Results 61 to 70 of about 86,531 (200)

Adipose tissue lipolysis and remodeling during the transition period of dairy cows

Journal of Animal Science and Biotechnology, 2017
Elevated concentrations of plasma fatty acids in transition dairy cows are significantly associated with increased disease susceptibility and poor lactation performance.
G. Contreras, C. Strieder-Barboza, W. Raphael   +2 more
semanticscholar   +1 more source

Modulation of lipolysis and glycolysis pathways in cancer stem cells changed multipotentiality and differentiation capacity toward endothelial lineage

Cell & Bioscience, 2019
Cancer stem cells obtain energy demand through the activation of glycolysis and lipolysis. It seems that the use of approached targeting glycolysis and lipolysis could be an effective strategy for the inhibition of cancer stem cells.
Ayda Pouyafar, Milad Zadi Heydarabad, Jalal Abdolalizadeh, Reza Rahbarghazi, Mehdi Talebi   +4 more
doaj   +1 more source

Hormone-stimulated lipolysis in isolated fat cells from “young” and “old” rats

Journal of Lipid Research, 1973
The biphasic nature of the lipolytic dose-response curve of epinephrine in fat cells from “young” rats (40–45 days) was confirmed. The first phase (Lipolysis I) occurred at concentrations of from 10–7 m to 3 × 10–6 m.
Elizabeth A. Miller, Donald O. Allen
doaj  

Copper Regulates Cyclic AMP-Dependent Lipolysis

Nature Chemical Biology, 2016
Cell signaling relies extensively on dynamic pools of redox-inactive metal ions such as sodium, potassium, calcium, and zinc, but their redox-active transition metal counterparts such as copper and iron have been studied primarily as static enzyme ...
Lakshmi Krishnamoorthy, J. Cotruvo, J. Chan, H. Kaluarachchi, A. Muchenditsi, Venkata S. Pendyala, Shang Jia, Allegra T. Aron, Cheri M Ackerman, M. V. Wal, Timothy Guan, Lukas P Smaga, Samouil L. Farhi, Elizabeth J. New, S. Lutsenko, Christopher J. Chang   +15 more
semanticscholar   +1 more source

Effect of epinephrine and other lipolytic agents on intracellular lipolysis and lipoprotein lipase activity in 3T3-L1 adipocytes.

Journal of Lipid Research, 1987
3T3-L1 adipocytes were used to test the hypothesis that hormone-sensitive lipolysis and lipoprotein lipase activity might be regulated in a reciprocal manner.
S S Chernick, P M Spooner, M M Garrison, R O Scow   +3 more
doaj  

Pharmacological inhibition of lipolysis prevents adverse metabolic outcomes during glucocorticoid administration

Molecular Metabolism, 2023
Objective: Glucocorticoids are one of the most commonly prescribed classes of anti-inflammatory drugs; however, chronic treatment promotes iatrogenic (drug-induced) diabetes.
Melissa A. Linden, Susan J. Burke, Humza A. Pirzadah, Tai-Yu Huang, Heidi M. Batdorf, Walid K. Mohammed, Katarina A. Jones, Sujoy Ghosh, Shawn R. Campagna, J. Jason Collier, Robert C. Noland   +10 more
doaj  

Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function

Nature Communications, 2016
Dysfunctional cellular lipid metabolism contributes to common chronic human diseases, including type 2 diabetes, obesity, fatty liver disease and diabetic cardiomyopathy.
Violeta I Gallardo-Montejano, Geetu Saxena, C. Kusminski, Chaofeng Yang, John L. McAfee, L. Hahner, Kathleen M. Hoch, William Dubinsky, V. Narkar, P. Bickel   +9 more
semanticscholar   +1 more source

The contribution of hormone sensitive lipase to adipose tissue lipolysis and its regulation by insulin in periparturient dairy cows

Scientific Reports, 2018
Hormone sensitive lipase (HSL) activation is part of the metabolic adaptations to the negative energy balance common to the mammalian periparturient period. This study determined HSL contribution to adipose tissue (AT) lipolysis and how insulin regulates
J. De Koster, R. Nelli, C. Strieder-Barboza, J. de Souza, A. Lock, G. A. Contreras   +5 more
semanticscholar   +1 more source

Effects of epinephrine, corticotropin, and thyrotropin on lipolysis and glucose oxidation in rat adipose tissue

Journal of Lipid Research, 1967
(Log dose)-response curves have been determined for lipolysis and for the conversion of glucose-14C to 14CO2 by adipose tissue from rats in the presence of epinephrine, corticotropin, and thyrotropin.
George A. Bray
doaj  

Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice

Frontiers in Physiology, 2018
Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis. Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice.
Qun Du, Shuihong Zhang, Aiyun Li, I. Mohammad, Bao-lin Liu, Yanwu Li   +5 more
semanticscholar   +1 more source