Results 51 to 60 of about 38,790 (251)

Unraveling the senses of Phytophthora; leads to novel control strategies? [PDF]

, 2009
Oomycetes cause devastating diseases on plants and animals. They cause major yield losses in many crop plants and their control heavily depends on agrochemicals. This is certainly true for the potato late blight pathogen Phytophthora infestans.
Govers, F., Meijer, H.J.G., Raaijmakers, J.M., Tran, H., Wagemakers, L.   +4 more
core   +2 more sources

Immunostimulation by synthetic lipopeptide based vaccine candidates: structure-activity relationships.

Frontiers in Immunology, 2013
Peptide based vaccines offer several advantages over conventional whole organism or protein approaches by offering improved purity and specificity in inducing immune response. However, peptides alone are generally non-immunogenic.
Mehfuz eZaman, Istvan eToth, Istvan eToth   +2 more
doaj   +1 more source

Recent Advances in Toll Like Receptor-Targeting Glycoconjugate Vaccines

Molecules, 2018
Many malignant cell surface carbohydrates resulting from abnormal glycosylation patterns of certain diseases can serve as antigens for the development of vaccines against these diseases.
Qingjiang Li, Zhongwu Guo
doaj   +1 more source

Biosynthesis, chemical structure, and structure-activity relationship of orfamide lipopeptides produced by Pseudomonas protegens and related species [PDF]

, 2016
Orfamide type cyclic lipopeptides (CLPs) are biosurfactants produced by Pseudomonas and involved in lysis of oomycete zoospores, biocontrol of Rhizoctonia and insecticidal activity against aphids.
Geudens, Niels, Höfte, Monica, Kieu Phuong, Nam, Ma, Zongwang, Martins, José, Ongena, Marc, Sinnaeve, Davy   +6 more
core   +3 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Characterization and Antimicrobial Studies of Iturin-Like and Bogorol-Like Lipopeptides From Brevibacillus spp. Strains GI9 and SKDU10

Frontiers in Microbiology, 2021
Accession numbers for whole-genome sequence of Brevibacillus sp. strain GI9 and SKDU10 are CAGD01000001 to CAGD01000061 and LSSO00000000, respectively. Members of the genus Brevibacillus have been demonstrated to produce a variety of bioactive compounds ...
Shelley Sardul Singh, Deepika Sharma, Piyush Baindara, Stanzin Choksket, Harshvardhan, Santi M. Mandal, Vishakha Grover, Suresh Korpole   +7 more
doaj   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Study on Antifungal Mechanism of Lipopeptide Extract from Bacillus amyloliquefaciens Against Alternaria alternata in Tomato

Guangdong nongye kexue
【Objective】This study elucidated the antifungal rate and mechanism of lipopeptide extracts from Bacillus amyloliquefaciens against Alternaria alternata in tomatoes, aiming to provide scientific basis for green control of black spot disease in tomatoes ...
Yingying FAN, Yingying DAI, Yuanyuan ZHANG, Tingting SHEN, Yan WANG, Peicheng WANG, Fengjuan LIU, Cheng WANG   +7 more
doaj   +1 more source

MICROBIAL SURFACTANTS. II. LIPOPEPTIDES [PDF]

Biotechnologia Acta, 2014
The classification and the chemical structure of the lipopeptides and their producers (bacteria of the genera Bacillus and Pseudomonas) are given. The role of the lipopeptides in cells motility, biofilm formation, metal binding and xenobiotics degradation and their action on the cells of pro- and eukaryotes is summarized. The stages of the nonribosomal
T. P. Pirog, A. D. Konon, A. P. Sofilkanich   +2 more
openaire   +2 more sources

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

Advanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins   +9 more
wiley   +1 more source