Results 91 to 100 of about 38,790 (251)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Investigation of the anti-Huanglongbing effects using antimicrobial lipopeptide and phytohormone complex powder prepared from Bacillus amyloliquefaciens MG-2 fermentation

Frontiers in Microbiology
Global citrus production has been severely affected by citrus Huanglongbing (HLB) disease, caused by Candidatus Liberibacter asiaticus (Clas), and the development of effective control methods are crucial. This study employed antimicrobial lipopeptide and
Zhicheng Ding, Yang Liu, Shaoran Zhang, Fangkui Wang, Qi Zong, Yuehua Yang, Anna Du, Yajie Zheng, Jian Zhu, Ling Jiang   +9 more
doaj   +1 more source

In Vitro and Ex Vivo Antibiofilm Activity of a Lipopeptide Biosurfactant Produced by the Entomopathogenic Beauveria bassiana Strain against Microsporum canis

Microorganisms, 2020
Microsporum canis is one of the most important dermatophyte causing tinea corporis and tinea capitis and its biofilm-form has a poor therapeutic response. The biosurfactant production by entomopathogenic fungi (EPF) has not been reported yet.
Marwa M. Abdel-Aziz, Mohsen S. Al-Omar, Hamdoon A. Mohammed, Tamer M. Emam   +3 more
doaj   +1 more source

Molecular model for the self-assembly of the cyclic lipodepsipeptide pseudodesmin A [PDF]

, 2019
Self-assembly of peptides into supramolecular structures represents an active field of research with potential applications ranging from material science to medicine.
Crowet, Jean-Marc, Deleu, Magali, Fehér, Krisztina, Laurin, Yoann, Lins, Laurence, Martins, José, Sinnaeve, Davy   +6 more
core   +4 more sources

MMP2‐Responsive Liposomes Targeting LDLR Enhance the Effectiveness of Anti‐Cancer Drugs in Treating Melanoma

Advanced Therapeutics, Volume 9, Issue 1, January 2026.
A bi‐functional liposomal system is developed to enhance melanoma therapy, combining mApoE‐mediated targeting of LDLR‐expressing tumor cells with MMP2‐responsive drug release. Loaded with Pimasertib, the liposomes improve intracellular delivery, reduce melanoma viability, and inhibit 3D spheroid growth and invasiveness.
Antonio Renda, Antonia I. Antoniou, Marika Quadri, Susanna Comi, Arianna Amenta, Silvia Sesana, Sara Pellegrino, Pierfausto Seneci, Marcus Koch, Vanna Denti, Giuseppe Paglia, Elisabetta Palazzo, Roberta Lotti, Alessandra Marconi, Francesca Re   +14 more
wiley   +1 more source

Biomedical and therapeutic applications of biosurfactants [PDF]

, 2010
During the last years, several applications of biosurfactants with medical purposes have been reported. Biosurfactants are considered relevant molecules for applications in combating many diseases and as therapeutic agents due to their antibacterial ...
A. Bernheimer, A. Fiechter, A. Flasz, A. Singh, A.B. Moldes, A.L. Moyne, B. Angelova, B. Gan, C. Carrillo, C. Delden Van, C. Heinemann, C.G. Hoogmoed Van, C.L. Wang, C.N. Mulligan, D. Kitamoto, D. Kitamoto, D. Vollenbroich, D. Vollenbroich, D.J. Bidel, D.R. Mack, F. Ahimou, F. Besson, F. Ramisse, G. Reid, G. Reid, G. Reid, G. Reid, G. Reid, H. Isoda, H. Isoda, H. Itokawa, H. Sano, H.J. Busscher, H.J. Busscher, H.J. Busscher, I. Grangemard, I.M. Banat, I.M. Banat, I.M. Banat, I.N.A. Bogaert Van, J. Gerard, J. Im, J.D. Desai, J.D. Hamme Van, J.D. Sheppard, J.H. Im, J.R. Mireles, J.R. Wright, K. Das, K. Das, K. Jenny, K. Kim, K. Millsap, K. Mittenbuhler, L. Thimon, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, M. Benincasa, M. Konishi, M. Morikawa, M. Shibahara, M. Velraeds, M. Velraeds, M. Velraeds, M. Velraeds, M. Yakimov, N. G. Dehghan, N. Kosaric, N. Kosaric, N. Naruse, O.M.P. Rivera, P. Gotek, P. Singh, R. Maier, R. Makkar, R. Sen, R.M. Maier, R.T. Otto, S. Boris, S. Cameotra, S. Cameotra, S. Igarashi, S. Ito, S. Joshi, S. Lang, S. Lin, S. Lin, S. Mukherjee, T. I. Pratt, T. Kikuchi, T. Kikuchi, T. Neu, T. Nielsen, T. Sudo, V. Shah, X. Zhao, X. Zhao, Y. Inoh, Y. Inoh, Y. Ishigami, Y. Kameda, Y. Maitani, Y. Tanaka, Y. Uchida, Y. Uchida, Y. Ueno, Y. Ueno, Y. Wakamatsu   +114 more
core   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

The action mechanism of daptomycin [PDF]

, 2016
The final publication is available at Elsevier via http://dx.doi.org/10.1016/j.bmc.2016.05.052 © 2016.Daptomycin is a lipopeptide antibiotic produced by the soil bacterium Streptomyces roseosporus that is clinically used to treat severe infections with ...
Palmer, Michael, Taylor, Scott D.
core   +1 more source

Metabolism‐Regulating Nanomedicines for Cancer Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley   +1 more source

Solubilization and enhanced degradation of benzene phenolic derivatives—Bisphenol A/Triclosan using a biosurfactant producing white rot fungus Hypocrea lixii S5 with plant growth promoting traits

Frontiers in Microbiology
IntroductionEndocrine disrupting chemicals (EDCs) as benzene phenolic derivatives being hydrophobic partition to organic matter in sludge/soil sediments and show slow degradation rate owing to poor bioavailability to microbes.MethodsIn the present study,
Mridula Chaturvedi, Navpreet Kaur, Pattanathu K. S. M. Rahman, Shashi Sharma   +3 more
doaj   +1 more source