Insulin's ability to counterbalance catecholamine-induced lipolysis defines insulin action in adipose tissue. Insulin suppresses lipolysis directly at the level of the adipocyte and indirectly through signaling in the brain.
Matthäus Metz, James O'Hare, Bob Cheng, Michelle Puchowicz, Christoph Buettner, Thomas Scherer   +5 more
doaj   +1 more source